guaB3
mL0388
Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogenase) (IMP oxidoreductase) (IMPD) (IMPDH)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 482275 – 483387
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0388_guaB3_dna
TGGGCCGCGTGGCCCGTCGAACATATGAGCTCCGTGAGATCAGCATCGTGCCGTCGCGTCGCACTCGCTCGTCGAAAGACGTGTCGACGGCTTGGCAACTCGACGCCTACCGGTTCGAGATCCCCGTCGTGGCACACCCGACCGATGCGTTAGTGTCGCCGGAGTTCGCCATCGAGCTGGGCCGGCTTGGTGGGCTGGGTGTGCTCAACGGTGAGGGGCTGATTGGCCGCCATGCTGATGTCGGTGCCAAGGTCGCACAGTTGATCGAGGCTGCCGAGAAAGAGCCTGAACCGGCGACTGCGGTCTGTTTGCTGCAGGAACTGCATGCTGCGCCGCTGAATCCGGACCTGCTGGGTTCGGCGGTAGCTCGGATTCGGGAGGCGGGAGTGACCACTGCAGTGCGAGTCAGCCCGCAAAATGCCCAAGTGTTGACGCCGGTGTTGCTCGCTGCCGGAATTGACCTACTGGTCGTCCAGGGTTCCATCGTCTCGGCCGAGTGTGTTGCCAGCGGTGGTGAACCACTCAACCTGAAAACATTCATCTCTGAGCTCGACGTTCCGGTGGTCGCTGGCGGTGTGCTCGACCACCGCACGGCGCTGCACCTGATGCGCACCGGCGCGGCTGGCGTGATCGTCGGCTATGGCTCCACTAGAGGGGCCACTACCTCCGATGAAGTGTTAGGCATCAGCGTGCCGATGGCTACGGCGATCGCCGACGCGGCTGCTGCGCGGCGCGAATACCTCGATGAGACCGGTGGTCGCTACGTCCACGTGCTGGCCGACGGCGATATCTACACGTCTGGCGAGTTGGCCAAAGCTATTGCCTGTGGTGCCGACGCGGTGGTGCTGGGTACACCGTTGGCCCAAAGTGCCGAGGCACTCGGCGGCGGGTGGTTCTGGCCGGCCGCGGCGGCGCACCCGTCTCTGCCACGCGGGGCGTTGCTACAGACCGCTGTCGGTGAGCGACCGTCATTGCAGCAGGTTTTGAACGGGCCCTCCGACAACCCATTCGGCACCCTGAATCTTGTTGGTGGTCTGCGCCGATCTATGGCTAAGGCCGGCTATTGCGACCTCAAGGAATTCCAGAAGGTCGGTCTGATCGTCAGCATCTGAG

Protein Sequence 

>ML0388_GuaB3_protein
WAAWPVEHMSSVRSASCRRVALARRKTCRRLGNSTPTGSRSPSWHTRPMR_CRRSSPSSWAGLVGWVCSTVRG_LAAMLMSVPRSHS_SRLPRKSLNRRLRSVCCRNCMLRR_IRTCWVRR_LGFGRRE_PLQCESARKMPKC_RRCCSLPELTYWSSRVPSSRPSVLPAVVNHST_KHSSLSSTFRWSLAVCSTTARRCT_CAPARLA_SSAMAPLEGPLPPMKC_ASACRWLRRSPTRLLRGANTSMRPVVATSTCWPTAISTRLASWPKLLPVVPTRWCWVHRWPKVPRHSAAGGSGRPRRRTRLCHAGRCYRPLSVSDRHCSRF_TGPPTTHSAP_ILLVVCADLWLRPAIATSRNSRRSV_SSASE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GuaB3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

6 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GuaB3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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