espD
mL0407
ESX-1 SECRETION-ASSOCIATED PROTEIN ESPD
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 504794 – 505444
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0407_espD_dna
TGGGAAGTAGACGTCGGATTAACCGACGTCTACTTCCCATGTCGACTTTTCCTGCGTGGCAGGAATTCAGGAGGGATGTCGTGGTGGTGTTCCCCGGAAACGACTTCGACCGCGATGATTGCGACACCGTGGATCCCTGGGGCGTCGGCGGTGCGGCGCACTGGACTATAGATCCGATTGTTGGCTTTGCGTCGTCGTCGGCGCCCCAGGACCGCGGAACCGACGTAGACAACACCCGCGGTCAGGCTGAGGAGGATGAAAAACAAAAGGAGCCAGAGGTCGCAATTTTCACGGTGACGAACCCCCCACGTACCGTGTCGGTATCGGTGCTGATGGACGGCCGGATCGACCATGTTGAGCTTTCGAAGAGGGTGACATGGATGAGTGAATCACAGGTCGCCTCCGAGATCCTGGTTCTTGCTGACTTGGCGCGGCAGAAGGCGCAGTCGGCCCAGTACACTTTCATCCTAGACAAACTGAGTCAACTGGCCGATGGAGATGAGCACCGCGTCGCACTGTTACGTGAATCCGTGGGCAATACCTGGAATTTGCCGTCGCCGGAACAAGCCGCAGAGGCAGAAGCTGAAGTATTCGCAACTCGTTACAGTGACTATTGTCCTGCACAAGATACAGAGAATGATCAATGGTGAA

Protein Sequence 

>ML0407_EspD_protein
WEVDVGLTDVYFPCRLFLRGRNSGGMSWWCSPETTSTAMIATPWIPGASAVRRTGL_IRLLALRRRRRPRTAEPT_TTPAVRLRRMKNKRSQRSQFSR_RTPHVPCRYRC_WTAGSTMLSFRRG_HG_VNHRSPPRSWFLLTWRGRRRSRPSTLSS_TN_VNWPMEMSTASHCYVNPWAIPGICRRRNKPQRQKLKYSQLVTVTIVLHKIQRMINGE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EspD with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

27 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EspD

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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