eccD1
mL0047c
ESX CONSERVED COMPONENT ECCD1. PROBABLE TRANSMEMBRANE PROTEIN.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 58020 – 59558
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0047c_eccD1_dna
TTGAGCGCGCCTGCTGTAACTGCTGGCCCGGCCACTGCCGGGATCACTCCTGCGCGACCTTCCGCGACCCGGGTGACGATTCTTACTGGCAAACGTATGACCGACCTGGTGCTGCCCTCGACGGTGTCGATCGAGGCCTACATTGATGAAACCGTAGCGGTGCTATCCGACCTGCTCGAAGACGCACCGGCGGATGTCCTGGCGGGCTTCGACTTTTCCGCCCAGGGTGTGTGGACATTTGCCCGGCCCGGATCGCCACCCATGAAACTCGACCAGTCGCTCGATGATGCCGGGGTTGTCGACGGGTCGCTGTTGACCCTGGTGTCAACGAGTCGCACAGAACGGTATCGGCCGCTGGTCGAAGACGTCATCGACGCGATCGCAGTGCTCAACGAATCGCCAGAGTTCAATCGCAAGGCGGTGGACCGTTTTATCGGGGTGGCAATCCCCGTCTTGAGCCTGCCGATCACTGCCGTCGCGGTGTGGGCCTGGTGGGTAACCGGGCGCAGCCCATTCTGGTCGCTGGCGATCGGCATCCTGAGCATCGTTGCGCTGACCGGCAGCATCGTCGCCGAAAAATTCTACAAAAATCTGGATCTTTCTGAGAGCCTGCTGCTCACTTCGTACCCGCTGATCGCCAGTGCCGCGGCGTTGGTCACCCCGCTACCAAATGGGGTCGACTCGTTGGGGCCGCCGCAGGTTGCTGCTGCTGCGGCGGCTGTCCTGTTTTTAACCCTGCTGACCCGGGGAGGCGCCCGACGGCATTCTGGCTACGCCTCGTTCACCGCGATCACCACGATCGCGATCGTGGTGATCGCCATTGCGTACGGCTTTGGCTACCAGCACTGGGTGCCGACCGGGGCAGTTGCCTTCGGGCTGTTCATCGTGACGAACGCAGCCAAGCTGACCGTTGCCGTCGCCCGGATCGCTCTACCACCGATACCCGTTCCCGGCGAGACCGTAGACAACGAAGAATTGCTTGATCCCGTTGTCACTCCGCACGAGGCTACTCATGAAGAGACGCCAACCTGGCAGGCCATCATCGCTTCCGTGCCTGACTCCGCGGTGCGGCTTACCGAACGCAGCTCCTTGGCCAAACGGTTGCTGATCGGTTACGTCATATCCGGCACCCTAATTTTGTGTTCCGGTGCTATCGCGGTGATCGTGCGCGGACACTTCTTCGCACATAGCTTAGTGGTGGCGTTTCTGCTAACGGTGGTGTGCACGTTTCGGTCGCGACTCTACGCCGAGCGTTGGTGCGCATGGGCGCTACTGGCAGCCGCCGTTGTGATTCCGACCGGGTTGACCGTCAAGCTATGTATCTGGTACACGCAGATTGCCTGGCTATTGCTGACCAGCTACCTGGTGGCAGCCATTATTGCACTGATGGTATTTGGAGCAACGGTCAGGGTTCGTCGTGTTTCACCGGTGACGAAGCGGATTATGGAATTGATCGACGGCGCGGTGGTCGCATCCATCATTCCGCTGCTGTTGTGGATCGCCGGCGTTTACGATATGGTCCGCAACCTAAGCTTTTAG

Protein Sequence 

>ML0047c_EccD1_protein
LSAPAVTAGPATAGITPARPSATRVTILTGKRMTDLVLPSTVSIEAYIDETVAVLSDLLEDAPADVLAGFDFSAQGVWTFARPGSPPMKLDQSLDDAGVVDGSLLTLVSTSRTERYRPLVEDVIDAIAVLNESPEFNRKAVDRFIGVAIPVLSLPITAVAVWAWWVTGRSPFWSLAIGILSIVALTGSIVAEKFYKNLDLSESLLLTSYPLIASAAALVTPLPNGVDSLGPPQVAAAAAAVLFLTLLTRGGARRHSGYASFTAITTIAIVVIAIAYGFGYQHWVPTGAVAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVVTPHEATHEETPTWQAIIASVPDSAVRLTERSSLAKRLLIGYVISGTLILCSGAIAVIVRGHFFAHSLVVAFLLTVVCTFRSRLYAERWCAWALLAAAVVIPTGLTVKLCIWYTQIAWLLLTSYLVAAIIALMVFGATVRVRRVSPVTKRIMELIDGAVVASIIPLLLWIAGVYDMVRNLSF

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccD1 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

11 show intermediate predicted evidence for PPIs

52 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccD1

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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