ML0643
mL0643
Possible conserved secreted protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 776009 – 777031
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0643_ML0643_dna
TGAACAGGCGGATTCTCACCTTGTTGGTTGCGCTGGTGCCGATTCTGGTCTTCGGCGTGTTGCTTGCGGTGGTGACGGTGCCGTTCGTGTCGCTGGGCCCCGGTCCCACTTTTGACACACTCGGTGAGGTGGACGGCAAGCAGGTCGTCGCGATCAAAGGCGCGCACACGCACCCGACGTCTGGTCATCTCAACATGACAACGGTGTCCCAGCGCGACGATCTGACCTTGGGTGAAGCCCTGACATTGTGGCTGTCCGGACAAGAACAGCTGGTGCCGCGCGACCTAATCTACCCGCCGGGAAAGTCGAGGGAAGACGTTGACAAGGTCAACTACGCTGATTTCAAACAGTCCGAGGACAGTGCAGCTTATGCCGCACTGGGATACCTGCAGTATCCGTCTGCAGTTACCGTTGCTAAAGTCACTGATCCTGGTCAGTCAGTGGGCAAACTGAAGTCTGGTGATGCCGTGGACGCGGTCAACGGCAGCCCGGTGGCCAATGTCGAGCAATTCACCGGATTGCTGAAGAAAACTAAGCCCGGCGAGGTGGTGACCATCGACTTTCGTCGCAAGAACGAGCCACCCGGTGTGGTACAGATAACATTGGGTGCGAACAAAGATCGCGACTACGGCTTTTTGGGTGTCGCGGTGCTAGATGCGCCGTGGGCGCCATTTGTGGTGGATTTCAACCTCGCCAACGTTGGCGGTCCCTCGGCCGGACTGATGTTCAGCCTGGCGGTTGTCGACAAGCTGACCACCGGCGACTTGGTCGGGTCTACGTTCGTCGCGGGCACCGGAACCATCAGCATCGACGGCAAGGTGGGCCCTATTGGAGGCATCGCGCACAAGATGGCTGCCGCCCGCGCTGCCGGCGCCACGGTGTTTCTAGTGCCCGCGAAGAACTGCTACGAGGCGCGCTCCGATAACCGCACCGGCCTGCGATTGGTTAAGGTCGAGAGCCTCAGCCAAGCCGTGGACGCGTTGCACGCTATGACGTCGGGGGGCCAGCTGCCGAGCTGCTAAT

Protein Sequence 

>ML0643_ML0643_protein
TGGFSPCWLRWCRFWSSACCLRW_RCRSCRWAPVPLLTHSVRWTASRSSRSKARTRTRRLVIST_QRCPSATI_PWVKP_HCGCPDKNSWCRAT_STRRESRGKTLTRSTTLISNSPRTVQLMPHWDTCSIRLQLPLLKSLILVSQWAN_SLVMPWTRSTAARWPMSSNSPDC_RKLSPARW_PSTFVARTSHPVWYR_HWVRTKIATTAFWVSRC_MRRGRHLWWISTSPTLAVPRPD_CSAWRLSTS_PPATWSGLRSSRAPEPSASTARWALLEASRTRWLPPALPAPRCF_CPRRTATRRAPITAPACDWLRSRASAKPWTRCTL_RRGASCRAAN

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML0643 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

73 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML0643

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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