espH
mL0056c
ESX-1 SECRETION-ASSOCIATED PROTEIN ESPH
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 70584 – 71093
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0056c_espH_dna
GTGAACCTGCTCGGGAATGACGACGATAATCACTTGGCAAGCCTAGATTTCTACAGCGCCAACCGCTACTACGAGGAGTCGTTGTTTTTCGACGAGCTCGATGGTTATGCGCCGACAACGCCAGTGGGCATCGAAGCCAACGATCTAGACGTCTTCCAATCTCTGACTGAACCGGAGGAGGAGCTTGAGGTCGAGCTACTCGCGGTGACGAACCCCGCCAAGTCGGTGTCGGCACTCATGAACGGCAGAGTCCACCAGGTTGAGCTGACCGACCAAGTGACTCGGATTGGCGAAAAGAAGCCCGCAACAGAGGCCTTTGTCCTTGCTAGCTTGGCTCGGCAGAAGGCGCGAACCTCCCAGGGCACTTGCATACTCGACAGCCTCCAAGGCGGCGGAGAAAACACAACCGCCAGATGTGAACTAGTAGGGCTGACCCTAAATTTGCCCACGTCGGAACAGGCTGCTGCAGAAGCAGAAATGTTCTCCAACAATATACTTCGGCAAAAATGA

Protein Sequence 

>ML0056c_EspH_protein
VNLLGNDDDNHLASLDFYSANRYYEESLFFDELDGYAPTTPVGIEANDLDVFQSLTEPEEELEVELLAVTNPAKSVSALMNGRVHQVELTDQVTRIGEKKPATEAFVLASLARQKARTSQGTCILDSLQGGGENTTARCELVGLTLNLPTSEQAAAEAEMFSNNILRQK

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EspH with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

19 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EspH

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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