pgsA
mL0454c
Probable PI synthase PgsA1 (phosphatidylinositol synthase) (CDP-diacylglyceride--inositol3-phosphatidyltransferase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 554334 – 555053
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0454c_pgsA_dna
TATGAGCAAGGTGCCATTCCTGTCCCGGGCGACGTTTACGCGGCTCACGACTCCGACCGCAAGAGCGTTGCTGCGGGTCGGCTTGACGCCGGATGCCATCACCGTCTTAGGCACCATCGTGGCTGCGTCGGGGGCGCTGGTACTTTTCCCGATCGGCAAACTCTTCGCCGGTACTCTGGTAGTCTGGTTTTTCGTACTTTTCGACATGCTCGACGGGGCGATGGCCAGGGAACGTGGCGGCGGCACCCGGTACGGCGCGGTTCTCGATGCGACGTGTGACCGTATCAGTGACGGAGCGGTATTCTGCGGACTGCTGTGGTGGATGGCGTTCGGCCTGCACAGCAAACACCTGGTGGTGGCAACCTTGATCTGTTTGGTCACCTCGCAGGTGATTTCTTACATCAAGGCCCGGGCCGAAGCCAGCGGGCTACGCGGCGATGATGGCCTCATCGAACGGCCGGAACGTTTGATCATCGTGCTGGTCGGTGCGGGCTTATCGGACTTTCCGGTGTATTCGTTGCCGTGGGCGTTGTCGGTGGCGATGTGGCTGTTAGTGGTCGCCAGCCTCATCACCTGTGCGCAACGGTTGCACACAGTGCACACCTCGCCGGGGGCAACCGATCGCATTGCCAGACCAGGCTACCCTAGCGCTAGCGACAGGACTAACGCGACGAATGGGGGCCAACCCGGTCCCGGAAACCTGGGAACAGGCGAGCCGTG

Protein Sequence 

>ML0454c_PgsA_protein
YEQGAIPVPGDVYAAHDSDRKSVAAGRLDAGCHHRLRHHRGCVGGAGTFPDRQTLRRYSGSLVFRTFRHARRGDGQGTWRRHPVRRGSRCDV_PYQ_RSGILRTAVVDGVRPAQQTPGGGNLDLFGHLAGDFLHQGPGRSQRATRR_WPHRTAGTFDHRAGRCGLIGLSGVFVAVGVVGGDVAVSGRQPHHLCATVAHSAHLAGGNRSHCQTRLP_R_RQD_RDEWGPTRSRKPGNRRAV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PgsA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

15 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PgsA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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