MSMEG6146
ms6146
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 6214302 – 6215708
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Li, 2017 (5) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 29326668 MSMEG6143 MSMEG6144 MSMEG6145 MSMEG6146 MSMEG6147 MSMEG6148 MSMEG6149
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms6146_MSMEG6146_dna
GCAGGTCCTGGACCAGATTCGTCAACAGACGAGCGATATGTCGATACAGGACCTCTCCGAGGTCGACAGGAAACTCGGCGAGAACAAGGGCCTGCTTACCAACGCGTTCCAAGTCCTGAGCGACCCCGATGTGAAGATACCTCTGGAAAAGAATGTTCCCGGCCCCTTCGCAGACCTAGCCCAGATTTTTCGCGGATTATCTCTGGTGAGGGCGTGTAGATAAGCGAAAGTGCCTGTCCTGCAAGGGATAATTGGACTTCTCTAGGGTTCAACCATCCTGACGGGAAGGCACTTCGCAGGTGAAGAGTATCGCGGCCGCATCGCGGGTGAAAGTGTCAGCCGACGGCCACGGGGTCGTGTCGCACGCCGGGATGGGCCTACTGCGGGAACTGGCCGACCGGACCGGCCTATCAGCGCAGGTCACCGGCGCTTTGGCCGACACCTACCGCGGGCCGTGGACCTACGCACCCGGCGAGGTGTTCGCCGATCTGGCCGCGGCGGTCGCCGACGGCGCGGACTGCATTGACGGGGTCGGCCAACTGTGCGGCGACCGTGAGCACGCGTTCGGCGCGAAAGCCTCCACGACCACGATGTGGCGGCTGGTCGATGAGCGCATCGACGCCGCACACCTGCCTGCGGTGCGCGCGGCCCGCGCCAGCGCGCGGGCGGCGGCCTGGGCCGCCGGTGCGGCCCCCGAACCGGGTGGCTGGCTGCACATCGACATCGACGCCACCGTGGTGATCGATCACTCCGACAACAAACACGGCGCGACGCCGACCTGGAAGAAAACGTTCGGACACCATCCGCTGCTGGCGTTCCTGGACCGCCCCGAGATCGCCGGCGGGGAAGCCCTGGCCGGGCTGCTGCGCAGCGGCAACGCGGGCTCCAACACCGCCAGCGACCACATCATCGTCCTGGCCCAGGCGCTGGCAGCGCTGCCCGCGCCGTGGCGGCCCGACTCGAGTCGTGGCGGTGATCCCGACCGGCCCCAGGTGCTGGTGCGTTGCGACACCGCCGGAGCCACCCACCGATTCGCCGACGCCTGCCGCGAGCAGGGAGTCGGATTCTCCTTCGGCTACCCCGTCGACGCCCGCGTCCAGGACGCCGCCGACACCCTCAACCTTGCCGAGGGCTGGTACCCGGCCATCGACACCGACGGCGGCATCCGTGACGGCGCCTGGGTCGCCGAGGCCACCACCTTGGTCAACCTCAACAGCTGGCCGCCGGGCACCCGGCTGATCCTGCGCAAGGAGAGACCGCATCCCGGCGCCCAGCTGCGGTTCACCGACACCGACGGAATGCGCGTCACCGCGTTCATCACCGACACACCCACCGGTGTCGTGGCCGGCCAAGTCGCCGGCCTGGAGTTGCGGCACCGCCAGCACGCCCGCGTCGAGGACCGCATCCGCGAACTCAAGAACACCGGCCTACGCAACCTGCCGTGTCACGGCTTCTGGGCCAACGCCGCCTGGCTCGAGATCGTCCTGGCCGCCACCGACCTGGTCACCTGGGCACGGCTCATCGGATTCACCAGTGATCCGACGCTGGCCCGCGCCGAGATCGCCACGTTCCGCTACCGCGTGCTGCACGTCGCAGCCCGCATCACCCGCGGCGCCCGCCAACTCCGGCTGCGCATCGACGCCACCTGGCGCTGGGCATCGGCGATCGCCACCGCCTGGCAACACCTGCGCACCGCCTTCGGATAA

Protein Sequence 

>Ms6146_MSMEG6146_protein
VKSIAAASRVKVSADGHGVVSHAGMGLLRELADRTGLSAQVTGALADTYRGPWTYAPGEVFADLAAAVADGADCIDGVGQLCGDREHAFGAKASTTTMWRLVDERIDAAHLPAVRAARASARAAAWAAGAAPEPGGWLHIDIDATVVIDHSDNKHGATPTWKKTFGHHPLLAFLDRPEIAGGEALAGLLRSGNAGSNTASDHIIVLAQALAALPAPWRPDSSRGGDPDRPQVLVRCDTAGATHRFADACREQGVGFSFGYPVDARVQDAADTLNLAEGWYPAIDTDGGIRDGAWVAEATTLVNLNSWPPGTRLILRKERPHPGAQLRFTDTDGMRVTAFITDTPTGVVAGQVAGLELRHRQHARVEDRIRELKNTGLRNLPCHGFWANAAWLEIVLAATDLVTWARLIGFTSDPTLARAEIATFRYRVLHVAARITRGARQLRLRIDATWRWASAIATAWQHLRTAFG

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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