ethR
mL0064c
Probable transcriptional regulatory repressor protein (TetR-family) EthR
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 85968 – 86612
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0064c_ethR_dna
GTGATAAATTCCACTGCCGGACAAACTTCGCAAAGCCGGAGTCGACGCAGCACACGCCCGTCCGGCGACGACCGTGAACTGGCAATCCTGGCCACCGCTGAGCAACTTCTTGAGGACCGACCGCTTACCGAGATCTCGGTAGATTACTTGGCCAAAAGTGCCGGGATTTCGCGGCCAACTTTCTACTTCTATTTCGCTTCCAAGGAAGCTGTGCTATTGACACTGCTGGACCGCGTGTTCAACAAGGCGAACGCTGCCCTCGAAACCCTCATTAAGAATCGAGATAACAAACGCGGCAATAAGTGGCGCACCGGGATCAACGTATTCTTCGAAACCTTTGGATCCCATAAAGCAGTGACCTGTGCGGGGCAAGTCACCAGAGACAATACCGAGGTTCGGAAATTGTGGTCGACCTTCATGCAGAAGTGGATCTCCTACACCGCCGCTGTGATCGATGCCGAACGCAAACGCGGTGTGGCACCAGACACCCTGCCCGCCACAGAATTGGCCACCGCGCTCAACCTGATGAACGAGCGGGCGCTGTTTGCCTCATTCACCGCCGAACAGCCTCACGTCCCGGAGTCCCGGGTGCTCGACACCCTGGTGCACATCTGGGTGAGCAGTATATACAACGAAATTCGCTAA

Protein Sequence 

>ML0064c_EthR_protein
VINSTAGQTSQSRSRRSTRPSGDDRELAILATAEQLLEDRPLTEISVDYLAKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALETLIKNRDNKRGNKWRTGINVFFETFGSHKAVTCAGQVTRDNTEVRKLWSTFMQKWISYTAAVIDAERKRGVAPDTLPATELATALNLMNERALFASFTAEQPHVPESRVLDTLVHIWVSSIYNEIR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EthR with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

13 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EthR

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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