eccB1
mL0054c
ESX CONSERVED COMPONENT ECCB1. POSSIBLE MEMBRANE PROTEIN.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 67417 – 68862
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0054c_eccB1_dna
ATGGGGCTTCGCCTGACCACCAAGGTTCAGGTCAGCGGCTGGCGCTTCCTGCTTCGCAGGGTTGAGCATGCCATCGTGCGGCGCGACACTCGGATGTTCGACGACCCGCTGCAGTTCTACAGTCGCTCGATCGCCCTTGGCATCGTTGTTGCGGTTGCGCTCCTGATAGGCGCCGTCCTGCTGGCGTACTTCAAACCACAGGGCAAGCTAGGTGCCAGCACCCTTCTGACCGATCGGGCAACCAATCAGCTCTACGTGCTCTTGTCCGGGCATCTGTATCCAGTGTACAACTTGACCTCGGCGCGACTGGCGCTGGGCAAACCGGCTAACCCAGCTGCCGTGAAGTCCAGCGAATTGACCAAGCTGCCTATAGGTCAGACCATCGGAATCCCTGGTGCACCCTACGCCACGCCTGTTTCAGGGGATTCCTCGTCAACCTGGACCTTGTGCGACACCGTCGCCAAGATCGAGAGCGAATCGCCGGCGGTGCAGACTTCGGTTATAGCTCGATCACTACAGATCGACCCTGCGATAAATCCATTGCAACCGAACGAAGCGCTACTGGCGTCATACCGGGACAAAACGTGGCTAGTTAACTCAAAAGGGCGGCACTCCATCGATCTGGCCGACCGGGCCCTAACCTCGGCCATAGGAATATCGGTAAACGTTAAGCCAACCCCACTCTCTGAGGGCCTGTTCAACGCACTACCCGACGTCGGCAGGTGGGAGCTGCCGACGATTCCTGACACTGGAGCACCTAATTCGCTGGGGTTATCCCCAGACCTCGTAATTGGGTCGGTGTTCCAAATCCAAATGGAAAAGAGCCCACAGTACTACGTGGTACTCTCCGACGGCATCGCCCAGGTGAATGCCACCACCGCTGATGCGTTGCGCGCTACCCAGTCGCATGGACTGGTAGCGCCTCCATCACTGGTACCAAACGTGGTCGTCCAGATTCCCGAACGGGTCTACGACTCGCCACTGCCCGATGAACCACTCAAGATGGTGGCCCGGGACGACTACCCAACGCTGTGTTGGGCATGGGAACGCAAAGCCAGTGATCAGGCGCCGAAGAGAACCATGTTGATTGGTCAGCATCTGCCACTACAGCCGTCAGCCATGAGCACAGGTATAAAACAGATCCGTGGGACAGCAACCGTCTATATTGATGGTGGCAGATACGTGGCGCTACAGTCTCCAGACCCCCGGTACAGTGAATCCCTGTACTACGTTGATCCGGAGGGAGTACGTTACGGCCTGGCGAACTCGGAGGCGGTGAAGGCGCTGGGCCTCGCTTCACCGCAGACAGCGCCCTGGGTGATCGTTCGTCTTCTGGTGGAGGGGCCTGTGCTCTCCAGAGACGCAGCTCTGTTAGAGCACGATACGCTGATCGCGGACCCAAGCCCACGGAAAGTACCAGCCGGCTACTCTGGAGTGAGGCCATGA

Protein Sequence 

>ML0054c_EccB1_protein
MGLRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVALLIGAVLLAYFKPQGKLGASTLLTDRATNQLYVLLSGHLYPVYNLTSARLALGKPANPAAVKSSELTKLPIGQTIGIPGAPYATPVSGDSSSTWTLCDTVAKIESESPAVQTSVIARSLQIDPAINPLQPNEALLASYRDKTWLVNSKGRHSIDLADRALTSAIGISVNVKPTPLSEGLFNALPDVGRWELPTIPDTGAPNSLGLSPDLVIGSVFQIQMEKSPQYYVVLSDGIAQVNATTADALRATQSHGLVAPPSLVPNVVVQIPERVYDSPLPDEPLKMVARDDYPTLCWAWERKASDQAPKRTMLIGQHLPLQPSAMSTGIKQIRGTATVYIDGGRYVALQSPDPRYSESLYYVDPEGVRYGLANSEAVKALGLASPQTAPWVIVRLLVEGPVLSRDAALLEHDTLIADPSPRKVPAGYSGVRP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccB1 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

16 show intermediate predicted evidence for PPIs

66 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccB1

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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