ruvA
mL0482
Probable Holliday junction DNA helicase component RuvA
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 581788 – 582399
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0482_ruvA_dna
TGATTTTCTCGGTACGCGGCGAGGTACTCGAGGTGGCACTTGACCACGCCGTCATCGAAGCCGCCGGTATCGGCTATCGGGTAAACGCGACGCCGTCGGCGTTGGCGACGTTGCGGCAGGGCAGCCAGGCCCGACTGGTCACCGCAATGGTCGTGCGCGAGGACTCGATGACGTTGTACGGGTTTTCTGATGCCGAGAACCGTGACCTATTCCTAGCGCTGCTGTCAGTCTCGGGAGTTGGGCCTCGCCTTGCCATGGCGACATTGGCCGTGCACGACGCTGCGGCGCTTCGGCAGGCACTGGCCGATAGTGATGTCGCCTCGCTGACCCGGGTGCCCGGTATCGGCAAGCGTGGTGCCGAACGGATAGTGCTGGAGTTACGCGACAAGGTTGGCCCGGTAGGGGCGTCTGGATTGACTGTGGGTACTGCTGCTGACGGCAACGCGGTGCGAGGTTCTGTGGTCGAAGCCCTGGTAGGGCTGGGTTTTGCGGCCAAGCAGGCCGAGGAAGCGACCGACCAGGTGCTCGACGGTGAACTTGGAAAAGATGGGGCGGTGGCAACGTCCAGCGCCTTGCGGGCTGCTCTGTCGTTGCTGGGCAAGACCCGATGAG

Protein Sequence 

>ML0482_RuvA_protein
FSRYAARYSRWHLTTPSSKPPVSAIG_TRRRRRWRRCGRAARPDWSPQWSCARTR_RCTGFLMPRTVTYS_RCCQSRELGLALPWRHWPCTTLRRFGRHWPIVMSPR_PGCPVSASVVPNG_CWSYATRLAR_GRLD_LWVLLLTATRCEVLWSKPW_GWVLRPSRPRKRPTRCSTVNLEKMGRWQRPAPCGLLCRCWARPDE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding RuvA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

18 show weak predicted evidence for PPIs

View all pooled AlphaFold results for RuvA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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