uvrD2
mL0637
Probable ATP-dependent DNA helicase II UvrD2
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 769119 – 771272
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0637_uvrD2_dna
TGGATCCTATGGTAATGGTCGTAAATCCATTGACTGCTGGACTGGATGACGAGCAGCGCGAGGCCGTGCTGGCTCCACGCGGACCTGTTTGTGTGCTCGCGGGAGCCGGAACGGGTAAAACCCGCACCATCACTCACCGCATTGCCCACCTTGTTGGTGCTGGTCACGTCGCCACTGGGCAGGTGCTGGCGGTGACATTCACCCAGCGTGCAGCGGCGGAGATGCGGTCCCGGTTGAGGGCGCTTGGCGCTGCCGTACAAGCCGTTTCGGATTTTGGCGTTGTGCGAGTCCTGACCTTTCATGCTGCCGCGCACCGCCAGTTGCGATATTTCTGGCCACGGGTGATCGGTGACACTGGCTGGCAGCTGTTGGACAGCAAGTTTGCCACCGTTGCGCGGGCGGCTAGTAGTGTCAGGCTGCATGCTGGCACTGATGACGTGTGTGACCTCGCCGGCGAGATTGAATGGGCTAAGGCCTCGCTGATTGGGCCCGAAGAATACGTGGCCGCCGTGGCCGCTATCGGTAGAGACACTCCGCTGGACGCCGCGCAAATCGCGAGTGTCTACGCTGCCTACGAAGCTCTTAAGGCCCGCGGCAATGGCGTCCCAGGGGTCACGCTGCTCGACTTCGATGATCTGCTGCTGCACACCGCCGCCGCGATCGAGAACGACGCAGCGGTAGCCGAGGAGTTCCGGGACCGTTACCGTTGTTTTGTAGTCGATGAGTACCAAGACGTCACCCCGCTACAGCAACGGGTGCTTTCGGCCTGGTTGGGTGATCGAGACGATCTGACTGTGGTCGGCGACGCCAACCAGACCATCTACTCGTTCACTGGGGCTTCACCTTGTTTCCTGCTTGACTTCCCCCGACGGTTTCCCGATGCCACGGTGGTGCGGCTGGAGCGCGACTACCGGTCTACTCCGCAGGTGGTGTCGCTTGCAAATCAGGTGATCGCAGCGGCTCATGGCCGGGTTGCGGACAGCAAATTTCAGCTGTCCGGCCAGCGTGAGCCGGGTCCGGCCGCGTCATTTCACGAGTATTCTGATGAGCCTGCTGAGGCCGCTGCCGTGGCAGCATCAATTGCTCGACTGATCGAATTCGGCACCTCGCCATCCGAGATCGCGGTGCTTTACCGGGTCAATGCGCAGTCCGAGGCGTACGAGGAGGCGTTGACCGAGGTGGGGATTGCCTATCAGGTCCGCGGCGGCGAGGGATTTTTCAACCGCCAGGAGATCAAACAGGCGCTACTAGCCCTGCAGCGTAGTGCGGAGCGCAGCTCCCAAACAGAACCGAACAGCCCATTGTCGGACGTGGTCCGCGGTGTTCTGGAGCCATTGGGGCTAACGGCTGAGAAACCGGTCGGCAGCCGCGCCCGGGATCGTTGGGAGGCGCTGACCGCATTGGCCGAACTGGCCGACGACGAAGTGGCTCAGCATCCGCGGCTGGATCTTCCGGGGTTGCTGGCCGAGCTGCGGTTGCGGGCCGATGCCCGGCACCCACCGGTGGTACAGGGCGTCACGTTGGCCTCATTGCATGCCGTTAAAGGACTTGAGTGGGATGCGGTGTTCTTAGTCGGATTGGCCGACGGAACACTACCCATCTCGCGTGCGTTGGCGCATGGTGCTGAAAGCGAGCCTGTCGAGGAAGAGCGTAGGCTGCTTTATGTTGGAATCACCAGGGCCCGAGTGTATTTGGCACTTAGCTGGGCGTTATCGCGAACTCCGGGTGGACGTCAGAGCCGCAAGCCGTCGCGGTTCCTCAACGACATCGCGCCACAGATGGGTCAAAATCCTGCGTCGAGCAGATCTCGGCGTAATCGGACCGCTACTTTGCGCTGCCGTATTTGCAAAAACGACCTGACCACGCCTGCGGCCGTCATGCTGCAGCGGTGTCAGATATGTGCCGCAGACGTTGACGAAGAATTGTTGCTGCAGCTCAAAGCGTGGCGGCTTAGCACTGCCAAGGAACAGAACGTGCCTGCTTACGTCGTTTTAACCGATAACACGTTGATTGCGATTGCTGAGTTGCTGCCCGCCGATGAGGCCGCGTTGATCGCTGTCCCGGGTATGAGTGTACGCAAAATTGAGCAATACGGGTCGGACGTGCTGCAGTTGGTTCGCTGCCGTGCCGTCGCGGTTAGGACGCAGACCTGAT

Protein Sequence 

>ML0637_UvrD2_protein
WILW_WS_IH_LLDWMTSSARPCWLHADLFVCSREPERVKPAPSLTALPTLLVLVTSPLGRCWR_HSPSVQRRRCGPG_GRLALPYKPFRILALCES_PFMLPRTASCDISGHG_SVTLAGSCWTASLPPLRGRLVVSGCMLALMTCVTSPARLNGLRPR_LGPKNTWPPWPLSVETLRWTPRKSRVSTLPTKLLRPAAMASQGSRCSTSMICCCTPPPRSRTTQR_PRSSGTVTVVL_SMSTKTSPRYSNGCFRPGWVIETI_LWSATPTRPSTRSLGLHLVSCLTSPDGFPMPRWCGWSATTGLLRRWCRLQIR_SQRLMAGLRTANFSCPASVSRVRPRHFTSILMSLLRPLPWQHQLLD_SNSAPRHPRSRCFTGSMRSPRRTRRR_PRWGLPIRSAAARDFSTARRSNRRY_PCSVVRSAAPKQNRTAHCRTWSAVFWSHWG_RLRNRSAAAPGIVGRR_PHWPNWPTTKWLSIRGWIFRGCWPSCGCGPMPGTHRWYRASRWPHCMPLKDLSGMRCS_SDWPTEHYPSRVRWRMVLKASLSRKSVGCFMLESPGPECIWHLAGRYRELRVDVRAASRRGSSTTSRHRWVKILRRADLGVIGPLLCAAVFAKTT_PRLRPSCCSGVRYVPQTLTKNCCCSSKRGGLALPRNRTCLLTSF_PITR_LRLLSCCPPMRPR_SLSRV_VYAKLSNTGRTCCSWFAAVPSRLGRRPD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding UvrD2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

54 show weak predicted evidence for PPIs

View all pooled AlphaFold results for UvrD2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.