pknG
mL0304
Probable serine-threonine protein kinase PknG (protein kinase G) (STPK G)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 386630 – 388933
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0304_pknG_dna
TGGCCGAGTCCATGAAGAGAGAACACATGGACCACGACACCGAAGACGTGGGCCAGGCCGCCCAGCGGGCAGACCCGCCGTCCGGCACAACGGAAGGGCGCCTGCAGTCCACCCAGGCGATATTCCGGCCTAATTTTGATGACGACGATGACCTTTTGCATATCTCTGTCCCCAGCGTGGACACCGAGCCGCAAGACCGTATAACGCCGGCGACCAGGGTATTACCGCCGATCAGACAGCTTGGCGGCGGACTCGTGGAAATCCGCCGGGTGCGCGATATTGATCCGCTTGAGGCCTTGATGACCAATCCTGTGGTGCCGGAATCCAAGCGGTTCTGCTGGAATTGCGGTCGGCCGGTCGGCCGGTCCGAGTTGGAGGGTCAGGAGGCTGATGGCGCCCAAGGGGCTAAAGAGGGTTGGTGCCCATACTGCGGCAGCCCGTATTCGTTCTTACCTCAGCTGAGTCCCGGAGACATCGTCGCCGGTCAGTACGAGGTCAAGGGTTGCATCGCGCACGGCGGGTTGGGCTGGGTCTATCTGGCGTTCGACCATAACGTCAACGACCGGCCGGTGGTACTCAAGGGCCTGGTTCACTCCGGTGACGCCGAGGCGCAGGCGAGCGCAGTGGCCGAACGGCAATTCCTCGCCGAGGTGGTGCACCCACAGATCGTTCAGATCTTCAACTTTGTGGAGCACAAAGATACATCCGGGGATCCGGTCGGCTACATTGTAATGGAATACATCGGTGGACGATCGCTGAAGCGGGGCTCGAAAAAGGGCAACGTCGAGAAACTTCCGGTCGCCGAGGCAATCGCCTACCTGCTGGAAATCCTGCCCGCGCTAAGCTATTTGCATTCCATCGGCTTGGTCTACAACGACCTGAAGCCAGAGAACATCATGCTCACTGAAGAGCAGCTCAAATTGATTGACCTAGGCGCGGTGTCGCGGATCAACTCGTTCGGTTGCATCTATGGTACACCCGGCTATCAGGCGCCAGAGATCGTGCGTACCGGACCGACGGTGGCCACCGACATCTACACCGTGGGCCGCACACTCGCGGCGCTCACGTTGAACCTGCGCACCCGCAACGGCCGCTACATGGACGGGCTGCCCGAAGACGATCCGGTGTTGACTACTTACGACTCTTTTGCTCGGTTGCTGCACCGTGCCATCAACCCCGACCCACGGCGCCGTTTCAGCTCCGCCGAGGAGATGTCCGCGCAGCTGATGGGTGTGTTGCGGGAAGTGGTCGCCCAAGACACTGGGGTGCCGCGGGCCGGCCTATCAACCATCTTCAGCCCGAGTCGCTCGACATTCGGTGTGGACCTGCTGGTAGCCCACACCGATGTTTATCTAGACGGCAGGTTGCATTCGGAGAAGCTCACCGCCAAAGATATCGTGACGGCGCTGCAGGTTCCACTGGTTGATCCGACCGACGTGGCCGCCCCGGTACTGCAGGCGACGGTGCTCTCCCAGCCGGTGCAGACACTGGACTCGCTGCGAGCAGCCCGGCACGGCATGCTGGATGCGCAGGGTATCGACTTGGCTGAGTCGGTTGAACTGCCGCTGATGGAAGTCCGTGCGCTGCTGGACCTGGGTGATGTGGTCAAGGCCAACCGGAAACTCGACGACCTGGCCGATCGGGTTAGCTGCCAATGGCGATTGGTCTGGTACCGTGCTGTCGCCGATCTCCTCACCGGCGATTACGCCTCGGCCACCAAACATTTCACCGAGGTGCTGAATACCTTTCCCGGCGAGCTGGCACCCAAGCTCGCGCTAGCCGCCACCGCCGAACTGGCTGGCGAAAGCGACGAGCATAAGTTTTACCGTACTGTGTGGCATACCAATGACGGCGTGGTATCAGCGGCTTTCGGGCTGGCGAGATTCCAATCAGCCGAGGGCGACCGAACCGGTGCGGTGTGCACCCTTGATGAAGTGCCTCCTACCTCGCGCCATTTCACCACCGCGCGCCTGACCAGTGCGGTGACACTGCTGTCCGGCCGATCCACGAACGAAATCACCGAACAGCAGATCCGTGACGCCGCCAGGCGAGTGGAGACGCTGCCGCCCACCGAACCACGTGTGCTGCAGATCCGCGCTCTAGTCCTGGGGTGCGCGATGGACTGGCTAGCCGATAACCAGGCCAGCGCCAATCACATCCTAGGTTTTCCGTTCACGAAACACGGATTGCGACTAGGTGTTGAGGCCTCGCTACGCAGCCTGGCCCGAGTCGCGCCCACCCAACGGCACCGCTATACTTTGGTGGACATGGCCAACAAGGTGCGGCCCACGAGTACATTATAGT

Protein Sequence 

>ML0304_PknG_protein
WPSP_RENTWTTTPKTWARPPSGQTRRPAQRKGACSPPRRYSGLILMTTMTFCISLSPAWTPSRKTV_RRRPGYYRRSDSLAADSWKSAGCAILIRLRP__PILWCRNPSGSAGIAVGRSAGPSWRVRRLMAPKGLKRVGAHTAAARIRSYLS_VPETSSPVSTRSRVASRTAGWAGSIWRSTITSTTGRWYSRAWFTPVTPRRRRAQWPNGNSSPRWCTHRSFRSSTLWSTKIHPGIRSATL_WNTSVDDR_SGARKRATSRNFRSPRQSPTCWKSCPR_AICIPSAWSTTT_SQRTSCSLKSSSN_LT_ARCRGSTRSVASMVHPAIRRQRSCVPDRRWPPTSTPWAAHSRRSR_TCAPATAATWTGCPKTIRC_LLTTLLLGCCTVPSTPTHGAVSAPPRRCPRS_WVCCGKWSPKTLGCRGPAYQPSSARVARHSVWTCW_PTPMFI_TAGCIRRSSPPKIS_RRCRFHWLIRPTWPPRYCRRRCSPSRCRHWTRCEQPGTACWMRRVSTWLSRLNCR_WKSVRCWTWVMWSRPTGNSTTWPIGLAANGDWSGTVLSPISSPAITPRPPNISPRC_IPFPASWHPSSR_PPPPNWLAKATSISFTVLCGIPMTAWYQRLSGWRDSNQPRATEPVRCAPLMKCLLPRAISPPRA_PVR_HCCPADPRTKSPNSRSVTPPGEWRRCRPPNHVCCRSAL_SWGARWTG_PITRPAPITS_VFRSRNTDCD_VLRPRYAAWPESRPPNGTAILWWTWPTRCGPRVHYS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PknG with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

64 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PknG

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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