aroK
mL0517
Shikimate kinase AroK (SK)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 628973 – 629572
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0517_aroK_dna
TGGCACCCAAGGCAGTACTCGTGGGTCTGCCAGGAGCCGGCAAGTCCACCATCGGGCGGCGACTGTCCAAGGCGCTAGGGGTGAGCTTGCTCGATACCGACGCTGCTATTGAGAAGCAGACCGGTCGCAGCATCGCTGACATCTTTGCCATCGACGGGGAAGAAGAGTTCCGCCGCATCGAAGAGGGCGTGGTGCGGGCTGCTTTAGTCGAGCATGACGGTGTGGTGTCGCTTGGCGGCGGTGCTGTCACTAGCCCAGGGGTATGCGCGGCGCTCGCTGGCCACATTGTCATCTATCTGGAGATCAACGCCGAAGAAGCAATGCGGCGTGCCTGTGGCAGTACCGTGCGACCGTTGCTGGCCGGGCCCGACCGTGCTGAAAAATTCCAGGATCTGATGGCCAGACGGGTTCCTCTTTACCGGCGAGTTGCGACTATCCGGGTTGATACCAACTGCCACAATCTGGGGGCGGTAGTCCGCTACATCATGGCCCGGTTGCAGGCTCAACTAGCCACTCCTGTCTCTGGTGGTGATCGCAAGAGTAGCGAAGCCGAGCGTAGTGGGGCGCCACTTCGCAAATCTAGTGAGGTCGTCAAATGAC

Protein Sequence 

>ML0517_AroK_protein
WHPRQYSWVCQEPASPPSGGDCPRR_G_ACSIPTLLLRSRPVAASLTSLPSTGKKSSAASKRAWCGLL_SSMTVWCRLAAVLSLAQGYARRSLATLSSIWRSTPKKQCGVPVAVPCDRCWPGPTVLKNSRI_WPDGFLFTGELRLSGLIPTATIWGR_SATSWPGCRLN_PLLSLVVIARVAKPSVVGRHFANLVRSSND

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding AroK with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

26 show weak predicted evidence for PPIs

View all pooled AlphaFold results for AroK

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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