ML0227
mL0227
Probable conserved secreted or membrane protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 298516 – 298992
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0227_ML0227_dna
ATGGGACCGACCCGGAAACGTGACCTGACGGCCGCGATGATTGGCGCTGCGGTAGTAGGTTATCTGCTGGTGCTTGTGCTGTACCGGTGGTTTCCACCCATCACCGTGTGGACTGGTCTGTCGTTGCTTGCGGTTGCTATCCCCGAGGCGTTGTGGGCGCGCTACGTGCGGACCAAGATCAGCGATGGTGAGATCGGCGATGGCCCCGGTTGGCTGCACCCGCTAGCGGTAGCACACAGCCTGATGGTTGCCAAGGCGTCGGCCTGGGTGGGTGCGCTAGTGCTGGGTTGGTGGGTCGGTGTATTGGTGTACTTTTTGCCGCGGTGGCCGTGGCTGCGGGTTGCTGACAAGGACACCTCTGGAACGGTCGTGGCGGCTCTCAGCGCTCTGGCGTTACTAGTTGCAGCCTTGTGGCTGCAACATTGCTGCAAATCTCCGCAAGATCCCACCGAGCACGGCGAGGGTGCCGAAAATTAG

Protein Sequence 

>ML0227_ML0227_protein
MGPTRKRDLTAAMIGAAVVGYLLVLVLYRWFPPITVWTGLSLLAVAIPEALWARYVRTKISDGEIGDGPGWLHPLAVAHSLMVAKASAWVGALVLGWWVGVLVYFLPRWPWLRVADKDTSGTVVAALSALALLVAALWLQHCCKSPQDPTEHGEGAEN

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML0227 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

7 show intermediate predicted evidence for PPIs

80 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML0227

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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