aroB
mL0518
3-dehydroquinate synthase AroB
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 629569 – 630654
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0518_aroB_dna
TGACAAATATCGACGCACCGGTCACTGTGCAGGTGGCTGTCGACCCGCCATACCCAGTGGTGATCGGCACCGGGTTGTCGGATCAATTGGATGAACTGCTTGCCAACCGACATCGGGTCGCGATACTGCATCAACCGGTACTGACCCAAACTGCGGAGGCGATCCGAAGCCACTTGGCCGGCAAGGGGGTCGACGCGCACCGCATCGAAATACCTGACGCCGAGGCCGGCAAGGATCTTTCTGTCATGGATTTCATATGGGAAGTATTGGGCCGCATCGGAATTGGACGTAAAGATGCACTGGTCAGTTTTGGCGGCGGCGCCGCTACCGATGTAGCTGGGTTCGCGGCGGCTACCTGGTTACGCGGTGTCTCTATCGTACATGTGCCGACCACGTTGTTAGGTATGGTCGACGCAGCGGTTGGGGGCAAGACTGGTATCAACACCGAGGCTGGCAAGAACCTGGTCGGCGCATTTCATCAACCTCTCGCCGTGTTGGCTGACCTGGCGACTTTGGAAACTTTGCCGCGCAAAGAAATTGCGTCCGGTATGGCCGAAGTAGTCAAGGCCGGATTTATTGCTGACCCGATCATCCTCGACCTCATCGAAGCCGACCCACAGGCCTCCTTGGACCCGATGGGTGGCGTGTTGCCGGAGCTGATCCGCCGGGCCGTCACCGTCAAGGCGGGCGTCGTCTCCGCCGATGAGAAGGAATCCGAGTTGCGCGAAATCCTGAACTATGGCCACACTTTGGCACACGCAATCGAGCGCCGGGAGCGCTATGAATGGCGTCATGGCGCCGCCGTGTCGGTGGGCTTGGTGTTCGCAGCCGAACTGGCCCGAGTTGCGGGGCGGCTCGACGATGCCACGGCGCAGCGACATCACACCATTCTGACCTCGCTTGGCTTGCCGGTCAGCTATGACGCTGATGCGTTGCCGCAGCTGCTGGAATATATGGCCGGGGACAAGAAAACCCGGGCTGGCGTGCTTAGATTCGTGATCCTCGATGGGCTGGCTAAGCCGGGGCGGTTAGTGGGGCCGGACCCAGGGCTGTTAGTGACTGCTTACGCAGGATTGAGTGCCTGAT

Protein Sequence 

>ML0518_AroB_protein
QISTHRSLCRWLSTRHTQW_SAPGCRINWMNCLPTDIGSRYCINRY_PKLRRRSEATWPARGSTRTASKYLTPRPARIFLSWISYGKYWAASELDVKMHWSVLAAAPLPM_LGSRRLPGYAVSLSYMCRPRC_VWSTQRLGARLVSTPRLARTWSAHFINLSPCWLTWRLWKLCRAKKLRPVWPK_SRPDLLLTRSSSTSSKPTHRPPWTRWVACCRS_SAGPSPSRRASSPPMRRNPSCAKS_TMATLWHTQSSAGSAMNGVMAPPCRWAWCSQPNWPELRGGSTMPRRSDITPF_PRLACRSAMTLMRCRSCWNIWPGTRKPGLACLDS_SSMGWLSRGG_WGRTQGC__LLTQD_VPD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding AroB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

29 show weak predicted evidence for PPIs

View all pooled AlphaFold results for AroB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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