ML0430
mL0430
Probable conserved integral membrane leucine and alanine rich protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 529521 – 530885
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0430_ML0430_dna
TGAATCAGCCAGAGTCGGTCGCGGGTACCATGGTGCGATCTTGGGTTGTGGCGTGGGCGATGTGGGACTGCGGTTCGACTGGTCTTACCGCCATCGTGGCAACCTTCGTCTTCTCCGTCTACCTGACCAGCAGTGTTGGTGTAGGTATGCCTGACGGTATCTCACTGGTGAGTTGGCTGGGTCGCGCGGGGGCCGTTGCCGGGTTAACCATTGCGGTGCTGGCGCCGGCCATCGGTGTATGGGTGGAGTCACCACATCGCCGTCGGGTGACGCTGGGTGTGCTGACTGTCCTCGCGGTAGCGTTGACCTGCGGGATGAGCTTTATCCGCGATCAACCTAGTTACCTTTGGGCTGGATTGATGCTGCTGGCCGGAACAGCTGCATGCGGTGACCTGGCCAGCGTTCCTTACAATGCAATGCTACGTCAGCTATCGACGCCGGCGACAGCCGGCCGGATTTCCGGCTTGGGTTGGGCGTCGGGATATGTTGGTAGCGTCGTTTTGTTGCTACTGATCTACCTGGGTTTTATTTCCGGAACCGGTGAGCTGCGCGGGCTGCTCCAGCTGCCCACCCATGACGGAATCTACGTACGCGCGGCGATGTTGCTGGCTGCGGCATGGTTGGCTTTGTTGGCTCTGCCGCTGCTGCTAACGGCACACCGACTGCCCTCGTTGGGCGAGGTGTCTCATCCGACGAGCATGCTGGGTGGCTACCGCAAGCTGTGGTCGGAGGTCTCCGCGGAATGGCGACGCGACCGCAACCTGGTCTACTTCCTGGTGGCCAGTGCACTTTTCCGGGACGGTTTGGCGGCGACTTTAGGTTTCGGCGCTGTGCTCGGTGTTAACGCCTACGGGATTTCACAAGCCAATGTGTTGATGTTCGGTGTGGTGGCAAGCTTGGTGGCTGCAGTGGGGGCGGTTCTCGGCGGGTTTGTCGACCACCGGATCGGATCCAAACGAGTCATCGTGGGATCACTGGTTGCTATCATCGTCACGGCTCTGACCTTGATGACGCTCTCCGGCCCGCTCGCCTTCTGGGTGTGCGGATTGGTGCTGTGTCTGTTCATCGGACCTTCGCAGTCGTCGTCGCGCGCTCTGTTATTGCACATGGCGAAGCACGGCAGGGAAGGCGTGGCGTTCGGCCTTTACACGATGACGGGACGGGCGGCGTCGTTCGTGGCACCGTGGTCTTTCTCTATATTTGTCGACGGCTTCGGCGTCGTCCGGGCCGGTCTGGGAGGTATCTCAGTAGTGCTGCTGGCAGGGCTGCTGGGAATGCTGATGGTTCGCGTTCCAACGCGGCGCGAAGCGGCCGCGGTCGGGTTGTCTTGGTGGCGATCGCAAGCACGGCGGGGCCAGGTGTAGT

Protein Sequence 

>ML0430_ML0430_protein
ISQSRSRVPWCDLGLWRGRCGTAVRLVLPPSWQPSSSPST_PAVLV_VCLTVSHW_VGWVARGPLPG_PLRCWRRPSVYGWSHHIAVG_RWVC_LSSR_R_PAG_ALSAINLVTFGLD_CCWPEQLHAVTWPAFLTMQCYVSYRRRRQPAGFPAWVGRRDMLVASFCCY_STWVLFPEPVSCAGCSSCPPMTESTYARRCCWLRHGWLCWLCRCC_RHTDCPRWARCLIRRACWVATASCGRRSPRNGDATATWSTSWWPVHFSGTVWRRL_VSALCSVLTPTGFHKPMC_CSVWWQAWWLQWGRFSAGLSTTGSDPNESSWDHWLLSSSRL_P__RSPARSPSGCADWCCVCSSDLRSRRRALCYCTWRSTAGKAWRSAFTR_RDGRRRSWHRGLSLYLSTASASSGPVWEVSQ_CCWQGCWEC_WFAFQRGAKRPRSGCLGGDRKHGGARCS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML0430 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

36 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML0430

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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