secF
mL0488
Probable protein-export membrane protein SecF
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 591835 – 593250
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0488_secF_dna
TGGTCTCCAGAGCCAAAGTCGGCGCCGAGACCACCAAGGGTATCGACGAACCAGACCGAAATGACAACACCGACGACAATGGCGCCGGTGCGGTCGAAGTCACCGAAGCCGCCGAGGATGCCGTGGAGCTGACTAACGATATATCCACACAGCTGCCGCAGCACGGCTTTCTTGCTCGGTTCTACACCGGCCTTTCTCGACTGTACACCGGCACCGGTGTGTTCGAGGTGGTGGGACGCCGGCGGCTGTGGTACAGCGTGGGCGGCGTCATCGTGGCGGTTGCGGTCCTGTCCATTATCGTTCGCGGGTTTACTTTCGGGATTGATTTCAAGGGCGGCACCACGGTGTCCATGCCTGTCTCGCCCGGAGTGGGGGGGACAGGCGCAATTGAGGTTGCGCAGGTTGCCGATGTCTTCAAGAAGACCCTTGGCAGTGATCCGGAATCGGTGGTCGTTGTTGGTAACGGCGCGTCAGCAACGGTGCGGATCAGTTCGAAAACGCTGTCCAATGACCAGACGTCGAAGCTGCGTAACGCCTTGTTTGACGCATTCGGACCCAAAGGCGCCGACGCTAAGCCTAGCAAGCAGGCAATCAGCGACGCGGCGGTATCGGAGACCTGGGGCGGTCAGATCACCAAGAAGGTGGTGATCGCTCTTGTGGTGTTTCTGGTGCTAGTCGGCCTGTACATCACTGTGCGGTACGAGCGTTATATGGCTATCTCCGCACTGACTACCATGTGTTTTGACCTGACCGTCACAGCCGGCGTGTACTCGCTGGTGGGCTTCGAAGTCACTCCGGCCACTGTCATCGGCTTGTTGACGATCCTCGGTTTCTCTCTCTACGACACCGTTATCGTGTTCGACAAAGTTGAGGAGAATACCCACGGTTTCCAGCACACCACTCGGCGCACCTTCGCTGAGCAGGCTAACTTGGCGATCAATCAGACCTTCATGCGTTCGATCAACACCAGCCTGATCTCGGTACTACCGGTGTTGGCGCTGATGGTGGTCGCGGTGTGGTTGCTGGGCGTCGGTACGCTCAAGGACCTGGCATTAGTGCAGCTGGTCGGCATCATTGTCGGCACCTACTCGTCGATCTTCTTTGCAACTCCACTGTTGGTCACGCTGCGTGAACGCACAGAGCTGGTACGCACCCACACCCGCCGGGTAGTCAAACGGCGCACCCTCGGTTCGCAAGTGGGCAAAAAAAACGCTGACAGCCACGTTGCAGCAGGCACCCGAAAACCGCAGAATCAAGCGGAATCCTGCGCTGACGCATCGTCGCAGGAGGGCACCGAGGTCGCCACCGCGTCCGTGCCCACGGTACTCAGCAAGCTGGCACCGGGAGTGCGTCCGGTGCGGCCGACCGGTACCCGACGTCCTACCGGCAAGCGAAACAACGTCGGTCGGCGGTAGT

Protein Sequence 

>ML0488_SecF_protein
WSPEPKSAPRPPRVSTNQTEMTTPTTMAPVRSKSPKPPRMPWS_LTIYPHSCRSTAFLLGSTPAFLDCTPAPVCSRWWDAGGCGTAWAASSWRLRSCPLSFAGLLSGLISRAAPRCPCLSRPEWGGQAQLRLRRLPMSSRRPLAVIRNRWSLLVTARQQRCGSVRKRCPMTRRRSCVTPCLTHSDPKAPTLSLASRQSATRRYRRPGAVRSPRRW_SLLWCFWC_SACTSLCGTSVIWLSPH_LPCVLT_PSQPACTRWWASKSLRPLSSAC_RSSVSLSTTPLSCSTKLRRIPTVSSTPLGAPSLSRLTWRSIRPSCVRSTPA_SRYYRCWR_WWSRCGCWASVRSRTWH_CSWSASLSAPTRRSSLQLHCWSRCVNAQSWYAPTPAG_SNGAPSVRKWAKKTLTATLQQAPENRRIKRNPALTHRRRRAPRSPPRPCPRYSASWHRECVRCGRPVPDVLPASETTSVGGS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding SecF with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

7 show intermediate predicted evidence for PPIs

91 show weak predicted evidence for PPIs

View all pooled AlphaFold results for SecF

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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