groEL2
mL0317
65 kDa chaperonin 2 GroEL2 (Protein Cpn60-2) (groEL protein 2) (65 kDa antigen) (Heat shock protein 65) (Cell wall protein A) (Antigen A).
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 405519 – 407144
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0317_groEL2_dna
TGGCCAAGACAATTGCGTACGACGAAGAGGCCCGTCGCGGCCTCGAGCGGGGCTTGAACAGCCTCGCCGACGCGGTAAAGGTGACGTTGGGTCCGAAGGGGCGCAACGTCGTTCTAGAGAAGAAGTGGGGTGCTCCCACGATCACCAACGATGGCGTGTCCATCGCCAAGGAGATCGAGCTGGAGGACCCGTACGAGAAGATTGGCGCTGAGTTGGTCAAGGAAGTCGCCAAGAAGACAGATGACGTCGCCGGTGATGGCACCACGACGGCCACCGTGCTGGCCCAGGCATTGGTCAAAGAGGGCCTACGCAACGTCGCGGCCGGCGCCAACCCGCTAGGTCTCAAGCGTGGCATCGAGAAAGCTGTCGATAAGGTAACTGAGACTCTGCTCAAGGACGCTAAGGAGGTCGAAACCAAGGAACAAATTGCTGCCACTGCAGCGATTTCGGCGGGTGACCAGTCGATCGGTGATCTGATCGCCGAGGCGATGGACAAGGTTGGCAACGAGGGTGTTATCACCGTCGAGGAATCCAACACCTTCGGTCTGCAGCTCGAGCTCACCGAGGGAATGCGGTTCGACAAGGGCTACATTTCGGGCTACTTCGTCACCGACGCCGAGCGTCAGGAAGCTGTCCTAGAGGAGCCCTACATCCTTCTGGTCAGCTCCAAAGTGTCTACCGTCAAGGACCTGCTGCCGCTGCTAGAGAAGGTCATCCAGGCCGGCAAGTCGCTGCTGATCATTGCTGAGGATGTCGAGGGTGAGGCGTTGTCTACCCTGGTCGTCAACAAGATCCGTGGCACTTTCAAGTCGGTGGCGGTCAAAGCTCCTGGCTTTGGTGACCGCCGCAAGGCAATGTTGCAAGACATGGCCATTCTCACCGGAGCCCAGGTCATCAGCGAGGAGGTCGGTCTCACATTGGAGAACACCGATCTGTCATTGCTGGGCAAGGCCCGCAAGGTGGTTATGACCAAGGACGAAACCACCATCGTCGAGGGTGCCGGTGACACCGACGCCATCGCCGGGCGAGTGGCTCAGATCCGTACCGAGATCGAGAACAGTGACTCTGACTATGACCGCGAGAAACTGCAGGAACGCCTGGCTAAGTTGGCCGGTGGTGTTGCGGTGATCAAGGCCGGTGCTGCCACTGAGGTGGAGCTCAAGGAGCGCAAGCACCGCATCGAGGACGCAGTCCGCAACGCCAAGGCCGCGGTGGAGGAGGGGATCGTCGCCGGCGGCGGTGTGACTCTGCTACAGGCTGCTCCGGCTCTGGACAAGCTGAAGCTGACCGGTGACGAGGCGACCGGTGCCAATATTGTCAAGGTGGCGTTGGAAGCTCCGCTCAAGCAGATCGCCTTCAATTCCGGGATGGAGCCCGGCGTGGTGGCCGAAAAGGTGCGTAACCTTTCAGTGGGTCACGGCCTGAACGCCGCCACCGGTGAGTACGAGGACCTGCTCAAGGCCGGCGTTGCCGACCCGGTGAAGGTTACACGTTCTGCGCTGCAGAACGCAGCGTCCATCGCCGGCCTGTTCCTTACTACGGAGGCCGTCGTCGCCGACAAGCCGGAGAAGACGGCAGCTCCGGCGAGCGACCCGACCGGTGGCATGGGTGGTATGGACTTCTGAC

Protein Sequence 

>ML0317_GroEL2_protein
WPRQLRTTKRPVAASSGA_TASPTR_R_RWVRRGATSF_RRSGVLPRSPTMACPSPRRSSWRTRTRRLALSWSRKSPRRQMTSPVMAPRRPPCWPRHWSKRAYATSRPAPTR_VSSVASRKLSIR_LRLCSRTLRRSKPRNKLLPLQRFRRVTSRSVI_SPRRWTRLATRVLSPSRNPTPSVCSSSSPRECGSTRATFRATSSPTPSVRKLS_RSPTSFWSAPKCLPSRTCCRC_RRSSRPASRC_SLLRMSRVRRCLPWSSTRSVALSSRWRSKLLALVTAARQCCKTWPFSPEPRSSARRSVSHWRTPICHCWARPARWL_PRTKPPSSRVPVTPTPSPGEWLRSVPRSRTVTLTMTARNCRNAWLSWPVVLR_SRPVLPLRWSSRSASTASRTQSATPRPRWRRGSSPAAV_LCYRLLRLWTS_S_PVTRRPVPILSRWRWKLRSSRSPSIPGWSPAWWPKRCVTFQWVTA_TPPPVSTRTCSRPALPTR_RLHVLRCRTQRPSPACSLLRRPSSPTSRRRRQLRRATRPVAWVVWTSD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GroEL2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

39 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GroEL2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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