esxB
mL0050c
Possible 10 KDA culture filtrate antigen homolog EsxB (lhp) (cfp10)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 61720 – 62022
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0050c_esxB_dna
ATGGCAGAAATGATCACCGAGGCCGCGATCCTCACCCAGCAGGCAGCACAGTTCGATCAAATTGCGTCCGGCCTCAGCCAAGAACGGAACTTTGTTGACAGCATCGGACAGAGCTTTCAGAACACCTGGGAGGGCCAGGCCGCCTCGGCAGCCCTTGGTGCGTTGGGGCGCTTCGACGAAGCCATGCAAGACCAGATCAGACAGCTGGAAAGCATCGTCGATAAGCTGAACCGGTCCGGCGGCAACTACACCAAGACCGACGATGAAGCAAACCAATTGTTGTCCTCGAAGATGAACTTCTGA

Protein Sequence 

>ML0050c_EsxB_protein
MAEMITEAAILTQQAAQFDQIASGLSQERNFVDSIGQSFQNTWEGQAASAALGALGRFDEAMQDQIRQLESIVDKLNRSGGNYTKTDDEANQLLSSKMNF

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EsxB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

21 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EsxB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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