ilvX
mL0354
Probable acetohydroxyacid synthase IlvX (acetolactate synthase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 447415 – 448962
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0354_ilvX_dna
TGAACGGTGCTCAGGCCATGATCAGTACCCTGGTCGACGGTGGTGTCGATGTGTGCTTCGCCAATCCCGGCACCTCGGAGATGCACTTCGTGGCCGCACTGGACACCGTTGCCGGAATGCGTGGCGTGCTAACCCTTTTCGAAGGTGTGGCCACTGGTGCGGCCGACGGCTACGCTCGTATAGCTGGCCGGCCGGCAGTGGTGCTGCTGCACCTGGGTCCCGGATTAGGGAACGGCCTGGCTAACCTGCACAACGCGCGCCGCGCACGGGTGCCCATGGTGGTGGTCGTCGGCGACCATGCCACCTATCACAAGAAGTATGATGCCCCACTGGAATCCGACATCGACGCTCTGGCAGGAACCGTTTCAGGATGGCTGCACCGGACAATGGACACCGCCGACGTTGGGGTCGACGCAGCGGAGGCGATCTCTGCCAGCCTGGTGGGCTCGCAGATCTCGACGCTGATCCTGCCCGCGGACGTATCCTGGTCTGACGGCGCCATTCCCGCCGCGTCGGTGTCAGACCAGCCAGCCAGTGCCGGTGTCGACGTGGGGGCGGTTCGCACGGCCCTGGAATCGGGAGAACCCACGGTGATTTTGATCGGTGCAGACGCCACCGGCTGGTCGGGGTTGGCAGCGGTCGCGCGGATCGGTGCGGCGACCGGCGCCCGCTGGTTCTGCGAGACGTTCCCGGCCCGATTGGAGCGGGGCGCTGGTGTCCCTGCTGTCGAACGACTCGCCTACTTTGCCGAGGTCGCCGCGGCTCAGCTGGACGGTGCCAAGCATCTAGTGCTGGCCGGTGCCCAGTCGCCGGTGTCGTTCTTTGCCTACCCTGGCATGCCTAGTGACTTGGTACCAGCCGGCTGTGAGGTGCACGTGCTTGCCGAGCACGGCGGTGCCGCTTACGCGCTAAACGCATTGGCTGACGAGGTGGCATCCGGGACCGCTGCGCCGGTGGTGGCCGCATCGCGCCCGCAGCTGCCGTCAGGTCCGCTGACCTCTGGGGCGGCGGCTAACGTGATTGGCGCGCTGCTGCCCGAACGGGCGATTGTCGTCGACGAATCGAATACCTCAGGGGTGCTGCTAGCCGCGGCTACCGCTGGAGCACCGGCCCATGATTGGCTGACTCTGACCGGCGGGGCGATCGGTCACGGCATCCCGGCCTCGGTGGGTGCCGCGGTGGCCGCCCCCGACCGCCCTGTGCTGTGCCTGGAATCCGACGGGTCGGCGATGTACACGATTTCGGGGTTGTGGACTCAAGCACGGGAAAACCTCGACGTAACCACAATAATCTACAACAACGGTGCTTACAACATTCTGCGGATTGAGTTGCAACGGATGGGTGCCGGGTCGACGCCTGGCCCCAAAGCGCTGAGTCTGCTCGATTTATCTAGCCCTACAATGGATTTCGTTAAGATCGCGGAGGGTATGGGAGTTTCTGCTCGTCGTGTCAATACCACAGAGGGGTTGGCCGATGCCCTGCGCCTGGCCTTCACTGAACCCGGACCGCACCTGATCGACACGGTAGTGCCATCAATCGTGGGGTGAC

Protein Sequence 

>ML0354_IlvX_protein
TVLRP_SVPWSTVVSMCASPIPAPRRCTSWPHWTPLPECVAC_PFSKVWPLVRPTATLV_LAGRQWCCCTWVPD_GTAWLTCTTRAAHGCPWWWSSATMPPITRSMMPHWNPTSTLWQEPFQDGCTGQWTPPTLGSTQRRRSLPAWWARRSRR_SCPRTYPGLTAPFPPRRCQTSQPVPVSTWGRFARPWNRENPR_F_SVQTPPAGRGWQRSRGSVRRPAPAGSARRSRPDWSGALVSLLSNDSPTLPRSPRLSWTVPSI_CWPVPSRRCRSLPTLACLVTWYQPAVRCTCLPSTAVPLTR_THWLTRWHPGPLRRWWPHRARSCRQVR_PLGRRLT_LARCCPNGRLSSTNRIPQGCC_PRLPLEHRPMIG_L_PAGRSVTASRPRWVPRWPPPTALCCAWNPTGRRCTRFRGCGLKHGKTST_PQ_STTTVLTTFCGLSCNGWVPGRRLAPKR_VCSIYLALQWISLRSRRVWEFLLVVSIPQRGWPMPCAWPSLNPDRT_STR_CHQSWGD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding IlvX with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

15 show weak predicted evidence for PPIs

View all pooled AlphaFold results for IlvX

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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