hrcA
mL0624
Probable heat-inducible transcription repressor HrcA
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 756771 – 757802
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0624_hrcA_dna
TGGGGAATGCCGACGAGCGTCGCTTTGAGGTGCTGCGCGCCATTGTAGCCGACTTCGTCGCCACCAAGGAACCGATCGGATCGAGGGCTTTGGTGGAGCGTCACAACTTAGGCGTGTCCAGCGCAACCATCCGCAACGACATGGCGGTGTTAGAGGCCGAGGGGTACATCACTCAGCCGCATACCAGCTCCGGGCGAGTGCCCACGGAGAAGGGCTATCGCGAGTTTGTTGATCGACTCGAAGACGTTAAGCCGCTATCAGCGGCCGAGCGGCGGGCGATCCAAAGCTTTCTGGAGTCCGGTGTCGACCTCGACGACGTGCTACGCCGCGCTGTGCGACTATTGGCTCAGCTGACCTGTCAGGTGGCCGTGGTGCAGTACCCCACCTTGTCGACGTCGACCGTTCGCCATCTGGAAGTAATCGCGCTGAGCCCGGCCAGGTTGCTGATGGTGGTTATCACCGAGTCCGGTCGGGTGGATCAGCGCATCGCCGAACTCGGCGATGTTATCGACGATTACCAGCTCTCCCAGCTGCGTGAAATGCTCAGCCAGGCAATGGGAGGCAAGAAACTGTCGGCGGCCTCGGCCGCGGTAGCCGACCTCGTCGGACGGTTTCGGGGTACGGGCGGGTTGGCCAATGCCGTCGGCCGCTCGGCGAACGTATTGCTGGAATCGCTAGTCGAACACACCGAAGAACGCTTGTTGCTGGGTGGCACTGCCAACCTGACCCGCAACTCTGCGGACTTCGGTGGTTCACTGCGATCCATCTTGGAAGCCCTCGAAGAACAGGTGGTGGTGCTGCGACTGCTGGCCGCCCAACAGGAGGCTGGCAAGGTGACTGTGCGTATTGGTCACGAAACGGCGGCTGAGCAAATAATGGGTACCTCGATGGTGTCCACCGCCTACGGTACCTCGGGTACCGTCTACGGCGGCATGGGTGTGTTGGGGCCTACCCGGATGGATTATCCGGGAACTATCGCCAGTGTCGCTGCGGTTGCTTTGTATATCGGCGAAGTTTTGGGTGCTCGGTGAA

Protein Sequence 

>ML0624_HrcA_protein
WGMPTSVALRCCAPL_PTSSPPRNRSDRGLWWSVTT_ACPAQPSATTWRC_RPRGTSLSRIPAPGECPRRRAIASLLIDSKTLSRYQRPSGGRSKAFWSPVSTSTTCYAALCDYWLS_PVRWPWCSTPPCRRRPFAIWK_SR_ARPGC_WWLSPSPVGWISASPNSAMLSTITSSPSCVKCSARQWEARNCRRPRPR_PTSSDGFGVRAGWPMPSAARRTYCWNR_SNTPKNACCWVALPT_PATLRTSVVHCDPSWKPSKNRWWCCDCWPPNRRLAR_LCVLVTKRRLSK_WVPRWCPPPTVPRVPSTAAWVCWGLPGWIIRELSPVSLRLLCISAKFWVLGE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding HrcA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

18 show weak predicted evidence for PPIs

View all pooled AlphaFold results for HrcA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.