secD
mL0487
Probable protein-export membrane protein SecD
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 590037 – 591830
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0487_secD_dna
TGTCTTGTGTGAAGGGCCTAGTGATGCGACACGTAGGCTCTGTCGGGAAAAACCGATTTCGAGGAGATACAAGGAACGTGGCATCGTCTTCGGCGCCAGTGCATTTTGGCCGCTACCTGTCGATGTTTCTGGTGTTATTCATCGGGGTCTATCTGTTAGCGTTTCTCACCGGAGACAAGCGGGTCGTTCCCAGGCTCGGCATAGACCTCCAAGGCGGCACCCGCGTAACGTTGACCGCGCGCACGCCCGACGGCTCGCGCCCCAGCCGGGAGGCGTTGTCACAGGCGCAGCAGATCATCAGCTCCCGGGTTAACGGGCTCGGAGTATCGGGTTCGGAAGTGGTCGTCGATGGCGACAACCTGGTCATCACTGTGCCCGGCAACGACGGCAACGAGGCCCGCAACCTGGGCCAGACTGCGCGTCTGTACATCCGGCCGGTGCTTAACTCGCTACCCGTGCAACGTGGTCAAGACCCCAAGCCGGGTTCCCCTGCCGGCACGTTGCCCAATTTCGCGCCGATGCCGCCCGACCACCCAGGCGCGCAACCACGCCCCTACCTGCAAGATCCGACGTCATCACCTAGCTCAGATCCGATGCCAAGTCCAGTGCCAACCGGAGCGGCACTACCGGGTGAGGTTCCCTCGGTTGAGCAGCCCGCGCCACCGGATCCGCGTAAGGATCTAGCTGAACGCATTGCCGAGGAGAAGAAGTGGCGGCAAAGCACCAAACAGAGTATTCAGTTCCTCGCATTGCAGTTCGAATCCACCCACTGCGACAAAGACGACATTCTGGCCGGCAATGACGACCCGAATCTGCCTCTGGCGACCTGCTCGACCGACCATAATATGGCGTATTTGTTAGCGCCATCGATCATCAGCGGCGACCAGATCCAAAACTCCACGTCCGGCATGAACCAGCGTGGGGTCGGCTACGTCGTCGATCTGCAGTTCAAGTCTGCGGCCGCAGATGTCTGGGCTGACTTCACCGCCGCCCACATCGGTACTCAGACCGCTTTCACCCTGGACTCCGAGGTGGTCAGCGTCCCGGTAATCAACGAGGCAATTTTGGGCGGGCGTACCCAGATCAGTGGTGGAGATCCGCCGTTCACCGCCGCAACCGCGCGCCAGCTGGCCAACGTTTTGAAATACGGATCGCTGCCGCTATCTTTCGAGCCGTCGGAAGCTCAAACAGTTTCGGCGACTTTGGGGTTGACATCGTTACGGGCGGGTCTGATCGCAGGTGCGATCGGCCTGAGCCTAGTGTTGCTGTACTCGTTGCTATATTACCGGGTACTTGGATTGCTCACCGCGTTTTCGCTTTTCTGTTCCGGCACAATAATTTTTGCGATCTTGGTGCTCTTGGGTCGATATATCAATTATACTTTGGACCTTGCGGGTATCGCGGGTCTGATCATCGGTATCGGCACCACTGCCGACTCCTTCGTGGTGTTTTTCGAGCGGATCAAAGATGAGATCCGCGAAGGCCGTTCGTTCCGGTCGGCTGTTCCTCGTGGCTGGGTGCGTGCCCGCAAGACGATCGTGTCCGGCAACGCTGTCACCTTCCTGGCGGCTGCTGTGCTGCACTTCCTGGCGATTGGCCAAGTAAAGGGATTTGCTTTCACCCTCGGCCTTACCACGATCCTGGACCTGGTGGTGGTGTTCCTGGTGACCTGGCCGCTGGTGTACTTGGCTTCCAAGTCTCCGTTGCTGGCAAGGCCGGCATACAACGGCTTGGGCGCCGTTCAACAGGTTGCCCGCGAACGACGGGCTTCCGCCAAGACAGGACGGGGGTAGC

Protein Sequence 

>ML0487_SecD_protein
CLV_RA__CDT_ALSGKTDFEEIQGTWHRLRRQCILAATCRCFWCYSSGSIC_RFSPETSGSFPGSA_TSKAAPA_R_PRARPTARAPAGRRCHRRSRSSAPGLTGSEYRVRKWSSMATTWSSLCPATTATRPATWARLRVCTSGRCLTRYPCNVVKTPSRVPLPARCPISRRCRPTTQARNHAPTCKIRRHHLAQIRCQVQCQPERHYRVRFPRLSSPRHRIRVRI_LNALPRRRSGGKAPNRVFSSSHCSSNPPTATKTTFWPAMTTRICLWRPARPTIIWRIC_RHRSSAATRSKTPRPA_TSVGSATSSICSSSLRPQMSGLTSPPPTSVLRPLSPWTPRWSASR_STRQFWAGVPRSVVEIRRSPPQPRASWPTF_NTDRCRYLSSRRKLKQFRRLWG_HRYGRV_SQVRSA_A_CCCTRCYITGYLDCSPRFRFSVPAQ_FLRSWCSWVDISIILWTLRVSRV_SSVSAPLPTPSWCFSSGSKMRSAKAVRSGRLFLVAGCVPARRSCPATLSPSWRLLCCTSWRLAK_RDLLSPSALPRSWTWWWCSW_PGRWCTWLPSLRCWQGRHTTAWAPFNRLPANDGLPPRQDGGS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding SecD with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

44 show weak predicted evidence for PPIs

View all pooled AlphaFold results for SecD

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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