thrS
mL0456c
Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 555663 – 557771
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0456c_thrS_dna
GATGAGCGCCCCCGTACACCCCGTCCCTGGAGCCGATGGCGGCGACCCGCTGCGCCCGGCCACGCCGGGCTTGCGGTCGCCGCAAGTCCCAATCCAGGTTCCTGCCGGTAGTACCGCAGCGGCCGCGGTCAGCGAGGCCGGATTGCCAACACATGGCGCTCCCGATGCGATTGTGGTGGTGCGCGACGCCGACGGGAAGTTACGCGACTTAAGCTGGGTTCCGGACGTCGACGTCGAGGTGACTCCGGTACCCGTCAATACCGACGACGGCCGCAGCGTGATCCGGCATTCGACGGCACACGTTTTGGCCCAAGCTGTCCAAGACCTGTTCCCACAAGCCAAACTGGGGATCGGGCCGCCTATTACCGATGGCTTCTACTACGACTTCGACGTGGCCGAACCGTTCACGCCTGAAGATTTAAAGGCGCTAGAAAAGCGGATGCGGCAGATTGTCAAGGAAGGGCAGCTGTTCTCGCGACGGATCTACGAATCCAAGGAGCAAGCTCGTACCGAGTGGGCCGGCGAACCATACAAGCTGGAACTTGTCGACGACGAATCGGGGGATGCCGAGATCATGGAGGTCGGCGGCGATGAGCTCACCGCTTATGACAACCTCAACGCCCGCAACGGGGAACGTATTTGGGGTGACCTGTGCCGCGGACCACACATCCCAACTACCAAGCACATTCCTGCGTTCAAGCTGACCAGAAGTTCCGCTGCGTACTGGCGAGGCAACCAGAAAAACGCCAGCCTGCAGCGCATCTATGGTACCGCGTGGGAATCGCAGGAGGCCCTCGATCGCCACCTTGAGATGATTACCGAGGCCCAGCGCCGCGACCATCGCAAGCTGGGCATTGAGCTGGATCTGTTCAGTTTCCCCGACGAAATCGGTTCTGGCTTAGCGATTTTTCACCCTAAGGGGAGCATCGTACGTCGGGAAATGGAAGAGTACTCCCGGCGCAAGCACATCGAAGCCGGCTACCAATTCGTCAACACCCCGCATATTACCAAGGCGCAGCTGTTCCACACTTCGGGTCACCTCGACTGGTACGCCGAGGGTATATTCCCCCCGATGCACCTCGACGCCGAACACAACGATGACGGCACGGTGCGTAAGCCAGGGCAAGACTACTACCTCAAGCCAATGAACTGCCCGATGCACACCCTGATTTTCTCCTCGCGCGGACGTTCGTATCGAGAGTTGCCACTACGGCTCTTCGAGTTCGGCACGATCTACCGCTACGAGAAATCTGGTGTAGTACATGGGCTTACCCGTGCCCGCGGGTTCACCATGGACGACTCGCACATCTTCTGCACCCGCGAGCAGCTGCACTGCGAGCTGGCGTCGCTGCTCCGGTTCGTCCTGGATCTTCTTGGCGACTATGGGCTAGAAGATTTTTACCTCGAGCTTTCTACTAAAGACCCGGAGAAATTTGTTGGCTCCGAAGAGATCTGGGAAGAAGCCACAGCCGCGCTGGCGGAGGTAGCCGAGAATTCTACTCTCCCATTGGTTCCCGATCCAGGTGGCGCCGCGTTCTACGGCCCGAAGATCTCGGTGCAGGTGCGCGACGCACTGGGTCGCAGCTGGCAGATGTCCACCATCCAGGTAGACTTCAACTTTCCCGAACGGTTCGCATTGGAGTACACCTCCGCGGACGGGACTCGGCAGCGCCCAGTCATGATTCACCGGGCGTTATTCGGATCAATCGAGCGATTCTTCGGCATCCTCACCGAACACTATGCGGGAGCATTCCCTGCCTGGCTAGCGCCCATTCAGGTGGTCGGTATACCGGTCACCGGTGAGCATGTATCTTACTTGGAAGAGGTTGCTGCGCAACTGAAATCGTGTGGTGTCCGGACGGAGGTGGATGTCAGCGACGATCGGATGGCAAAGAAAATCGTCCGTCACACCAACCAGAAAGTGCCGTTTATGTTACTGGCCGGCGACCGCGACGTGCGGACCGGGTCGGTGAGCTTCCGCTTTGGTGACCGCACACAGATCAACGGCGTCGCCCGCGACAGTGCCGTCGAGGCCATCGTTTGTTGGATCGTTGACCGCGAGAATGATTTTCCCACAGCAGAATTGGTGAAAGTAACCGGCGGTGAGTG

Protein Sequence 

>ML0456c_ThrS_protein
DERPRTPRPWSRWRRPAAPGHAGLAVAASPNPGSCR_YRSGRGQRGRIANTWRSRCDCGGARRRREVTRLKLGSGRRRRGDSGTRQYRRRPQRDPAFDGTRFGPSCPRPVPTSQTGDRAAYYRWLLLRLRRGRTVHA_RFKGARKADAADCQGRAAVLATDLRIQGASSYRVGRRTIQAGTCRRRIGGCRDHGGRRR_AHRL_QPQRPQRGTYLG_PVPRTTHPNYQAHSCVQADQKFRCVLARQPEKRQPAAHLWYRVGIAGGPRSPP_DDYRGPAPRPSQAGH_AGSVQFPRRNRFWLSDFSP_GEHRTSGNGRVLPAQAHRSRLPIRQHPAYYQGAAVPHFGSPRLVRRGYIPPDAPRRRTQR_RHGA_ARARLLPQANELPDAHPDFLLARTFVSRVATTALRVRHDLPLREIWCSTWAYPCPRVHHGRLAHLLHPRAAALRAGVAAPVRPGSSWRLWARRFLPRAFY_RPGEICWLRRDLGRSHSRAGGGSREFYSPIGSRSRWRRVLRPEDLGAGARRTGSQLADVHHPGRLQLSRTVRIGVHLRGRDSAAPSHDSPGVIRINRAILRHPHRTLCGSIPCLASAHSGGRYTGHR_ACILLGRGCCATEIVWCPDGGGCQRRSDGKENRPSHQPESAVYVTGRRPRRADRVGELPLW_PHTDQRRRPRQCRRGHRLLDR_PRE_FSHSRIGESNRR_V

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ThrS with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

25 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ThrS

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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