embA
mL0105c
Probable integral membrane indolylacetylinositol arabinosyltransferase EmbA (arabinosylindolylacetylinositol synthase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 139821 – 143156
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0105c_embA_dna
GTGCCCCACGACGGTCATGAACCACCGCAGCGGATCATACGGTTGATCGCCGTCGGTGCAGGAATTACGGGGCTGCTATTATGCGCCGTGGTTCCGTTGCTGCCGGTCAAACAAACCACAGCGACGATCCGGTGGCCGCAAAGCGCCACCAGGGATGGCTGGGTAACCCAAATAACTGCGCCACTGGTGTCCGGAACGCCACGCGCGCTAGATATCTCCATTCCTTGCTCGGCCATGGCTACCTTACCCGACAGCGTAGGACTGGTGGTCTCCACGCTGCCCTCCGGTGGTGTGGATACCGGCAAAAGCGGGCTCTTCGTGCGCGCCAACAAAAACGCGGTCGTCGTTGCATTCCGGGATTCGGTAGCCGCGGTAGCACCACGCCCAGCGGTGGCCGCTGGCAACTGTAGCGTCTTGCACATCTGGGCCAACACCCGCGGCGCAGGCGCGAATTTTGTCGGCATACCAGGGGCCGCAGGAATTTTAACAGCTGAGAAAAAACCACAGGTAGGTGGGATCTTCACCGACCTGAAAGTGCCCGTACAACCCGGGCTGTCGGCCCACATAGACATCGACACCCGCTTCATCACGGCGCCTACCGCGATCAAGAAGATCGCGGTAGGCGTGGGTGCGGCGGCGGTCCTGATCGCCATACTCGCGCTGTCGGCCCTGGACCGACGCAACCGGAACGGCCACCGCCTGATCAACTGGCGGGTGTCGATGGCTTGGCTGGCCCAGTGGCGCGTCATCCTGGCGACTCCCCCACGAGCAGGAGGTGCCTCCAGGATCGCGGACGGGGGAGTACTCGCGACGCTACTGTTGTGGCACATCATTGGCGCCACCTCGTCGGACGACGGCTATAATCTGACCGTAGCGCGAGTCTCGTCGGAGGCCGGCTATTTAGCCAACTATTACCGATACTTCGGTGCGACGGAGGCGCCGTTCGATTGGTATTTCACCGTGCTGGCCAAATTAGCGTCGGTAAGTACCGCCGGTGTGTGGATGCGGATACCGGCCACGCTAGCCGGTATCGCATGCTGGCTCATAATCAACCATTGGGTGCTGCGGCGGCTGGGCCCCGGAACGGGTGGTCTGTCGACCAACCGGGTGGCAGTGCTCACCGCGGGTGCGATGTTCCTGGCCGCGTGGCTGCCGTTCAACAACGGGCTGCGTCCTGAGCCGCTGATTGCGCTCGGTGTGCTGTTCACATGGGTGCTGGTGGAACGCGCCATCGCACTGCGGCGACTGGCTTCGGCCGCAACTGCGGCGGTGGTCGCTATCCTGACCGCTACCCTGGCACCACAAGGGTTGATCGCTATCGCGGCACTGCTAACCGGGGCGCGGGCCATCACCCAGACGATACGCCGACGCCGGACGACTGACGGATTGCTGGCACCACTGCTGGTGCTCGCGGCGTCTCTTTCGCTGATCACCCTGGTGGTGTTCCATAGTCAAACGCTGGCCACAGTCGGTGAGTCGGCGCGCATCAAGTACAAAGTCGGTCCGACGATCGCCTGTTACCAAGACTTCCTGCGCTACTACTTCCTCACGGTGGAGTCCAACGCCGACGGCTCAATGACCCGGCGGTTCCCGGTGCTGGTGCTGTTGTTGTGCATGTTCGGGGTGCTGGTGGTGTTACTGCGCCGAAGCCGGGTACCGGGGTTGGCCAGCGGCCCGACCTGGCGGCTTATCGGCACCACCGCGACCAGCCTGCTGCTGTTAACGTTCACGCCCACCAAGTGGGCCATCCAGTTCGGTGCGTTAGCTGGATTGACCGGCACGTTCGGTGCTATTGCCGCGTTCGCCTTCGCCCGGATCAGCCTACACACCCGCCGCAATCTGACGGTGTACATTACCGCGCTGCTGTTCGTACTGGCGTGGGCCACCGCCGGCATCAATGGCTGGTTTGGCGTTAGCAATTACGGGGTTCCTTGGTTCGACATCCAGCCCGTCATCGCCGGCCACCCGGTGACGTCGATATTCCTGACATTGTCAATCCTGACCGGGTTACTGGCCGGAGGGCAGCACTTCCGGCTCGACTACGCGAAACACACCGAAGTCAAAGACACCCGCCGCAACCGCTTTCTGGCGACGACCCCGCTGGTGGTGGTCGCGACAACCATGGTCCTATGCGAAGTCGGCTCGCTGGCCAAGGGAGCCGTGGCCCGCTACCCACTCTACACCACTGCCAAGGCCAACCTGGCCGCACTCCGGTCCGGACTCGCACCCAGCGTCTGCGCGATGGCCGATGATGTACTGACCGAGCCCGACCCCAATGCCGGGATGCTGCAGCCAGTTCCGGGACAAATCTTCGGTCCTACCGGGCCGCTGGGCGGGATGAATCCCATCGGCTTCAAACCCGAAGGCGTGAACGACGATTTGAAATCCGATCCGGTGGTGAGCAAACCCGGACTGGTTAACTCCGACGCTTCCCCCAACAAACCCAACGTCACTTTCAGTGACTCTGCGGGCACCGCCGGCGGCAAAGGCCCGGTGGGGGTTAACGGGTCGCATGTGGCGCTGCCGTTCGGCCTGGATCCGGACCGCACACCGGTGATGGGCAGCTACGGCGAAAACACACTCGCCGCCTCGGCCACCTCAGCCTGGTATCAGCTGCCGCTCCATTGGAAAGAAAGCATCGCGGACCGGCCGCTGGTGGTAGTTTCCGCAGCCGGTGCCATCTGGTCCTATAAAGAGGACGGCAACTTCATCTACGGACAATCGCTCAAACTGCAGTGGGGTGTCACCCGTCCCGACGGCATCATCCAGCCACTCGCGCAGGTGATGCCGATCGATATTGGGCCGCAGCCGGCATGGCGCAATCTGCGGTTCCCGCTGACCTGGGCGCCACCGGAAGCCAATGTGGCACGCGTCGTGGCTTACGATCCGAACCTAAGCCCGGATCAATGGCTGGCATTCACTCCGCCGCGGGTGCCGGTCTTACAAACTCTGCAGCAGTTACTTGGGTCGCAGACCCCGGTGCTGATGGACATCGCTACGGCGGCGAACTTCCCCTGCCAGCGGCCATTCTCCGAACACCTTGGCATCGCCGAACTCCCGCAGTACCGCATACTACCCGACCACAAGCAGACAGCTGCATCGTCGAACCTGTGGCAATCCAGCGAGGCCGGCGGCCCGTTCTTGTTCCTGCAGGCGTTACTGCGAACCTCGACGATTTCAACGTACCTGCGGGACGACTGGTACCGGGACTGGGGATCGGTGGAACAGTATTACCGGCTAGTACCCGCCGACCAGGCACCAGAAGCCGTTGTGAAGCAGGGCATGATCACAGTGCCTGGCTGGATCCGTCGAGGACCGATTAGGGCGCTGCCATGA

Protein Sequence 

>ML0105c_EmbA_protein
VPHDGHEPPQRIIRLIAVGAGITGLLLCAVVPLLPVKQTTATIRWPQSATRDGWVTQITAPLVSGTPRALDISIPCSAMATLPDSVGLVVSTLPSGGVDTGKSGLFVRANKNAVVVAFRDSVAAVAPRPAVAAGNCSVLHIWANTRGAGANFVGIPGAAGILTAEKKPQVGGIFTDLKVPVQPGLSAHIDIDTRFITAPTAIKKIAVGVGAAAVLIAILALSALDRRNRNGHRLINWRVSMAWLAQWRVILATPPRAGGASRIADGGVLATLLLWHIIGATSSDDGYNLTVARVSSEAGYLANYYRYFGATEAPFDWYFTVLAKLASVSTAGVWMRIPATLAGIACWLIINHWVLRRLGPGTGGLSTNRVAVLTAGAMFLAAWLPFNNGLRPEPLIALGVLFTWVLVERAIALRRLASAATAAVVAILTATLAPQGLIAIAALLTGARAITQTIRRRRTTDGLLAPLLVLAASLSLITLVVFHSQTLATVGESARIKYKVGPTIACYQDFLRYYFLTVESNADGSMTRRFPVLVLLLCMFGVLVVLLRRSRVPGLASGPTWRLIGTTATSLLLLTFTPTKWAIQFGALAGLTGTFGAIAAFAFARISLHTRRNLTVYITALLFVLAWATAGINGWFGVSNYGVPWFDIQPVIAGHPVTSIFLTLSILTGLLAGGQHFRLDYAKHTEVKDTRRNRFLATTPLVVVATTMVLCEVGSLAKGAVARYPLYTTAKANLAALRSGLAPSVCAMADDVLTEPDPNAGMLQPVPGQIFGPTGPLGGMNPIGFKPEGVNDDLKSDPVVSKPGLVNSDASPNKPNVTFSDSAGTAGGKGPVGVNGSHVALPFGLDPDRTPVMGSYGENTLAASATSAWYQLPLHWKESIADRPLVVVSAAGAIWSYKEDGNFIYGQSLKLQWGVTRPDGIIQPLAQVMPIDIGPQPAWRNLRFPLTWAPPEANVARVVAYDPNLSPDQWLAFTPPRVPVLQTLQQLLGSQTPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSEAGGPFLFLQALLRTSTISTYLRDDWYRDWGSVEQYYRLVPADQAPEAVVKQGMITVPGWIRRGPIRALP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EmbA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

4 proteins show strong predicted evidence for PPIs

27 show intermediate predicted evidence for PPIs

158 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EmbA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.