embC
mL0106c
Probable integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 144115 – 147327
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0106c_embC_dna
GTGAGCGGCGCGGGAGCAAACTACTGGATCGCTCGCCTCCTTGCCGTGATCGCCGGCCTGCTCGGGGCCTTGCTAGCGATGGCAACCCCGTTCCTACCGGTCAACCAGAACACCGCCCAATTGAACTGGCCGCAGAACAGCACGTTCGAGAGCGTCGAGGCACCGCTGATCGGGTATGTAGCCACCGGACTGAACGTCACCGTGCCGTGTGCAGCCGCGGCCGGGCTGACTGGGCCGCAGAGCGCAGGCCAGACCGTGCTGTTGTCGACTGTGCCCAAACAGGCCCCGAAGGCCGTCGATCGGGGGCTACTCATACAGCGCGCCAACGACGACCTGGTGCTCGTGGTCCGCAACGTTCCGGTGGTCAGTGCCCCGATGAGCCAGGTGCTCAGCCCAGCCTGCCAACGCTTGACGTTCGCCGCGTACTTCGACAAGATCACTGCCGAGTTCGTCGGGTTGACGTACGGGCCCAATGCCGAGCATCCCGGTGTGCCATTGCGCGGCGAACGCAGCGGCTATGACTTCCGCCCACAGATCGTCGGGGTGTTCACCGATCTGTCCGGACCGATTCCGACAGGCCTAAACTTCTCCGCGACCATCGACACTCGCTACAGCAGCAGCCCCACACTTTTGAAGACGATCGCGATGATCCTCGGAGTGGTGCTTACTATAGTTGCTTTAGTCGCCCTTCATCTCCTTGACACCGCTGATGGCACTCAGCACCGGCGGTTACTACCGTCCCGATGGTGGTCCATCGGCTGTTTAGATGGCCTGGTCATCACCATACTAGCATGGTGGCATTTCGTTGGCGCCAACACATCCGACGATGGCTACATCTTGACGATGGCCCGAGTATCCGAGCATGCCGGCTACATGGCCAATTATTACCGGTGGTTCGGCACACCCGAGGCACCGTTCGGCTGGTACTACGACCTTCTGGCACTGTGGGCGCACGTGACTACCACCAGCGCCTGGATGCGGGTGCCGACCCTGGCTATGGCACTGACATGCTGGTGGCTAATCAGTCGGGAAGTCATTCCCCGACTGGGGCACGCCGCCAAGGCCAGCCGCGCCGCGGCGTGGACTGCGGCGGGCATGTTCCTCGCGGTGTGGTTGCCACTGGACAACGGCCTGCGACCGGAGCCAATCATCGCCCTGGGAATTCTGTTGACCTGGTGTTCGGTGGAGCGCGCGGTGGCCACCAGCCGGTTGCTGCCGGTGGCGGTCGCCTGCATTGTCGGTGCACTGACCCTATTCTCCGGGCCAACGGGTATCGCCTCAATTGGCGCACTGCTGGTCGCCGTCGGGCCATTGTTGACCATCCTGCAACGCCGCTCCAAGCAGTTTGGAGCGGTGCCGTTGGTGGCGCCCATCCTGGCTGCGTCCACGGTCACCGCGATTCTGATCTTCCGAGACCAGACGTTCGCCGGCGAGAGCCAGGCCAGCTTGCTCAAGCGCGCCGTCGGGCCCAGCCTGAAGTGGTTTGACGAGCACATCCGTTACGAACGACTGTTCATGGCCAGCCCCGACGGTTCGGTCGCCCGCCGCTTCGCCGTGCTGGCGTTGCTCGTAGCACTATCGGTGGCGGTGGCAATGTCGTTGCGCAAGGGTCGAATTCCGGGCCTTGCAGCCGGGCCCAGTCGACGCATCATCGGCATCACCGTCACCTCGTTTCTGGCGATGATGTTCACCCCAACCAAATGGACACACCACTTCGGAGTGTTCGCCGGGCTGGCCGGCTCACTAGGGGCACTAGCTGCGGTCGCAGTAGCCAGTGCGGCACTACGGTCCCGACGCAACCGTACCGTGTTCGCCGCTGTGGTGCTGTTCGTGGTGGCGTTGTCTTTCGCAAGCGTCAACGGCTGGTGGTACGTCTCCAATTTCGGTGTGCCATGGTCAAATTCGTTCCCAAAGCTGCGATGGTCTCTAACCACCGCCCTACTCGAGCTCACGGTGATAGTGCTGCTGTTGGCAGCATGGTTTCACTTCGTTGCTACCACCAACGGTTCTGCCAAAACCAGATTCGGAGTACGAATAGACAGAATCGTTCAGTCCCCAATAGCAATTGCGACCTGGTCACTGGTCATATTCGAGGTAGCATCACTAACCATGGCGATGATCGGCCAGTACCCGGCATGGACGGTGGGAAAGTCCAACCTGCAGGCGTTAACCGGACAAACCTGTGGACTGGCCGAAGAAGTTTTGGTCGAGCAGGATCCCAACGCCGGCATGTTGCTCCCGGTGTCCACCCCGGTAGCCGACGCACTAGGGTCGAGCTTAGCGGAAGCCTTCACAGCCAACGGAATTCCAGCCGACGTGTCAGCCGACCCAGTTATGGAACCCCCGGGCGACCGCAGTTTCGTCAAAGAAAACGGGATGACCACCGGCGGCGAAGCCGGCAACGAGGGTGGCACCAATGCCACACCAGGAATCAACGGCTCCCGCGCCCAGCTGCCCTACAACTTGGATCCGGCTCGCACACCGGTGTTGGGCAGCTGGCAGTCCGGCATTCAAGTGGTCGCCAGACTGCGGTCTGGCTGGTACCGACTACCAGCACGGGACAAGGCCGGTCCGTTGCTGGTCGTGAGTGCAGCAGGGCGCTTCGATCACCACGAAGTCAAACTGCAATGGGCCACCGATAGCGGAGCAGCAAGCGGACAGCCCGGTGGGGCATTCCAATTCTCTGATGTCGGGGCATCGCCGGCCTGGCGTAACCTACGGCTTCCCCTGTCGGCGATCCCGAGTATGGCGACCCAGATCCGCTTAGTCGCCGACGACGAAGATTTGGCGCCACAGCATTGGATTGCACTTACGCCACCACGGATTCCGCAGTTGCGCACCCTGCAGGATGTGGTCGGCTACCAGGACCCAGTATTCCTGGACTGGCTGGTGGGTCTGGCATTCCCCTGCCAACGGCCGTTCGACCATCAATATGGGGTCGACGAAACGCCGAAGTGGCGTATTCTTCCTGACCGATTCGGCGCCGAAGCCAACTCACCGGTTATGGATAATAACGGCGGTGGGCCGCTGGGCGTCACTGAGTTGCTGTTAAAGGCGACCACAGTAGCCAGCTACCTCAAAGACGACTGGTCACGCGACTGGGGTGCATTGCAGCGCTTGACGCCCTACTACCCTAACGCCCAGCCCGCTCGTTTGTCGCTAGGCACAACCACTCGCAGCGGTCTGTGGAACCCTGCACCACTCCGCCATTAG

Protein Sequence 

>ML0106c_EmbC_protein
VSGAGANYWIARLLAVIAGLLGALLAMATPFLPVNQNTAQLNWPQNSTFESVEAPLIGYVATGLNVTVPCAAAAGLTGPQSAGQTVLLSTVPKQAPKAVDRGLLIQRANDDLVLVVRNVPVVSAPMSQVLSPACQRLTFAAYFDKITAEFVGLTYGPNAEHPGVPLRGERSGYDFRPQIVGVFTDLSGPIPTGLNFSATIDTRYSSSPTLLKTIAMILGVVLTIVALVALHLLDTADGTQHRRLLPSRWWSIGCLDGLVITILAWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTPEAPFGWYYDLLALWAHVTTTSAWMRVPTLAMALTCWWLISREVIPRLGHAAKASRAAAWTAAGMFLAVWLPLDNGLRPEPIIALGILLTWCSVERAVATSRLLPVAVACIVGALTLFSGPTGIASIGALLVAVGPLLTILQRRSKQFGAVPLVAPILAASTVTAILIFRDQTFAGESQASLLKRAVGPSLKWFDEHIRYERLFMASPDGSVARRFAVLALLVALSVAVAMSLRKGRIPGLAAGPSRRIIGITVTSFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVASAALRSRRNRTVFAAVVLFVVALSFASVNGWWYVSNFGVPWSNSFPKLRWSLTTALLELTVIVLLLAAWFHFVATTNGSAKTRFGVRIDRIVQSPIAIATWSLVIFEVASLTMAMIGQYPAWTVGKSNLQALTGQTCGLAEEVLVEQDPNAGMLLPVSTPVADALGSSLAEAFTANGIPADVSADPVMEPPGDRSFVKENGMTTGGEAGNEGGTNATPGINGSRAQLPYNLDPARTPVLGSWQSGIQVVARLRSGWYRLPARDKAGPLLVVSAAGRFDHHEVKLQWATDSGAASGQPGGAFQFSDVGASPAWRNLRLPLSAIPSMATQIRLVADDEDLAPQHWIALTPPRIPQLRTLQDVVGYQDPVFLDWLVGLAFPCQRPFDHQYGVDETPKWRILPDRFGAEANSPVMDNNGGGPLGVTELLLKATTVASYLKDDWSRDWGALQRLTPYYPNAQPARLSLGTTTRSGLWNPAPLRH

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EmbC with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

3 proteins show strong predicted evidence for PPIs

16 show intermediate predicted evidence for PPIs

150 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EmbC

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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