MSMEG5669
ms5669
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 5759843 – 5760928
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG5663 MSMEG5664 MSMEG5665 MSMEG5666 MSMEG5667 MSMEG5668 MSMEG5669 MSMEG5670 MSMEG5671 gltA
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms5669_MSMEG5669_dna
GACGGCTGTGCATCGAGGCGAAGACCACGGTGGATCTGGAGCGCAGCCTCGGCATGACCGCGGGCAACATCTTCCACGATGCGCTGCGCTGGCCGTTCGTCGACGACGACGAACCGCTGGACACCCCGGCGCAACGCTGGGGTGTGGCCACCGGCCACGAGCGGATCCTGTTGTGCGGGTCGGGTTCCCGCCGCGGTGGCGCGGTGTCGGGCGTCGGTGGCCACAACGCCGCGATGGCGGTGCTCGAACGCGTCTAGTGTCCTGAGTCATTAATTGCGGCCTAGTTGTTAAACTAGGTCGTGCCGACTCCTCATGCCGCTGAGATTGTGTTGTCCGCTGATGAGCGGGCCGAGTTGGAGGGCTGGGCGCGGCGACGTACGAGTGCTGCCGGCCTGGCCATGCGGGCTCGAATTGTGTTGGCAGCTGCCGATGGTGGGTCCAATACTGAACTGGCCGATCGCCTGGAGTTGTCGATCGGCACGGTGCGGCGCTGGCGCAATCGGTTCGCTGAGCTGCGACTGGACGGCCTCGTTGATGAACCACGTCCGGGTCGGCCGCGGGTTGTCGGTGACGAGCAGATCGAAGCGTTGATCACCGCGACGTTGGAGACCACCCCGCCTGATGCCACCCATTGGTCAACCCGCTCGATGGCTGCCCATCTGGGGTTGAGTCAGTCGATGGTCTCGCGCGTCTGGCGAGCGTTCGGACTGGCTCCCCACAAGCAGGACTCGTGGAAACTGTCGAAAGACCCGCTGTTTGTGGCCAAGGTCCGCGATGTCGTCGGGCTGTACCTGAACCCACCGGAACGGGCCTTGGTGCTGTGCGTGGACGAGAAAACCCAGATCCAGGCACTGAACCGGACCCAACCGGTGTTCCCGATGTTGCCCGGCACCCCGGCGCGGGCCAGCCATGACTACGTTCGCCACGGCACCTCCAGCCTCTACGCCGCTCTCGACCTGACCACCGGCAAGGTGATCGGCGCCCTGCACTCTCGCCACCGAGCCACGGAGTTTCTGGCTTTTCTCAAGAAGATCGACGTCGAGGTCCCCGACGATCTTGATGTGCACTTGGTTCTCGACAACGCCTCCACGCACAAGACCCCTGCGGTAAAACGTTGGCTGACAGGCCATCCCAGATTTGTCCTGCACTTCACCCCGACCAGCTCGTCCTGGCTCAATCTCGTGGAACGCTGGTTCGCCGAGCTGACCACCAAGAAGCTGCGACGCTCCACCCACACCTCAGTTCGGCAACTCAACGCCGACATCCGAGCGTGGATCGACACCTGGAACGACAACCCCAAGCCCTACGTCTGGACCAAGACCGCCGATCAAATCCTGGCCAGCATCGCCAACTACTGCGCCCGAATTAATGACTCAGGACACTAG

Protein Sequence 

>Ms5669_MSMEG5669_protein
VPTPHAAEIVLSADERAELEGWARRRTSAAGLAMRARIVLAAADGGSNTELADRLELSIGTVRRWRNRFAELRLDGLVDEPRPGRPRVVGDEQIEALITATLETTPPDATHWSTRSMAAHLGLSQSMVSRVWRAFGLAPHKQDSWKLSKDPLFVAKVRDVVGLYLNPPERALVLCVDEKTQIQALNRTQPVFPMLPGTPARASHDYVRHGTSSLYAALDLTTGKVIGALHSRHRATEFLAFLKKIDVEVPDDLDVHLVLDNASTHKTPAVKRWLTGHPRFVLHFTPTSSSWLNLVERWFAELTTKKLRRSTHTSVRQLNADIRAWIDTWNDNPKPYVWTKTADQILASIANYCARINDSGH

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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