ML0644
mL0644
Probable conserved transmembrane protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 777177 – 780128
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0644_ML0644_dna
TGGGGATGCGGCCCGCTGCAAGGATGCCGAAACTGACTCGGCGTAGCCGGACTCTGATCATGGTCGCACTGGGTGTGATCGTGTTGCTGCTTGCGGGTCCGCGACTGGTCGATGCGTACGTTGAGTGGCTGTGGTTCGGTGAGCTTGGCTACCGTTCGGTATTCAGTACTGTGCTGGTTACCCGCGTCGTGGTGTTCCTGGTAGCCGGGCTGGTGGTCGGCGGCATTGTGTTTGCCGGACTCGCGGTGGCTTATCGAACTCGCCCGGTCTTTGTCCCGAGTCACGACAACGACCCGGTGGCGCGGTATCGCGCCATGGCGTTATCGCGGCTCCGGTTGATCGGTGTCGGGATCCCGGCGGCGATCGGCCTGCTGGCCGGCATTATCGCGCAGAGCTACTGGGTCCGGATCCAACTGTTCTTGCACGGCGATAACTTTGGTATCAGGGATCCACAGTTCGGCAAGGACCTCGGTTTTTACGCGTTCGAACTGCCATTCTACCGGCTGGTTCTCAGCTACGTGTTTGTTGCGGTATTTCTGGCTTTTGTCGTAAACCTGTTGGCGCACTATATCTTCGGTGGAATCCGGCTGTCCGGACGCACTGGCGCGCTAAGCCGCTTGGCGCGTCTCCAGTTGGTCAGCTTGGTCGGTGTGCTGGTGCTACTTAAAGCTGTTGCCTATTGGCTGGACCGATATGAGTTACTGTCGCGTACGCGTAGCAGTAAGCCGTTCACCGGCGCTGGATACACTGATATCAATGCGGTGCAGCCCGCCAAGCTGATCTTGATAGCGATTGCGCTGATTTGTGCCGCTGCCGTGTTCTCCGCGATCACGTTGCGGGACTTTCGGATTCCTGCCATCGGCCTCGTTTTGCTGATGCTGTCGTCGTTGATCGTGGGTACGGGTTGGCCGTTGATCGTTGAACAGCTCATCGCCAAGCCGGATGCGGTACGCAAGGAAAGCGAGTACATCAGGCGAAGTATCACCGCGACCCGGCATGCCTATGGCCTGACTGAAGATGTGGTGACCTATCGGAATTATATCGGCGACGCGCCTGCGATCGCCCAGCAGATCGCCACTGATCATGCTACCACCTCGAACATCCGGCTACTCGACCCCACGATCGTCAGCCCTGCGTTTACCCAATTCCAGCGGGGTAAGAACTTTTACTACTTCCCCGACCAGCTGTCAATCGACCGTTACCTTGACAAAAAGGGTAACCTCCGTGACTACGTTGTGGCGGCGCGTGAGCTCAACCCGGACCGGTTGATTGACAATCAGCGTGACTGGATCAACCGGCATACCGTTTACACGCACGGGAACGGATTCATAGCGTCGCCGGCAAACACCGTACGCGGTATCGCCAATGACCCGAACCAAAATGGTGGCTATCCTCAATTCTTGGTCAATGTCGTCGGGAACGGTACCGTGGTGTCCGAAGGGCCGGCGCGGCTGGATCAACCCCGCGTTTACTTCGGGCCGGTGATCTCCAATACCTCCGCCGATTATGCGATCGTCGGAAAAAATGGTGATGACCGCGAATACGACTACGAGACCAACACCGATACCAAGAGATACACCTACGCTGGCAGCGGGGGAGTCCCGATCGGCAGCTGGCTGTCCCGTAGTGTGTTCGCTGCGAAATTTGCCGAGCGAAATTTTTTGTTTTCCAGCGTGATTGGTTCCAACAGCAAGATTTTGTTCAACCGCGATCCGGCGCAGCGGGTGGAAGCGGTGGCGCCTTGGTTGACGACTGACAGCAGCGTTTATCCGGCCATCGTGAACAAGCGACTGGTGTGGATCATCGACGGCTACACCACTCTGGACAATTATCCCTACTCTGAACGTACCTCGCTGTCGTCGGCGACTGCCGACTCTACCGAGGTGGCTTTCAATCGATTGGCTCCCGATAAGCGAGTCGCATATATCCGGAACTCGGTGAAGGCCACTGTGGATGCTTACGACGGCGCCGTGACGCTATATCAGCAGGATGAGTATGATCCGGTGCTAAAAGTGTGGATGAAGGTCTTTCCGGGCACCGTCCGACCCAAAGGCGACATTACGCCCGAACTGGCGGAGCATCTCCGCTATCCCGAGGACCTGTTCAAGGTGCAGCGGATGCTGCTGGCTAAGTATCATGTCAATGATCCCGGAACGTTCTTCAACACATCGGATTTCTGGGACGTGCCGCTAGATCCGAATCCGACTGCCAGCAGTTATCAGCCGCCGTACTACATCGTCGCGAAAAACATTCTCAAGAACGACAGGTCGGCATCATACCAGCTGACCAGCGCGATGAATAGGTTCAAGCAAGACTTCCTGGCCGCTTACATCAGCGCCAGCTCTGATCCTGAGACGTACGGCAAGATCACTGTGCTGACCATTCCTGGAAACGTCAACGGTCCCAAACTGGCCAATAACGCGATCACCACCGATCCGGCGGTATCCCAGGATCTGGGTGTGATTGGGCGGGACAACCAAAACCGGATCCGTTGGGGTAACTTGCTGACGCTGCCGGTGGCTCAGGGTGGGCTGCTGTACGTGGAACCTGTCTATGCATCACCGGGTGTCAGCGACGCCGCCTCGTCGTACCCGCGTCTTATTCGCGTGGCAATGATGTACAACGACAAGATTGGATACGGCCCCACCGTCGGTGACGCGCTCACCGGCCTATTCGGGCCCGGCGCGGCTTCCGCTGCTACCGGCATCGAACCGACCGAAGCGGTACCGCCAAAGTCACCCGCAGGTTCTTCGACGCCTCCGATCGCGGTGGTGCCGTCAGCCCCAGACGGGTCGGTTGCATTGTCGGCCGCCAAGGCCGCCGCGCTGCAAGAGATTCAGGCGGTGATTGGCGCGGCTCGCGAAGCACAGAAAAAGGGTGATTTCGTCGCCTATGGTTCGGCGCTACAGCGGCTCGACGACGCCATCACTAAGTTCAACAGCACGAAGTAGG

Protein Sequence 

>ML0644_ML0644_protein
WGCGPLQGCRN_LGVAGL_SWSHWV_SCCCLRVRDWSMRTLSGCGSVSLATVRYSVLCWLPASWCSW_PGWWSAALCLPDSRWLIELARSLSRVTTTTRWRGIAPWRYRGSG_SVSGSRRRSACWPALSRRATGSGSNCSCTAITLVSGIHSSARTSVFTRSNCHSTGWFSATCLLRYFWLLS_TCWRTISSVESGCPDALAR_AAWRVSSWSAWSVCWCYLKLLPIGWTDMSYCRVRVAVSRSPALDTLISMRCSPPS_S__RLR_FVPLPCSPRSRCGTFGFLPSASFC_CCRR_SWVRVGR_SLNSSSPSRMRYARKASTSGEVSPRPGMPMA_LKMW_PIGIISATRLRSPSRSPLIMLPPRTSGYSTPRSSALRLPNSSGVRTFTTSPTSCQSTVTLTKRVTSVTTLWRRVSSTRTG_LTISVTGSTGIPFTRTGTDS_RRRQTPYAVSPMTRTKMVAILNSWSMSSGTVPWCPKGRRGWINPAFTSGR_SPIPPPIMRSSEKMVMTANTTTRPTPIPRDTPTLAAGESRSAAGCPVVCSLRNLPSEIFCFPA_LVPTARFCSTAIRRSGWKRWRLG_RLTAAFIRPS_TSDWCGSSTATPLWTIIPTLNVPRCRRRLPTLPRWLSIDWLPISESHISGTR_RPLWMLTTAP_RYISRMSMIRC_KCG_RSFRAPSDPKATLRPNWRSISAIPRTCSRCSGCCWLSIMSMIPERSSTHRISGTCR_IRIRLPAVISRRTTSSRKTFSRTTGRHHTS_PAR_IGSSKTSWPLTSAPALILRRTARSLC_PFLETSTVPNWPITRSPPIRRYPRIWV_LGGTTKTGSVGVTC_RCRWLRVGCCTWNLSMHHRVSATPPRRTRVLFAWQ_CTTTRLDTAPPSVTRSPAYSGPARLPLLPASNRPKRYRQSHPQVLRRLRSRWCRQPQTGRLHCRPPRPPRCKRFRR_LARLAKHRKRVISSPMVRRYSGSTTPSLSSTARSR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML0644 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

14 show intermediate predicted evidence for PPIs

169 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML0644

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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