ML0640c
mL0640c
Probable conserved ATP-binding protein ABC transporter
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 772069 – 773490
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0640c_ML0640c_dna
GATGATGCGGGTGAAAGCCCGAATGAATAATGAATGTAGCCGTTTGATCATTGATTGCCATATCACGTCCATGGCACGCTTCACCGTCATGGATGATAGACGTGTGGCAGACATCAAACGTGGTCAGGCTGCGCGCAACGCGAAGCTAGCTAGCATTCCGGTCGGCCTTGCCGGGCGGGCGGTGCTCGGGCTCGGGAAACGACTGACTGGCAAGTCGAAAGACGAGGTTAACACCAAGCTGATAGAGAAGACCGCCCACCAGTTGTTCAGTGTCCTGGGCGAGCTCAAGGGCGGGGCAATGAAGGTCGGCCAGGCATTGTCTGTGATGGAAGCCGCGATTCCTGAAGAGTACGGCGAGCCCTACCGCGAAGCCCTGACCAAGCTGCAAAAGGACGCCCCGCCGTTGCCGGTCAACAAGGTGCATCGGGTGCTCGACGCCCAGTTAGGCACCAAGTGGCGGGACCGGTTCAGCTCGTTCAACGACACCCCGGTGGCCTCGGCCAGCATCGGCCAGGTGCATAAAGCGGTATGGTCCTATGGCCGCGAAGTGGCGGTCAAAATCCAGTATCCGGGTGCTGATGAGGCGTTGCGCGCCGATCTCAAGACCATGCAGCGGATGGTTGGGATACTCAAACAGCTCTCTCCCGGTGCTGACATCCAAGGTGTGGTAGACGAATTAGTCGAACGCACCGAGATGGAACTAGATTATCGGTTGGAGGCTGACAACCAACGTGCTTTCGCCAAGGCGTATCAGGGCGACCCGCGCTTTGTGGTGCCAAACGTGGTGGCAAGCGCACCGAAAGTGATAATCCAGGAGTGGATCGATGGTGTTCCGATGGCCGAAATCATCCGTAACGGAACCGCCCAACAACGTGACCGTATGGGAAAACTGCTACTCGAACTCACCTTCGATTCGCCACGCCGATTGGAAATGCTGCACGGCGACGCTCACCCAGGCAATTTCATGCTGCTGTCCGACGGCCGGATGGGCGTCATCGACTTCGGCGCTATCGCGCCACTGCCTGGTGGTTTCCCGGTAGAGCTGGGAATGAGCATCCGATTGGCCCGGGACAAGAACTACAACCTCTTGCTGCAGACGATGGAGAAGGCCGGCTTAATCCAAAAAGGCCGACAGGTGTCTGTGCGCGACATTGACGAGATGATGCACCAGTACGTAGAACCGATCAAAGTCGAGGTTTTCCACTACACACGTAAATGGCTGCAACAGATAAGCCTAGACCGATCGGTGTCGCACATCAAGACGGCACGCCAGTTGGATCTGCCGGCTACACTGGCCCTGCCTATGCGGGTGATCGCGTCGGTGGGCGCGATCCTCTGCCAACTCGACGCGCATGTGCCGACCAAGGCTCTGACCGAGAAGTTGGTTCCCGGCTTCGCCGAGCCCGATACTGCCATCGTCTA

Protein Sequence 

>ML0640c_ML0640c_protein
DDAGESPNE__M_PFDH_LPYHVHGTLHRHG__TCGRHQTWSGCAQREAS_HSGRPCRAGGARARETTDWQVERRG_HQADREDRPPVVQCPGRAQGRGNEGRPGIVCDGSRDS_RVRRALPRSPDQAAKGRPAVAGQQGASGARRPVRHQVAGPVQLVQRHPGGLGQHRPGA_SGMVLWPRSGGQNPVSGC__GVARRSQDHAADGWDTQTALSRC_HPRCGRRISRTHRDGTRLSVGG_QPTCFRQGVSGRPALCGAKRGGKRTESDNPGVDRWCSDGRNHP_RNRPTT_PYGKTATRTHLRFATPIGNAARRRSPRQFHAAVRRPDGRHRLRRYRATAWWFPGRAGNEHPIGPGQELQPLAADDGEGRLNPKRPTGVCARH_RDDAPVRRTDQSRGFPLHT_MAATDKPRPIGVAHQDGTPVGSAGYTGPAYAGDRVGGRDPLPTRRACADQGSDREVGSRLRRARYCHRL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML0640c with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

40 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML0640c

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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