rpoZ
mL0542
Probable DNA-directed RNA polymerase omega chain RpoZ (Transcriptase omega chain) (RNA polymerase omega subunit)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 657981 – 658313
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0542_rpoZ_dna
TGAGTATTCCGCAGTCCAACACGTCTTTGAGCGCTGTCATTGCCGTGGATCAGTTTGATCCATCGTCAGGTGGGCAAGGCGTTTACGACACCCCTCTGGGCATCACCAACCCACCTATCGACGAGTTGCTGGACCGTGTCTCAAGCAAATACGCCCTGGTGATCTACGCGGCCAAGCGGGCGCGCCAGATTAACGACCACTACAATCAGCTCGGCGAGGGCATCCTCGAATACGTTGGTCCGCTGGTGGAGCCTGGGCTGCAGGAGAAACCGTTGTCCATCGCGATGCGCGAGATTCACGCCGATCTGCTCGAGCACACCGAGGGCGAGTAAA

Protein Sequence 

>ML0542_RpoZ_protein
VFRSPTRL_ALSLPWISLIHRQVGKAFTTPLWASPTHLSTSCWTVSQANTPW_STRPSGRARLTTTTISSARASSNTLVRWWSLGCRRNRCPSRCARFTPICSSTPRASK

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding RpoZ with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

65 show weak predicted evidence for PPIs

View all pooled AlphaFold results for RpoZ

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.