gcp
mL0379
Probable O-sialoglycoprotein endopeptidase Gcp (Glycoprotease)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 471841 – 472896
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0379_gcp_dna
TGACGATCTCTGCTGTGCCCGGCACGATTATCTTGGCCATCGAAACCTCTTGCGATGAAACCGGTGTTGGTATTGCCTGCCTCGATGACTATGGCACCGTGACATTGTTGGCTGACGAGGTGGCTTCCAGCGTCGACGAGCAGGCCCGGTTTGGTGGTGTGGTGCCCGAGATTGCCTCACGGGCGCATCTAGAGGCTCTTGGCCCCACCATACGCTGCGCGCTTGCTGCTGCCGGCCTGACCGGTTCGGCCAAGCCAGATGTTGTAGCCGCCACGATAGGGCCCGGGTTAGCCGGTGCTTTGTTGGTAGGAGTGGCTGCGGCTAAAGCGTACTCGGCTGCCTGGGGAGTGCCGTTCTACGCCGTGAACCACCTGGGTGGACACCTGGCTGCCGACGTCTACGAACATGGACCGTTGCCCGAGTGTGTGGCGCTACTGGTGTCTGGAGGCCATACCCACCTGTTGCAGGTGCGTTCACTTGGGGCGCCCATTGTCGAGCTGGGCAGTACCGTCGACGACGCCGCCGGTGAAGCTTACGATAAGGTCGCGCGCCTACTGGGATTGGGTTATCCAGGCGGTAAAGTGCTAGACGACCTAGCTCGTACCGGCGATCGGGATGCCATTGTGTTCCCACGCGGCATGACTGGGCCGGCCGACGACCTAAACGCGTTCAGCTTTTCAGGGCTCAAAACCGCTGTCGCACGATATGTCGAGAGTCACCCCGACGCGCTGCCGGCCGATGTCGCCGCTGGGTTTCAGGAGGCTGTCGCCGATGTGTTGACCATGAAGGCGGTGCGTGCGGCGACCGGGCTCGGCGTTTCCACTTTGTTGATCGTCGGGGGAGTGGCCGCGAATTCGCGGCTGCGCGAGCTAGCCGCGCAGCGCTGCGCGGCGGCGGGGCTGATGCTGCGGATCCCAGGGCCGCGGTTCTGCACCGACAACGGGGCGATGATCGCCGCGTTCGCCGCACATCTGCTGGCTGCGGCCGCGCCACCGTCACCGTTGGATGTGCCCAGCGACCCGGGCCTTCCGGTGGTAAAAAGGCAGATTAATTGAG

Protein Sequence 

>ML0379_Gcp_protein
RSLLCPARLSWPSKPLAMKPVLVLPASMTMAP_HCWLTRWLPASTSRPGLVVWCPRLPHGRI_RLLAPPYAARLLLPA_PVRPSQML_PPR_GPG_PVLCW_EWLRLKRTRLPGECRSTP_TTWVDTWLPTSTNMDRCPSVWRYWCLEAIPTCCRCVHLGRPLSSWAVPSTTPPVKLTIRSRAYWDWVIQAVKC_TT_LVPAIGMPLCSHAA_LGRPTT_TRSAFQGSKPLSHDMSRVTPTRCRPMSPLGFRRLSPMC_P_RRCVRRPGSAFPLC_SSGEWPRIRGCAS_PRSAARRRG_CCGSQGRGSAPTTGR_SPRSPHICWLRPRHRHRWMCPATRAFRW_KGRLIE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Gcp with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

10 show intermediate predicted evidence for PPIs

76 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Gcp

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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