eno
mL0255
Probable enolase Eno (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 333751 – 335094
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0255_eno_dna
TTGAGCCCACCCACAGGACGTCCACGTCTCAGCCATGACTATAAGGAGAACTTGGTGCCGGTTATCGAGCAGGTCGGGGCCCGCGAGATCCTCGATTCCCGCGGCAACCCCACGGTCGAAGTCGAGGTGGTGCTGATTGACGGAACCTTCGCCCGCGCAGCGGTGCCTTCGGGCGCATCGACCGGCGAGTATGAGGCCGTCGAGTTACGTGACGGCGACGGTCGTTACGGTGGCAAGGGTGTGAAAAGGGCCGTGGATGCTGTGCTCGACGAGATCGGTCCAGTGGTGATCGGCCTCAACGCCAATGACCAGCGGCTGATCGATCAGGAGCTGCTGGACCTCGACGGCACCCCCGACAAGTCCCGATTGGGTGGTAACGCGATCCTGGGTGTCTCGCTGGCCGTCGCCAAGGCAGCCGCCGATTCAGCGGAATTGCCGCTGTTCCGTTATATTGGAGGGTCTAACGCACATATCCTTCCGGTGCCTATGATGAACATTCTCAACGGCGGCGCGCACGCCGACACTGCTGTTGATGTGCAGGAGTTCATGGTGGCACCGATCGGGGCACCCAGTTTCGTTGAGGCGCTGCGTTGGGGCGCCGAGGTATATCACGCTCTCAAATCGGTTCTGAAGAAAAAAGGGTTAAGCACCGGCCTGGGTGATGAGGGTGGCTTTGCCCCTGAAGTGGCCGGAACCACCGCGGCGCTGGACTTGGTCACCTTAGCTATTGAAGCGGCGGGTTTTAAGCCGGGTGCCGATGTGGCATTGGCCCTTGATGCGGCAGCCACCGAGTTCTACACGGACGGCATCGGCTACCATTTCGAGGGCATGACCCACACTGCCGACCAGATGACTGAGTTTTATGCCGACTTGCTGGGTTCATACCCACTGGTGTCCATCGAAGATCCGCTGTCCGAAGATGATTGGGACGGTTGGGCTGCTCTGACGGCGTCGATAGGGGAACAGGTGCAGATCGTCGGGGACGACATCTTTGCCACCAATCCTGAGAGACTGGAGGAGGGCATCGGTCGCGGTGTGGCAAACGCGTTGCTGGTCAAGGTGAACCAGATAGGCACGTTGACCGAGACGCTCGAAGCTGTTGCGTTGGCACATCACAGCGGATATCGCACGATGATCAGCCACCGCAGTGGCGAGACCGAGGACACGATGATCGCTGACCTGGTCGTGGCTCTCGGTAGCGGGCAAATTAAGACGGGAGCGCCCGCCCGCAGTGAGCGCGTCGCTAAATATAACCAGCTGCTGCGGATTGAAGAGGAGCTCGGCGACGCCGCCCGCTATGCCGGCGATCTGGCATTTCTGCGATACGTCGTGGAAACGAGATAA

Protein Sequence 

>ML0255_Eno_protein
LSPPTGRPRLSHDYKENLVPVIEQVGAREILDSRGNPTVEVEVVLIDGTFARAAVPSGASTGEYEAVELRDGDGRYGGKGVKRAVDAVLDEIGPVVIGLNANDQRLIDQELLDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRYIGGSNAHILPVPMMNILNGGAHADTAVDVQEFMVAPIGAPSFVEALRWGAEVYHALKSVLKKKGLSTGLGDEGGFAPEVAGTTAALDLVTLAIEAAGFKPGADVALALDAAATEFYTDGIGYHFEGMTHTADQMTEFYADLLGSYPLVSIEDPLSEDDWDGWAALTASIGEQVQIVGDDIFATNPERLEEGIGRGVANALLVKVNQIGTLTETLEAVALAHHSGYRTMISHRSGETEDTMIADLVVALGSGQIKTGAPARSERVAKYNQLLRIEEELGDAARYAGDLAFLRYVVETR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Eno with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

17 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Eno

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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