lepA
mL0611
Probable GTP-binding protein LepA
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 742717 – 744657
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0611_lepA_dna
TGTCTTGGTCACTTCGCGTGGATAAGCCGGACACCGGCGAATCGCCGTTCAAACATTCTCTAGTAACTGGAGCCCAGGAGATTCCCATCAGCAGTTTCGCTGACAAGACCTTTACCGCGCCGGCGCAGATTAGGAACTTCTGCATAATCGCTCATATTGATCACGGCAAATCCACGCTGGCGGACCGGATGCTTCAGCTGACTGGTGTCGTCGATGAGCGGTCGATGCGTGCCCAGTACCTGGACCGGATGGACATCGAACGTGAGCGCGGAATCACGATTAAAGCGCAGAACGTGCGGCTGTCTTGGAGTGTCACAGCTGGTGGGACGACTGAGAATTATGTGTTGCACTTGATCGACACCCCCGGCCATGTGGACTTCACCTACGAGGTATCGCGAGCATTGGAAGCCTGTGAGGGTGCGGTGCTGCTGGTAGACGCCGTCCAGGGCATCGAAGCTCAGACCTTGGCCAATCTCTATCTCGCTCTGGAGCGTGACTTGACGATTATTCCGGTGCTAAACAAAATCGACCTGCCGGCTGCCGATCCGGACCGTTACGCCGCTGAGATCGCCCACATCATTGGTTATGAGTCAGGCGATGTGCTTCGGGTGTCCGGCAAAACCGGCGAGGGGGTTTCTGACCTTCTTGACGAGGTGGTCCGTCGGGTGCCGCATCCGCAAGGTGACCCTGATGCGCCTACCCGCGCGATGATCTTCGACTCCGTCTACGACATCTACCGAGGCGTGGTCACCTACGTCCGTGTGGTCGACGGCAAGATCAGCCCGCGTGAGCGCATCGCGATGATGTCCACCGGTGCGACGTACGAACTGCTCGAGGTCGGCATCGTGTCGCCTGAACCGAAGGCCAGCGCGGGCCTGGGCGTGGGGGAGGTGGGCTACCTGATTACTGGGGTTAAAGACGTCCGCCAATCCAAAGTCGGCGACACTGTAACGACGGTTCGTTATGGTGCCACTGAACCGTTAACTGGCTACCGAGAACCCAAGCCCATGGTGTACTCCGGGCTGTATCCCGTCGACAGTTCGGACTACCCGAGTTTGCGTGACGCTCTAGGTAAGTTACAGCTCAACGACGCGGCGCTGACCTACGAGCCGGAAACATCGGTGGCGCTGGGCGTTGGGTACCGGTGCGGCTTCCTCGGTTTGCTGCACATAGATATAACCCGCGAACGCTTAGAGCGCGAGTTCGACCTGGACCTGATCTCCACGTCGCCCAACGTCGTATACCGTGTGGTGACAGAAGATAACACCGAGATTGTGGTGACCAACCCGTCAGACTGGCCGGAGGGCAAGATCCGAACGGTGTACGAGCCAGTGGTGAAGATCACCATCATTGCGCCCAGCGAGTTCATCGGAACGATCATGGAGCTGTGCCAGTCGCGCCGTGGCGAATTAGGTGGCATGGACTATCTTTCACCTGAGCGAGTCGAGTTACGCTACATTATGCCGCTCGGGGAAATCATCTTCGATTTCTTCGATTCGCTGAAGTCACGCACCCGGGGCTACGCTAGCCTCGACTATGAGGAGGCTGGCGAGCAGGAGGCCCAACTGGTCAAGGTTGACATCCTGCTGCAAGGCGAGGCCGTCGACGCATTCAGCGCGATTGTGCACAAGGATTCAGCCTCTGCCTATGGCAACAAGATGACCAACAAGCTCAAAGAACTGATCCCACGTCAGCAGTTTGAGGTGCCAGTACAGGCGGCTATTGGATCGAAAGTCATTGCGCGCGAAAATATTAGGGCGATACGCAAGGATGTGCTGTCGAAATGTTATGGCGGCGATATCACCCGCAAACGTAAGCTTCTGGAAAAGCAGAAGGAAGGCAAGAAACGGATGAAGACCATTGGGCGGGTCGAGGTGCCGCAGGAAGCGTTTGTCGCCGCGTTGTCCGCCGATGCCGCAGGAGACAAGGACAAGAAATAAC

Protein Sequence 

>ML0611_LepA_protein
CLGHFAWISRTPANRRSNIL__LEPRRFPSAVSLTRPLPRRRRLGTSA_SLILITANPRWRTGCFS_LVSSMSGRCVPSTWTGWTSNVSAESRLKRRTCGCLGVSQLVGRLRIMCCT_STPPAMWTSPTRYREHWKPVRVRCCW_TPSRASKLRPWPISISLWSVT_RLFRC_TKSTCRLPIRTVTPLRSPTSLVMSQAMCFGCPAKPARGFLTFLTRWSVGCRIRKVTLMRLPAR_SSTPSTTSTEAWSPTSVWSTARSARVSASR_CPPVRRTNCSRSASCRLNRRPARAWAWGRWAT_LLGLKTSANPKSATL_RRFVMVPLNR_LATENPSPWCTPGCIPSTVRTTRVCVTL_VSYSSTTRR_PTSRKHRWRWALGTGAASSVCCT_I_PANA_SASSTWT_SPRRPTSYTVW_QKITPRLW_PTRQTGRRARSERCTSQW_RSPSLRPASSSERSWSCASRAVAN_VAWTIFHLSESSYATLCRSGKSSSISSIR_SHAPGATLASTMRRLASRRPNWSRLTSCCKARPSTHSARLCTRIQPLPMATR_PTSSKN_SHVSSLRCQYRRLLDRKSLRAKILGRYARMCCRNVMAAISPANVSFWKSRRKARNG_RPLGGSRCRRKRLSPRCPPMPQETRTRNN

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding LepA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

72 show weak predicted evidence for PPIs

View all pooled AlphaFold results for LepA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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