eccA1
mL0055c
ESX CONSERVED COMPONENT ECCA1
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 68866 – 70587
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0055c_eccA1_dna
ATGATTGATCGCCTGGGCAGCCTATTCGAAAGCGCCGCCAGCATGTTGCCCATGTCGGAGGCGCGATCGTTTGAGCTGTTCACCGAAATCACGAATTACGACGAGACTGCCTGCGACGCATGGATCGGCCGGATCCGCTGCGGCGACACCGACCGAGTGACACTGTTTCGTGCCTGGTATTCGCGAAGGAACTTCGGGCAGTTGTCGGGATCTGTCCAGATCCCGATGACCACCCTCAACGCCAGAGTTCCCATCGGAGGGCTATACGGCGACATCACTTACCCGGTCACTTCTCCGCTAGCTATCACTATGGGTTTCGCCGCGTGCGAAGCGGCTCAAGGTAACTTCGCCGACGCTATGGAAGCGATTGATGCCACTTCGATCACCGGCTCCGAACATCTAGTGGCCTGGCTCAAGGCGGTGGTCTACGGCGCAGCCGAACGATGGACCGACGTGATCGACGAAGTCAAGGGTGCCGGGAAATGGCCGGACAAGTTCCTAGCTGGCGCCGCTGGCGTCGCACATGGAGTAGCAGCTGCCAACCTCGGTTTGTTCACCGAGGCCGAACGTCGACTTACCGAGGCGAATGACTCCCCGGCCGGCGAAGCGTGTGCACGCTCCATCGCTTGGTATCTAGCAATGGCACGGCGCAGCCAGGGCAATGAAGACGCTGCGGTGGCGCTGCTGGAATGGTTGCAGACCACCCACCCGGAAAGTAAAGTGTCTGCGGCGCTAAAGGATCCGTCCTATCGCCTGACGACAACGACTGCCGAACAGATCGCCGCCCGCGCGGACCCGTGGGATCCGAGCAGTGTGGTTACCGACAACTCCGATCGAGACAGACTGCTCACCCAGGCGCAGGCCGAGCTGGACAGGCAGATTGGGCTCACCAGGGTTAAAACCCAGATAGAGAGGTACCGGGCCGCAACGATGATGGCGAAGGTTCGCGCTGCCAAAGGCATGAAAGTGGCGCAGCCAAGCAAACACATGATTTTCACTGGGCCACCCGGTACCGGCAAGACTACTATCGCGCGGGTGGTGGCCAATATTCTGGCCGGATTGGGTGTCATCTCGGAACCAAAGCTGGTCGAAACGTCACGCAAAGATTTCGTCGCCGAATACGAAGGACAGTCAGCAGTCAAAGCCGCCAAGACAATCGATCTTGCCCTCGGCGGCGTGTTATTCATCGACGAAGCCTACGCACTGGTGCAGGAACGGGACGGGCGCACCGATCCGTTCGGACAAGAGGCGCTGGACACCCTGCTGGCGCGGATGGAAAACGACCGCGATCGACTGGTGGTGATCATCGCCGGCTACAGCTCCGATATCGATCGGCTTCTGGAAACCAACGAAGGTCTGCGATCGCGCTTCGCGACTCGAATCGAATTCGATACCTATTCCCCTGATGAGCTTCTCGAAATCGCGAAAGTCATTGCAACTGATGCCGATTCATCGTTGAGTGCAGAAGCGAGCAAGAATCTGCTGGAAGCGGCTAAGCAGTTAGCCCAGCGGACTTTGCGCGGCAGACCCGCCCTCGACGTTGCCGGCAACGGTCGCTACGCGCGACAATTGGTGGAAGCCGCTGAACAGTGTCGTGACATGCGGCTGGCTCGGGGTGTCGACATCGAGCAACTGGATGTGGACCGACTGCAGGAGATCAACGGCTCAGACATGGCCGAGGCGATCGCCACGGTGCACGCACACCTCAACATAAGAGAGTGA

Protein Sequence 

>ML0055c_EccA1_protein
MIDRLGSLFESAASMLPMSEARSFELFTEITNYDETACDAWIGRIRCGDTDRVTLFRAWYSRRNFGQLSGSVQIPMTTLNARVPIGGLYGDITYPVTSPLAITMGFAACEAAQGNFADAMEAIDATSITGSEHLVAWLKAVVYGAAERWTDVIDEVKGAGKWPDKFLAGAAGVAHGVAAANLGLFTEAERRLTEANDSPAGEACARSIAWYLAMARRSQGNEDAAVALLEWLQTTHPESKVSAALKDPSYRLTTTTAEQIAARADPWDPSSVVTDNSDRDRLLTQAQAELDRQIGLTRVKTQIERYRAATMMAKVRAAKGMKVAQPSKHMIFTGPPGTGKTTIARVVANILAGLGVISEPKLVETSRKDFVAEYEGQSAVKAAKTIDLALGGVLFIDEAYALVQERDGRTDPFGQEALDTLLARMENDRDRLVVIIAGYSSDIDRLLETNEGLRSRFATRIEFDTYSPDELLEIAKVIATDADSSLSAEASKNLLEAAKQLAQRTLRGRPALDVAGNGRYARQLVEAAEQCRDMRLARGVDIEQLDVDRLQEINGSDMAEAIATVHAHLNIRE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccA1 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

12 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccA1

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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