mmpL7
mL0137c
Conserved transmembrane transport protein MmpL7
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 189253 – 191961
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0137c_mmpL7_dna
GTGTCAACCGACGACAGTCATAGGTCGCTCCGGCTAGCCAACCTCCTTGTCATCACCGCCTGGATCACAGCGGTAGTGATAGCCAACTTAATTTTCACGTTGACACAGGCGAAACTTCGTGATAAGAACTCGGTGCTCTTGCCGCAAGACACCATGACAGTCACCACAACCAACCAGATTGCGCAGGCTTTCCCAGGCACCGGCACGAACGCCATTGCCTACCTGGTGGTGGAAGGCAACAGGACACTTGAACCGGAAGACCAGCCTTACTACGACTCTGCCGTCAACGCCCTGCGCGCCGATACTCACGACGTGGGATCTGTCCTCGACTGGTGGTCGGATCCCCTCACCGCCCCGCTGGGGACCAGTCCCGACAGCCGCTCCGCAATAGCCTTGATCTGGTTGCAGGGCGAGGCGGGGACGACCCGAGCTCGGGCATCCCTCGGCGCTATCCGATCAGTGGTGCGCCAGTTACCGCCGAGTGAAGAGCTCCGCGCCCGTATCGTGGTCCCAGCGACCACTAACAACATGCCTATGGAGATGACTGCCTGGCAGGGCATGGCAATCGTGACCGCAGCGGCGGTGATCGCCATCTTATTCCTGCTGCGAGCGCGGCAAGCCATACGGATCGTGGTGATCATGCTGCTGACAGCCGACTTTTCGCTCGCGGCGGCTTGGCCGCTCGCCGCGGTGGTACAGAGACAAACTGGGGGGACCGTTTCGGTATTCTCTTGGAACTTGGCTGCAGTCCTGACGATCGGGACCATCACCGCTTCCACCCTGCTAGCGTCCAGGTCCTACACAGGTGATTCTGCCGCGCCCACTTGCCGCGCCCACTTGCCCGCATTGGCACTGCTCGGGGCGTGTGTCGCATTGCTCACCGGTACATTACTGCTTGCCCGAACACCGGCACTACACAGCGTCGGCACCGTAGCACTGGGTGTCGTTGTGGCACTTGCAGCTTCGTTGACACTGCTGCCTACGCTGATCAAGCTCGCAGGACCAAGTGGGCAAATATCACCACAGGTGAACGGCAATACCTGGACACGTCGGTTGTTAGTACCCAACTTCTCTAGTCCGGCACGCCTCACCGCCGTGGTGCTGGCCACCTGCGCACTACCAGTCATCGGGATGCGGTTGGGTCTGGCCGAGGACCATACCGCGCAAAGTGGCACACAGATCCTCCCGGGCAATCTGCTACCCGACATTCTGCTCATCAAATCCGCCCGGGACCTCAGGGATCCCGCGGCGCTTATCGCCATCGACCAAGTCAGTCACCGTCTGATGGAGATTCCCGGCGTACGCAAGGTGGAGTCGGCGGCATGGCCGGCTGGTGTACCGTGGAACGACGCCTCGCTCAGCTCCGCGGCGGGAAGGCTCGCCGATCAGATGAGTCAGCAGGCCGGGTCGTTCGTGCCGGCAGTGACTGCGATCAAACAAATGAAGACCATGATCGATCAGATGAGCAGCACCGTGGACGAACTGGAAAGCACCGTCAATGTGGCTCTGGCCGGGGCCCACCAAGTGCAACAGTACCTCAACCCGGTGCTCTCCGCCGCACGGAACATTAAAAGCAAAACCGCTGAATTTTCGGGATACCTGGACACAGTCCGCGGCTGGGTCGTAAGCGTTACAAACTGTCCCAACGACGTATTGTGTTCGGCCATGCGCAAGGTCATTGAACCATATGACAAAGTGGCCGCCAGCATGGACCAACTGTCCAATGGTGTCGACCGTATCTCGGCGATATCGGACCAAACAATAAGCTCCTTCAACGAAGCACCGCACATGGTGGCGCAGATGCGGTCGGCGCTGAAGCAAGCACGCTCCTTCATACCCAGGCTGGAATCCACCATCCAGGAACTCATGCCGCAAATAGCGCAAGCATCGGCGATGCTGAAAAATCTCAGTAGAGACTTTGCTGATACCGGTGAAGGCGGCTTCCATCTACCCATGAAGGAGCTGATGAGTTCATCCTACCAGCACGTACGAGAATCGATGTTCTCGTCAGACGGAACAGCGACCCGCCTGGTCGTCTACACTAATGAGCATAACCCGGGTCTTGATACCGCGGCGCGTGCGCAGCAGCTCGAAATCGCCGCAGGCAAGGCGATGAAATACGGAAGCCTCGTTGACAGCCGGATCACGCTAGGTGGGGCCGCACAAGTAGCCGTAGCCGCTCGTGCTGCCCTTACCCACGACGCTGTGCTGTTGGCAGGTATGCTATTTGCAGTAGTGGCCCTGGCCAGCATGTGGGTCAGCGCTGGCAGTGGAGTTGCGGTTGGCTTAGGCGTGCTAGCCGCCTACCTCGGCGGGTTGGGAATCTCGGTTGCGCTGTGGCAACACATCCTGGGTCACGAACTGCAGGCCTCGGTCCCACTGGTATCCTTCGCCATCCTAGCTCCGTGTGGGGTACTGTATCTGGTTACCAGTCTCGAGGCCGCTCGAGTCTCCGCCGAGGCGAAGACTGCGGCGACCGTGTCCGTGCGGCGCGCGGTTGTACCGCTGACTGTGCTCGGCGCTATATTCGGCGCCGGACTGGTGGTGGCGGAAGCTTCCTTCAGTGCGCTCAGCCAAGTCGGTACGGTTCTGGTGATCGCGCTGGGCGCGCTCACCAAGGTGGAACAAGTTTTGATTTCCTACCATGCCGAAGCGGCCATGCCAGCCTGGTCAAAACTGCCGAGCCGATTAAGCGGTGGCCCTAACTAA

Protein Sequence 

>ML0137c_MmpL7_protein
VSTDDSHRSLRLANLLVITAWITAVVIANLIFTLTQAKLRDKNSVLLPQDTMTVTTTNQIAQAFPGTGTNAIAYLVVEGNRTLEPEDQPYYDSAVNALRADTHDVGSVLDWWSDPLTAPLGTSPDSRSAIALIWLQGEAGTTRARASLGAIRSVVRQLPPSEELRARIVVPATTNNMPMEMTAWQGMAIVTAAAVIAILFLLRARQAIRIVVIMLLTADFSLAAAWPLAAVVQRQTGGTVSVFSWNLAAVLTIGTITASTLLASRSYTGDSAAPTCRAHLPALALLGACVALLTGTLLLARTPALHSVGTVALGVVVALAASLTLLPTLIKLAGPSGQISPQVNGNTWTRRLLVPNFSSPARLTAVVLATCALPVIGMRLGLAEDHTAQSGTQILPGNLLPDILLIKSARDLRDPAALIAIDQVSHRLMEIPGVRKVESAAWPAGVPWNDASLSSAAGRLADQMSQQAGSFVPAVTAIKQMKTMIDQMSSTVDELESTVNVALAGAHQVQQYLNPVLSAARNIKSKTAEFSGYLDTVRGWVVSVTNCPNDVLCSAMRKVIEPYDKVAASMDQLSNGVDRISAISDQTISSFNEAPHMVAQMRSALKQARSFIPRLESTIQELMPQIAQASAMLKNLSRDFADTGEGGFHLPMKELMSSSYQHVRESMFSSDGTATRLVVYTNEHNPGLDTAARAQQLEIAAGKAMKYGSLVDSRITLGGAAQVAVAARAALTHDAVLLAGMLFAVVALASMWVSAGSGVAVGLGVLAAYLGGLGISVALWQHILGHELQASVPLVSFAILAPCGVLYLVTSLEAARVSAEAKTAATVSVRRAVVPLTVLGAIFGAGLVVAEASFSALSQVGTVLVIALGALTKVEQVLISYHAEAAMPAWSKLPSRLSGGPN

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MmpL7 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

47 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MmpL7

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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