ppiB
mL0492c
Probable peptidyl-prolyl cis-trans isomerase B PpiB (Cyclopphilin) (Ppiase) (Rotamase) (Peptidylprolyl isomerase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 598030 – 598917
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0492c_ppiB_dna
CGTGCCGACCAACGAACAGCGACGCGCAACAGCCAAGCGCAAACTGAAACGACAGCTGGAGCGCCGCGCTAAGCAGGCCCGATGGCGCCGAGTCCTGTTGATAAGCGGTGGCGTGGTAGTGGCAGTGGCCGTAATTATTACGGTAGTGGCTACCGTCGTGATCAGCAAGCTTGGCCACAAGCACGATACCGCTTCGTCGACCGCCAGTAACTCCCTGACAGCGACTAAGACTCCCGCCGTTACGCCGTCAGTTCTGCCATTGCCATCATTCCAACCGTCGACCAACCTGGGCGTCAACTGCCAGTACCCACCATCAGCGGACAAGGCCGCCAAGCCAGTCAAGCCGCCACGGGCCGGCAAGGTGCCGACCGATCCAGCCACAGTGAGCGCAAGTATGGCTACCAACCAGGGCAATATCGGTCTATTGCTAAACAATGCCGAATCACCTTGCACGGTAAATAGTTTCGCCAGTCTAACCGGCCAGGGCTTTTTCAACAACACAAAATGTCATAGGTTGACCACTTCCCTGATGCTGGGCGTCTTACAGTGTGGCGACCCGAAAGTCGACGGCACCGGCGGCCCAGGATACAAGTTCGCTAACGAGTACCCCACAGATCAGTACCCGCCCAACGACCCTAAATTGAAGCAACCTGTTCTGTATCCGCGTGGCACACTGGCAATGGCCAATAGCGGTCCGAACACCAATGGCAGCCAATTTTTTCTAGTCTACCATGACTCACAGTTACCGCCTGAGTACACCGTCTTCGGCACGATCCAGGCTGACGGGCTGGCCACGCTGGACAAGATAGCTAAGGGCGGAATCGCCAGCGGCGGTGATGACGGGCCACCAGCCACCGAAGTTACCATCGAGTCGCTGCGGCTCGACTA

Protein Sequence 

>ML0492c_PpiB_protein
RADQRTATRNSQAQTETTAGAPR_AGPMAPSPVDKRWRGSGSGRNYYGSGYRRDQQAWPQARYRFVDRQ_LPDSD_DSRRYAVSSAIAIIPTVDQPGRQLPVPTISGQGRQASQAATGRQGADRSSHSERKYGYQPGQYRSIAKQCRITLHGK_FRQSNRPGLFQQHKMS_VDHFPDAGRLTVWRPESRRHRRPRIQVR_RVPHRSVPAQRP_IEATCSVSAWHTGNGQ_RSEHQWQPIFSSLP_LTVTA_VHRLRHDPG_RAGHAGQDS_GRNRQRR__RATSHRSYHRVAAARL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PpiB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

38 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PpiB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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