ML0591c
mL0591c
Possible conserved integral membrane protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 715976 – 717757
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0591c_ML0591c_dna
GATGGCAGCCCGCCACCACACACTGAGCTCATCCATCGCCAGCTTGCATGGTGATGAGCAGGCAGTGGGCTCACCACTGAACGATGCCGACCGTGGCGCACTACAGCGCACCCGCTTGTTTGGGGCTACCGGCACCATCCTGATGGCGATTGGCGCGCTCGGAGCAGGGGCCAGGCCCGTCATCCAGGACCCCACGTTCGGGGTTCGGCTGCTCAATCTGCCGTCAAGAATCCAGACGGTCTCGTTGACGATGACTACAACCGGGGCGGTCATGATGACGCTGGCCTGGTTGATGCTCGGCCGGTTCGCGCTGGGCAGGAGACAGATGTCGCGCGGCGAGCTGGACCGCACCCTGTTGCTGTGGACGCTGCCGCTATTGATTGCACCACCGATGTACAGCAAGGATGTCTACTCCTACCTCGCGCAAAGCCAGATCTCCCTACAGGGACTCGACCCTTACCGGGTAGGTCCGGCGTCCGCACTGGGACTAGGCCAGGTGTTCACGCTTTCGGTACCCAGCCTATGGCGGGAAACACCCGCACCCTACGGCCCACTGTTTTTGTGGATCGGGCGCGGAATCTCAGCACTGACCGGAGACAACATCGTCGCCGCGGTACTCTGCCACCGGTTGATGATGTTAATCGGCGTCGGCCTGGTCGTGTGGGCAACCCCGCAACTGGCCCGACGCTGCGGCGTGGTCGAGGTTAGCGCGTTATGGCTAGGTGCAGCCAACCCACTGCTAATCATGCATCTAGTCGCCGGCATCCACAACGAGGCACCGATGCTAGGGCTTATGCTCACAGGGGCCGAATTCGCTCTGCGTGGCATTGACTTCTCGTCCACAACACGAGTGATACCCACCTCCTGGCGCGGTGGAGGTACCGGCAGGCAACACAGCGGCACGCTTACAAGCCAGGCAATCCGGTTCGGCTCGAATTGGGAGCCGCTGGGCATGTTGCTGGCCGGTTCGATCCTGATCGTACTGTCTTCACAAGTGAAGCTGCCGTCGCTGCTGGCACTGGGATTCGTCGCGATGGCGCTAGCCTGCCGACTTGGCAGTACCCCGCAAGCACTGCTAATGGTCAGCTTGTGGATGGCAGGATTGTCTCTGGCAGTGATGGGCATCGTTGGCTGGGCCAGTGGACTCGGGTTTGGCTGGATCTACACGTTGGGCACCGCAAACGTAGTACGCAGCTGGATGTCACCGCCGACGCTACTAGCTCTCGGTACCGGGCACGTGGGTATTCTGCTGGGTCTGGGGGATCACACCACTGCAGTGCTGTCGTTGACCCGCGGCATCGGCGTACTGATCATCATGGTCATGGCCTGTTGGTTGTTGCTAGCTGTGTTCCGCGGTCGGCTACACCCGATCGGCGGCCTCGGCGTCGCGCTGGGCGTCACGGTGTTGCTGTTTCCCGTCGTGCAACCCTGGTATCTGCTGTGGGCCATCATTCCGCTAGCCGCCTGGGCGACCCGCACCGGCTTCCGAGTGGCTGCAATCACCGTCACCATCGTCGTGGGCGTCTTCGGCCCTACGGCCAACGGTGATCGTTTCGCGCTGTTCCAAATTGTGGATGCCACCGTGGCCAGCACCATCATCGTGTTGGTGCTCATTGCACTAACCTACACCCGCTTGCCATGGCGACCACTCCAGATGGTCCCAGCCAAGAGGAGCGAACTGGATCAACAACTGGTGAGGGTTGTTGCACCGGACCCGGAGACCTCGCAGAACTCCGCGTCTCCTGCGACCCGGCTGCCGACCGCCTACGCTAACTTAACATG

Protein Sequence 

>ML0591c_ML0591c_protein
DGSPPPHTELIHRQLAW__AGSGLTTERCRPWRTTAHPLVWGYRHHPDGDWRARSRGQARHPGPHVRGSAAQSAVKNPDGLVDDDYNRGGHDDAGLVDARPVRAGQETDVARRAGPHPVAVDAAAIDCTTDVQQGCLLLPRAKPDLPTGTRPLPGRSGVRTGTRPGVHAFGTQPMAGNTRTLRPTVFVDRARNLSTDRRQHRRRGTLPPVDDVNRRRPGRVGNPATGPTLRRGRG_RVMARCSQPTANHASSRRHPQRGTDARAYAHRGRIRSAWH_LLVHNTSDTHLLARWRYRQATQRHAYKPGNPVRLELGAAGHVAGRFDPDRTVFTSEAAVAAGTGIRRDGASLPTWQYPASTANGQLVDGRIVSGSDGHRWLGQWTRVWLDLHVGHRKRSTQLDVTADATSSRYRARGYSAGSGGSHHCSAVVDPRHRRTDHHGHGLLVVASCVPRSATPDRRPRRRAGRHGVAVSRRATLVSAVGHHSASRLGDPHRLPSGCNHRHHRRGRLRPYGQR_SFRAVPNCGCHRGQHHHRVGAHCTNLHPLAMATTPDGPSQEERTGSTTGEGCCTGPGDLAELRVSCDPAADRLR_LNM

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML0591c with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

3 proteins show strong predicted evidence for PPIs

7 show intermediate predicted evidence for PPIs

89 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML0591c

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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