glmS
mL0371
Probable glucosamine-fructose-6-phosphate aminotransferase GlmS (Hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (Glucosamine-6-phosphate synthase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 462980 – 464857
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0371_glmS_dna
TGTGTGGACTTGTCGGCTACGTCGGGCAGCGCCCTGCCTGCGGGGTCGTCATGGATGCGCTGCGCAGGATGGAGTACCGCGGCTACGACTCGTCGGGAATCGCGCTGATCAACGGCAGTGCCAAATCGGGCAATCTGACCGTTCGTCGTCGTGCTGGTCGACTTTCCAATTTGGAGTCGGTGTTGGCGGAGATGGTTCCGGCGTCGCTGGCCGGCAACGTCGGCCTCGGCCATATCCGGTGGGCCACCCATGGTCGCCCCACCGACCGCAACGCGCATCCGCACCGCGACGCCACCGGCAAGATCGCCGTCGTCCACAACGGCATCATCGAGAATTTCCCCTCCCTTCGCCATGAGTTGGAGATCGCCGGAGTAGAGTTCGTCAGCGACACCGACACCGAGGTAGCTGTGCATTTGGTGGCACAGGCTTACTGCGCTGGCGAGACGGCCGGTGATTTCGTCGGGTCCGTGCTGGCGGTGCTGCGCCGGCTACAGGGCCACTTCACTCTGGTGTTCGCCAACGCCGACGAGCCCGGTACCATTGTGGCCGCGCGCCGCTCCACCCCGCTAGTGCTCGGGATCGGCGACGGGGAGATGTTCGTCGGTTCCGACGTGGCCGCGTTCATCGAACACACCCGGCAGGCGGTCGAGCTTGGTCAGGACCAGGCTGTGGTGATCACTGCAGATGGTTACCGAATCAGCGACTTCGATGGCAACGATGACGCTGTAAACGCTCGCACATTTCATATCGACTGGGACCTGGCCGCTGCCGAAAAGGGCGGCTACGAGTACTTCATGCTCAAGGAAATCGCTGAGCAGCCCGACGCGGTAGTCGACACGCTACTTGGGCATTTCACTGGTGGACGGATTGTGCTCGACGAACAGCGATTGAGCGATCAGGAACTCCGCGAGATCGATAAGGTGTTTGTGGTCGCTTGCGGTACTGCCTATCATTCCGGCTTGTTGGCCAAATATACGATCGAGCACTGGACGCGGCTGCCTGTTGAGGTGGAGCTAGCCAGCGAATTTCGCTACCGGGATCCTGTTCTGGACCGCAGCACACTGGTGGTAGCCATTTCGCAGTCCGGTGAAACCGCTGATACTTTAGAAGCTGTCCGGCACGCTAAAGAGCAGAAGGCCAAGGTGCTGGCGATTTGCAACACCAACGGCTCCCAAATCCCACGTGAGTGCGACGCGGTGCTGTATACTCGCGCTGGCCCGGAGATCGGCGTCGCCTCAACGAAAACCTTTCTGGCTCAGGTCGCCGCCAACTACCTCCTTGGGCTGGCGTTGGCGCAGGCCCGCGGCACTAAGTACCCCGATGAGGTGCAGCGCGAGTACCGCGAGCTGGAAGCGATGCCCGACCTGGTGGCCCGGGTCATCGCGGGGATGGGCCCCGTGGCCGATTTGGCTTACCGGTTCGCTCAGTCGACGACCGTGCTGTTCCTGGGTCGCCATGTCGGGTACCCGGTGGCGTTGGAAGGTGCGCTGAAACTCAAGGAATTGGCCTACATGCACGCCGAGGGGTTCGCCGCCGGCGAGCTCAAGCACGGACCCATCGCGCTGATCGAAGAAAACCTGCCGGTAATCGTCGTCATGCCCTCGCCCAAGGGATCGGCGATGCTGCATGCTAAGCTGCTGAGCAACATTCGTGAAATTCAGACCCGCGGAGCGGTGACCATTGTGATCGCGGAGGAAGGCGACGACACGGTACGTCTCTACGCCGATCACCTGATCGAACTCCCCGCGGTGTCAACACTTTTGCAGCCGCTGCTGTCGACCATCCCGCTGCAGGTGTTCGCCGCGTCTGTGGCGCAGGCTCGCGGCTACGACGTTGACAAACCGCGAAATCTGGCCAAGTCCGTCACCGTTGAGTAAC

Protein Sequence 

>ML0371_GlmS_protein
CVDLSATSGSALPAGSSWMRCAGWSTAATTRRESR_STAVPNRAI_PFVVVLVDFPIWSRCWRRWFRRRWPATSASAISGGPPMVAPPTATRIRTATPPARSPSSTTASSRISPPFAMSWRSPE_SSSATPTPR_LCIWWHRLTALARRPVISSGPCWRCCAGYRATSLWCSPTPTSPVPLWPRAAPPR_CSGSATGRCSSVPTWPRSSNTPGRRSSLVRTRLW_SLQMVTESATSMATMTL_TLAHFISTGTWPLPKRAATSTSCSRKSLSSPTR_STRYLGISLVDGLCSTNSD_AIRNSARSIRCLWSLAVLPIIPACWPNIRSSTGRGCLLRWS_PANFATGILFWTAAHWW_PFRSPVKPLIL_KLSGTLKSRRPRCWRFATPTAPKSHVSATRCCILALARRSASPQRKPFWLRSPPTTSLGWRWRRPAALSTPMRCSASTASWKRCPTWWPGSSRGWAPWPIWLTGSLSRRPCCSWVAMSGTRWRWKVR_NSRNWPTCTPRGSPPASSSTDPSR_SKKTCR_SSSCPRPRDRRCCMLSC_ATFVKFRPAER_PL_SRRKATTRYVSTPIT_SNSPRCQHFCSRCCRPSRCRCSPRLWRRLAATTLTNREIWPSPSPLSN

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GlmS with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

26 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GlmS

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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