otsB2
mL0414c
Possible trehalose-6-phosphate phosphatase OtsB2 (Trehalose-phosphatase) (TPP)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 511985 – 513274
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0414c_otsB2_dna
AATGCCGGTCACCATAGACCCGCGGCGCCACAGCGCAGCACTGTTCGACCTCGACGCCGTAGTGACCGACACCCCACTCGACTCCACAGTGACGCTGGTCCGGCAACTTCAGGGGATCGGTGTGGGTACCGCCGTTTTTTCGACCAACCGCAACAGCCAGGGCGTGCTGACTGCAACCGGCCTCGACCATCTGTTCCCCGTCCACGTTGACGGCCTAGCTAGCGGAAAAGTCACCATCCTAGTCGCCGCGGCCAACCGCTTAATGGCGCAACCAGGCCGGTGCGTCGTCGTCGCAGTCGACGCGGCCGGCATAACGGCCGCACGCTATGGCGGTTTCGCGCTGGTGCTCGGCCTAGTAATAGGGGAAGATCAGACAGGCCACCGCGACACACTGCGTAACTCCGGCGCCGACACGGTAGTTGCCGACCTAGGTGAGGTCATCGTCCGAACCGGGGACCGCCGGATGTCGGAACTTCCCGACGCGCTGCAGACCCTCGGCTTAACTGACGACCTCACCGCTCGGCAGCCGGCGGTGTTCTTCGACTTCGACGGCACACTGTCAGACATCGTCGATGATCCCGACTCGGCCAGACCCGTTCCCGGCGCGACCGAAGCATTGCAGAAGTTGGCCACACATTGTCCAGTGGCCATACTGTCTGGTCGCGATCTCGCAGATGTAATCAAGCGCATCGGCGTGCCCGGAATCTGGTATTCCGGCAGTCATGGTTTTGAGTCAACTGCACCCGACGGCACACATCATCAAAACGACGCAGCGGAAGCGACGATACCCATACTGGAGCAAGCGGCGACCCAGCTACGCGACCAACTCGGACCAATTCCGGGAGTCATGGTGGAACACAAGCGTTTTGGCGTAGCAGTGCACTACCGTAACGTCGCGCGTGACCGCGTCAACGAGGTCGCAGTGGCGGTGCGCACAGCAGGCCAGCGCAACGCACTTCGGGTGACAACAGGTCGCGAGGTCATCGAGCTGCGTCCCGACATCGACTGGGACAAGGGAAAAACACTCCATTGGGTGATCGATCGCCTGCACCATGCCGGCACTCAAGTAGGCTCAGCTTCGCTCATGCCGATCTGTCTCGGCGACGACATAACCGACGAGGACGCGTTCGACGCAGTGCGCCACACCGACGTTGGGGGTATTCCGATCGTGGTACGACACACTGAAGACGGTAACCGCGCAACAGCCGCATTGTTCACGTTGGACAGTCCTATGCACGTCAGTGAATTCACCGAACGGTTGGCACGCCAGCTTAGTGACACTCAACGCTA

Protein Sequence 

>ML0414c_OtsB2_protein
NAGHHRPAAPQRSTVRPRRRSDRHPTRLHSDAGPATSGDRCGYRRFFDQPQQPGRADCNRPRPSVPRPR_RPS_RKSHHPSRRGQPLNGATRPVRRRRSRRGRHNGRTLWRFRAGARPSNRGRSDRPPRHTA_LRRRHGSCRPR_GHRPNRGPPDVGTSRRAADPRLN_RPHRSAAGGVLRLRRHTVRHRR_SRLGQTRSRRDRSIAEVGHTLSSGHTVWSRSRRCNQAHRRARNLVFRQSWF_VNCTRRHTSSKRRSGSDDTHTGASGDPATRPTRTNSGSHGGTQAFWRSSALP_RRA_PRQRGRSGGAHSRPAQRTSGDNRSRGHRAASRHRLGQGKNTPLGDRSPAPCRHSSRLSFAHADLSRRRHNRRGRVRRSAPHRRWGYSDRGTTH_RR_PRNSRIVHVGQSYARQ_IHRTVGTPA__HSTL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding OtsB2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

21 show weak predicted evidence for PPIs

View all pooled AlphaFold results for OtsB2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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