MSMEG5891
ms5891
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 5951872 – 5952933
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG5887 MSMEG5888 MSMEG5889 MSMEG5890 MSMEG5891 MSMEG5892 MSMEG5893 MSMEG5894 MSMEG5895 MSMEG5896
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms5891_MSMEG5891_dna
GTTTCCGGCAGCAGTTCGAGAGCGACGCCCAGCAGAAGGTGATCCCGGAGGCCCGCAAGCGCGAGCTCGTGGTGCAGATCAACATCGTCGGCGTCGGTGTCGAGGCCGCGCAGCGCGACACCGGATCGGTGCTGGTGTACATGAACCGCACGGTCACCGACAAGTCGCGCCAGCCGCTCTACGACGGCAGCCGGCTGCGCGTCGAGTACCGCAAGGTCGACGGCAAGTGGCTGATCGACGCCATCAAGCCGATCTAGTGTCGCGCGTCATTAATTAGTTTACAGTGTGGGATGATGGTGTATGCCGTCATCCACATTGGTGATCAGTTCTGAAGATCGTGTGACGTTGGAGTCGTGGACGCGGTCCTCGACGGTGCCTGCCGGCCGTGTTGAGCGGGCGCGGATCGTGCTGGCGGTGGCCGACGGTGCGGGGACCTCGGGTGCGGCGCGGCAGGTGGGGGTGTCGCGGCCGACGGTGATCAAGTGGCGGGATCGGTTCGCCGCGTTCGGCATTGAGGGGCTTGATGACGAACCACGCAGCGGCCGACCCAAGACGGTCGATGACGCCGAGATCCTGGCGACCACGCTCGAGCCGCCACCGGAATCGTTGGCCGTGACCCACTGGTCGAGTCGACTGCTCGGAAAGCACCTCGGGATCGGGGATGCCACGGTGGCCCGGGCGTGGCGACGCTACGGGGTCAAACCGTGGCGGCGCGAGACGTTCAAGTTCTCCACCGACCCTGAACTGGAGGCCAAGGTCCGTGACGTGATCGGCCTGTATCTGAACCCACCAGAAAAGGCGGTCGTGTTGTGCGTGGACGAAAAGAGCCAGATTCAGGCACTCAACCGCACCCAGCCGATTTTGCCGTTGCGTCCGGGACTGCCGGAGAAGGCGACCCACGACTATCAGCGCAACGGCACCGCCACGTTGTTCGCCGCCTTGGAAATCGCAACCGGCAAAGTGACCGACCGCTGCTACGAGCGGCACGGCAAAGCCGAGTTCCTCGATTTCCTCAAGACGGTCGCCCGGGCCTACCCGCGCCGCAAACTGCATGTGGTGTGCGACAACTACCACACCCACAAACACGCTGACATCAATGCGTGGTTGGTCAAGAATCCCCGCGTGACACTGCATTTCACCCCGACCTCAGGCTCCTGGTTGAACCTGGTCGAGGTGTTCTTCTCGATCATCACCCGCCAAGCAATCCGCCGGGGCTCGTTCAACAGCGTTAAAGAACTCATCGCTGCCATCAGCGCCTTCATCGAGGGCTGGAACCAACGCGCCCACCCATTCGTGTGGACCAAGACCGCCGACGAAATCCTGCCCCACACTCGTAAACAAACTTCAGACGCGCGACACTAG

Protein Sequence 

>Ms5891_MSMEG5891_protein
MPSSTLVISSEDRVTLESWTRSSTVPAGRVERARIVLAVADGAGTSGAARQVGVSRPTVIKWRDRFAAFGIEGLDDEPRSGRPKTVDDAEILATTLEPPPESLAVTHWSSRLLGKHLGIGDATVARAWRRYGVKPWRRETFKFSTDPELEAKVRDVIGLYLNPPEKAVVLCVDEKSQIQALNRTQPILPLRPGLPEKATHDYQRNGTATLFAALEIATGKVTDRCYERHGKAEFLDFLKTVARAYPRRKLHVVCDNYHTHKHADINAWLVKNPRVTLHFTPTSGSWLNLVEVFFSIITRQAIRRGSFNSVKELIAAISAFIEGWNQRAHPFVWTKTADEILPHTRKQTSDARH

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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