pyrF
mL0537
Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 652995 – 653843
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0537_pyrF_dna
TGACCGGTTTTGGCGCTCGGCTGGTCGAGGCGACGTCACGCCGCGGGCAGCTGTGTTTGGGTATAGACCCGCATCCTGAGTTGCTGCGCGCATGGGACTTGCCGACTACCGCGGACGGGCTGGCTGCGTTCTGCGACATCTGTGTGGAGGCGTTTTCCGGTTTCGCCATAGTCAAACCACAGGTGGCGTTTTTTGAAGCCTACGGCGCTGCCGGCTTCGCGGTGCTGGAGTATACCATCGCCGCGTTGCGGTCTGTCGGCGTACTGGTGTTGGCTGACGCCAAACGAGGGGATATCGGGTCGACGATGGCGGCCTACGCTGCTGCTTGGGCAGGCAATTCGCCGTTGGCCGCCGACGCGGTGACGGCCTCGCCGTATCTTGGGTTCGGCTCGTTGCGGCCGCTACTAGAAGTAGCCGCGGCACACGACCGGGGCGTGTTCGTGCTAGCATCAACGTCCAACCTTGAGGGTGCCACCGTCCAGCGCGCCACGTTTGACGGTCGCATAGTAGCTCAACTGATTGTTGACCAGGCGGCTTTCGTCAACAGAGAAATGAACCGGTCCTTCCATCGGTCTGAGCCGGGGTGCTTGGGATATGTTGGAGTAGTCGTAGGCGCAACGGTTTTCGGGGCGCCGGATGTCAGCGCGCTGGGTGGACCGGTGTTGGTGCCCGGAGTGGGGGCGCAGGGTGGACACCCCGAGGCGCTCGGCGGCCTGGGTGGGGCGGCGCCAGGTCAGCTGTTGCCTGCGGTGTCACGTGCAGTGTTGCGCGCCGGCCCCGGTGTTTCAGAGCTGCGAGCAGCTGGCGAACAGATGCGTGATGCAGTCGCCTATCTCGCTGCTGTTTAGT

Protein Sequence 

>ML0537_PyrF_protein
PVLALGWSRRRHAAGSCVWV_TRILSCCAHGTCRLPRTGWLRSATSVWRRFPVSP_SNHRWRFLKPTALPASRCWSIPSPRCGLSAYWCWLTPNEGISGRRWRPTLLLGQAIRRWPPTR_RPRRILGSARCGRY_K_PRHTTGACSC_HQRPTLRVPPSSAPRLTVA__LN_LLTRRLSSTEK_TGPSIGLSRGAWDMLE_S_AQRFSGRRMSARWVDRCWCPEWGRRVDTPRRSAAWVGRRQVSCCLRCHVQCCAPAPVFQSCEQLANRCVMQSPISLLFS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PyrF with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

8 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PyrF

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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