ruvC
mL0481
Probable crossover junction endodeoxyribonuclease RuvC (HOLLIDAY JUNCTION NUCLEASE) (HOLLIDAY JUNCTION RESOLVASE).
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 581225 – 581791
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0481_ruvC_dna
TGCGCGTGATGGGCGTCGATCCCGGGTTGACGCGGTGCGGGTTGTCTGTCGTCGAAAATGGGCGCGGTAGCCAAGTTGTTGCGTTGGATGTCGATGTGGTGCGCACACCATCGGACGCACCGGTATCCAAGCGCTTGCTGGCTGTCAGCGATGTCGTCGAACACTGGCTGGACGCCCATCATCCGGATGTTATGGCCATCGAACGGGTTTTTTCTCAGCAGAATGTGTCGACGGTGATGGGTACGGCACAAGCCGGCGGTGTGATCGCGTTGGCCGCGGCGAGACGCGGTATCGACGTACATTTCCATACCCCAAGTGAGGTTAAGGCCGCAGTTACCGGCAATGGTGCCGCCAACAAAGCGCAAGTTACCGCGATGGTGACCAGAATCCTTGCACTGCAAGCTAAACCGACACCGGCCGATGCGGCCGACGCGTTGGCCCTGGCGATCTGCCACTGCTGGAGAGCACCAATGATCGCGCGGATGGCAGAAGCCGAAGCGCTGGGCGCGCGGCACCGTCAGGCCTATCGGGCCAAGGTAGCTGGCGAGGTTAAGGCCACCCGGTGAT

Protein Sequence 

>ML0481_RuvC_protein
CA_WASIPG_RGAGCLSSKMGAVAKLLRWMSMWCAHHRTHRYPSACWLSAMSSNTGWTPIIRMLWPSNGFFLSRMCRR_WVRHKPAV_SRWPRRDAVSTYISIPQVRLRPQLPAMVPPTKRKLPRW_PESLHCKLNRHRPMRPTRWPWRSATAGEHQ_SRGWQKPKRWARGTVRPIGPR_LARLRPPGD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding RuvC with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

30 show weak predicted evidence for PPIs

View all pooled AlphaFold results for RuvC

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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