tpi
mL0572
Probable triosephosphate isomerase Tpi (TIM)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 697159 – 697944
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0572_tpi_dna
TGAGCCGCAAGTCGCTCATCGCCGGCAACTGGAAGATGAACCTGAATCATTTCGAGGCGATTGCGTTGGTGCAAAAAATCGCTTTTTCATTGCCGGACAAGTATTATGACAAGGTTGATGTCACAGTTCTTCCGCCATTCACTGACCTGCGTAGCGTGCAAACCCTGGTCGATGGCGATAAGTTGCGATTGACCTATGGTGCCCAGGATCTTTCGCAACATGACCTAGGCGCCTACACTGGAGACATCAGTGGGGCCTTCTTGGCTAAGTTGGGCTGTAGCTTCGTGCTGGTGGGGCACTCTGAGCGGCGCACCTACCACGACGAAGGTGACGCGCTGGTGGCCGCGAAGACGGCTGCGGCGCTCAAAAACAGCTTGACTCCGATCGTGTGCATCGGCGAGTACCTCGAGATCCGAGAGGTGGGTGAACACGTCAGCCACTGCCAGAACCAGCTACGCGGCTCGCTGGCTGGGCTGTCGCCTGAACAGATCGGCAATGTCGTGATCGTTTATGAACCGGTCTGGGCGATCGGGACTGGGCGGGTGGCTAGTGCAGCCGACGCCCAAGAGGTGTGCGAGGCGATCCGAAAAGAGCTGGGTGCGCTGGCATCACCGCAGGTGGCCGAAACCGTTCGGGTGCTTTATGGTGGCTCGTTGAACGCCAAAAACATTGGCGATATCGTCGCCCAGCAAGACGTCGATGGTGGTCTGGTTGGGGGAGCGTCGCTGGACGGGGCGCAATTCGCGACGCTCGCGGTCATCGCCGCCGGTGGGCCTCTTCCCTAGG

Protein Sequence 

>ML0572_Tpi_protein
AASRSSPATGR_T_IISRRLRWCKKSLFHCRTSIMTRLMSQFFRHSLTCVACKPWSMAISCD_PMVPRIFRNMT_APTLETSVGPSWLSWAVASCWWGTLSGAPTTTKVTRWWPRRRLRRSKTA_LRSCASASTSRSERWVNTSATARTSYAARWLGCRLNRSAMS_SFMNRSGRSGLGGWLVQPTPKRCARRSEKSWVRWHHRRWPKPFGCFMVAR_TPKTLAISSPSKTSMVVWLGERRWTGRNSRRSRSSPPVGLFPR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Tpi with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

14 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Tpi

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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