ML0489
mL0489
Possible conserved lipoprotein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 593295 – 594962
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0489_ML0489_dna
TGCGGTCCGGCTTATTCGGGGTTTTGCGGTGGACTGCAGTAGGCTTGGTCGCGACGCTGGTGGCTTCTTTGGCGCTGACTGCGTGTTCTGGAAGCGCCGCGGGGGAGATCGTCTATGTGGTCGACGGGGCGTTGGGTACCTACAACACTAACACCATCGTCGGTGCTGCGTCGGCCGGAGCGCAGGCGTTTGCCCGCACGCTCATCGGCTTCGGCTATCACGGCCCCGATGGACAGATAGTCGCTGACCACGACTTCGGAACCATCACGGTGGTGGGCGGGGTGCCATTAGTGCTCGACTACCAGATAGCCGACAATGCTGTCTACTCCGACGGCAAGCAGGTGACTTGCGATGATTTGGTGCTGACCTGGGCTGCCCAGTCTGGGCGGTTTCCCGGCTTCGATGCTGCCACCCAGGCCGGTTACCGCGACATTGCTAATATCGAGTGCCTGGCCGGGCAGAAGAAATCCCGCGTGTTCTTCGTCCCGGACCGCAGCGTTGTCGATTATGAACAGCTGTTCGCCGCGACCTCGATGATGCCGTCACACGTCATCGCTGACCAACTGAATATCGACGTGACGGAGGCATTGCTGACCCACAATGCGACATTGGTGGAACAGATCGCGCGATTGTGGAACACCACCTGGGACCTCAAACCAGCTGTCGATTTGAGACGCTTCCCGTCGTCAGGCCCATACAAGATCGAATCCGTCTTGAACGGTGGCGCTGTAGTGCTTGTAGCCAACGACCGTTGGTGGGGTCTCAAGGCGACCACCAAGCGGATCACAGTACGGCCACAGGAAGCCGACATCCAGGACCGAGTCAACAACCGCAGCGTCGACGTCGTCGATGTCGCGGTCGGGTCGTCGGGATCGCTGGCCACTCCGGACAATTACGCGCGCATCGACTCGCCGTCGGCGGGCATCGAGCAGCTGATCTTTGCGCCGCAGGGGCTGCTGGCTGCGGCTGCCGCCCGCCGCGCACTCGCGCTGTGTACGCCCCGCGACGTGGTCGCTCGAGACGCGGGGTTGTCGATCGCCAACTCACGCCTGTCCCCGGCTACCGAGGATGCCATCGCTGCGGCCGACGGTGCTCGCGAGGCCGGCCAGTTCAGCAAGGCGGATCCCGCCGCAGCGCACGACGCACTTAGTGGTGAGACGTTGCCGGTGCGGATCGGCTACCAAGGGCCCAACGCACGGTTGGCGGCCACCGTCGGGACTATCGCCAAGGCGTGCGCTGTAGCTGGTATCAGTGTGTCCAGCGTTACCTTGGACTCCTCGACGGACCCCTCGGGCCCGCAGGCGCTTCGGGACGGAAAGATCGACGTGCTGTTGGCCAGCACTGGTGGCGCCACCGGCAGCGGATCGAGTGGGTCATCTTCGATGGATGCCTATGACCTACACACCGGCAACGGCAACAACCTGTCTGGCTATGCAAACGCGCAGGTTGACAACAATATCGGCGCGTTGGCGGTATCCGCTGACCCAGCCGAGCGTGTTCGGCTCCTCGCCGATAGTGCACCTGTACTCTGGGCGGATATGCCGACATTGCCTCTATACCGGCAGCAGCGAATGCTGCTGATGTCGAAGACAATGTATGCAGTTACCAGGAATCCGACCCGTTGGGGCGCGGGTTGGAACATGGATCGATGGGCGTTAGTACGATGAA

Protein Sequence 

>ML0489_ML0489_protein
CGPAYSGFCGGLQ_AWSRRWWLLWR_LRVLEAPRGRSSMWSTGRWVPTTLTPSSVLRRPERRRLPARSSASAITAPMDR_SLTTTSEPSRWWAGCH_CSTTR_PTMLSTPTASR_LAMIWC_PGLPSLGGFPASMLPPRPVTATLLISSAWPGRRNPACSSSRTAALSIMNSCSPRPR_CRHTSSLTN_IST_RRHC_PTMRHWWNRSRDCGTPPGTSNQLSI_DASRRQAHTRSNPS_TVAL_CL_PTTVGGVSRRPPSGSQYGHRKPTSRTESTTAASTSSMSRSGRRDRWPLRTITRASTRRRRASSS_SLRRRGCWLRLPPAAHSRCVRPATWSLETRGCRSPTHACPRLPRMPSLRPTVLARPASSARRIPPQRTTHLVVRRCRCGSATKGPTHGWRPPSGLSPRRAL_LVSVCPALPWTPRRTPRARRRFGTERSTCCWPALVAPPAADRVGHLRWMPMTYTPATATTCLAMQTRRLTTISARWRYPLTQPSVFGSSPIVHLYSGRICRHCLYTGSSECC_CRRQCMQLPGIRPVGARVGTWIDGR_YDE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML0489 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

21 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML0489

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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