thiO
mL0299c
Possible thiamine biosynthesis oxidoreductase ThiO
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 381655 – 382677
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0299c_thiO_dna
ATGCCGTCAGGCCCACCCGCGGGGTCGCTGGCCGTTATCGGCGGCGGCGTCATCGGGCTATCGGTGGCACGCCGCGCAGTGCAGGCCGGGTGGTCCGTGCGTGTACACCGGACCCACGAGCAAGGTGCGTCCTGGGTTGCCGGGGGCATGCTGGCCCCGCACAGCGAAGGCCGGCCCGGTGAGGAACAGTTGTTGCAGCTGGGCCTGAGGTCGCTACGGCTGTGGCACGAAGGTGGATTTACCGACAGGCTGGCTCCGGAGGTTATTACCGCGCGTGAGTCGCTGGTGGTGGCCGTCGACCAGGCTGATGTCGCTGACCTACGCACGGTTGCGGACTGGTTGTCCACGCAAGGCCACCCGGTGATCTGGGAATCTGCTGCCCGCGACATAGAACCCCTACTGGCACAAGGCATCCGACATGGTTTCTGGGCGCCTAACGAACTAGCAGTGGACAACCGGGCCTTGCTCGCCGGGCTGTGCTTGGACTGTGAGCGTCTAGGGGTGCGATGGGCCTCGCCGGTCAACGATCTGTCCTGTGTCAACGCAGACGCGGTAGTGATTGCCAATGGCATTGGCGCTCCTGCGCTGTGGCCCGGCCTGCCGGTCCGTCCGGTCAAGGGGGAAGTGCTGCGTTTGCGCTGGCGAAATGGTTGTATGTCATTGCTAAAGAGGTTAATTCGAGCCCATGTGCACGGCAGGCAGGTGTACCTGGTTCCGCGTGCGGACGGAGTAGTCGTCGGTGCCACCCAGTACGAACACGGTTACGATACCGCCCCGGTCGTGTCGGGCGTGCGTGATCTGCTTGACGATGCGTGTGCCGTGCTGCCAACGTTGGGCGAGTACGAGCTGGCTGAGTGCGCGGCTGGACTGCGCCCAACGACACCGAATAACCTGCCACTTGTGCACCGCCTAGATAACCGTACGCTGGTAGCTGCCGGCCATGGCAGATCGGGATTTCTGTTGGCACCATGGACAGCTGAGCAGATCATGTTCGAACTTGCCGCGGTCGGAGCCCAAGCGTGA

Protein Sequence 

>ML0299c_ThiO_protein
MPSGPPAGSLAVIGGGVIGLSVARRAVQAGWSVRVHRTHEQGASWVAGGMLAPHSEGRPGEEQLLQLGLRSLRLWHEGGFTDRLAPEVITARESLVVAVDQADVADLRTVADWLSTQGHPVIWESAARDIEPLLAQGIRHGFWAPNELAVDNRALLAGLCLDCERLGVRWASPVNDLSCVNADAVVIANGIGAPALWPGLPVRPVKGEVLRLRWRNGCMSLLKRLIRAHVHGRQVYLVPRADGVVVGATQYEHGYDTAPVVSGVRDLLDDACAVLPTLGEYELAECAAGLRPTTPNNLPLVHRLDNRTLVAAGHGRSGFLLAPWTAEQIMFELAAVGAQA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ThiO with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

26 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ThiO

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.