fadE24
mL0661c
Probable acyl-CoA dehydrogenase FadE24
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 797293 – 798690
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0661c_fadE24_dna
CATGACTGACACTGCTCCTAGTGCTAAGCCCTCTTCCGTTCGTCTCAAACGAGGCGGTCTTAGGTCCGGCGTCGGAATGCAGCCACACAAGCGGACTGGATTTGACGTCGCAATTGCGATGCTTACTCCGCTTGTCGGCCAGGATTTTCTGGATAAATACCATCTGCGCTATCCGCTCAACCGAGCGTTGCGCTACGGGGTTAAGGCGACGTTCTCCACTGCCGCCGCCACCAGCCGGCAGTTCAAGCGGGTGCAAAACCTGCGCGGTGGCGCAACCCGGCTACAGCCCAGCGGCAGGAACTACTTCGACCTGACGCCAGACGACAACCAAAAGTTGATCGTCGAAACTATCGACGAATTCAGCGCAGAGATACTGCGGCCTGCTGCTCACGACGCTGATGAAGCCGCGGCCTACCCGCCCGACCTTATCGCCAAAGCCGCTAAGTTGGGCATCACCACGATCAACATTCCCGAGTATTTTGACGGCATCGCCGAACGCCGTTCCAGTGTGACCAATGTGTTGGTGGCCGAGGCGCTGGCATATGGCGACATGGGATTGACGCTGCCGATTCTGGCCCCAGGCGGTGTGGCGGCTACACTAACCTATTGGGGCAGCGCCGATCAACAGGCCACCTACCTGAAAGAGTTCACCGGCGAAAATGTCCCCCAGGCCTGTGTGGCCATCGCCGAACCCCAGCCGTTGTTCGACCCCACCCGGCTGAAGACCATCGCCGTGCGCACCCCGTCCGGATACCGGCTCGACGGGGTGAAGTCATTGGTTCCGGCCGCGGCCAGCGCCGAACTGTTCATCATCGGTGCCCAGCTGAATGGCAAGCCAGCATTGTTCATCGTCGAGTCCTCGACTAAAGGCCTGACTGTCAAGGCCGACCCTAGCATGGGGATTCGCGCTGCAGCCTTGGGCCAAGTTGAACTCTGCGGAGTGTCGGCGCCCTTGGACGCCCGGCTGGGTGAAGACGACGCGACGGATAATGACTACTCTGAAGCGATCGCATTGGCCCGGCTAGGATGGGCGGCGCTGGCGGTCGGCACCTCGCATGCAGTGCTGGACTATGTCATGCCGTACGTAAAAGAACGCGAAGCCTTTGGTGAGCCAATCGCGCGTCGCCAGGCTGTCGCGTTCATGTGCGCCAACATCGCTATCGAGTTAGACGGGCTGCGGCTGATCACGTGGCGTGGCGCGTCCCGCGCCGAACAAGGCCTCTCATTCGCCCGGGAAGCAGCACTGGCCAAGCGACTCGGCTCCGACAAAGCCATGCAAATCGGCCTGGACGGCGTGCAACTGCTGGGCGGTCACGGCTTCATCAAAGAGCACCCGGTCGAACGCTGGTATCGCGATCTGCGGGCGATCGGTGTCGCCGAGGGCGTCGTAGTTATCTA

Protein Sequence 

>ML0661c_FadE24_protein
HD_HCS_C_ALFRSSQTRRS_VRRRNAATQADWI_RRNCDAYSACRPGFSG_IPSALSAQPSVALRG_GDVLHCRRHQPAVQAGAKPARWRNPATAQRQELLRPDARRQPKVDRRNYRRIQRRDTAACCSRR__SRGLPARPYRQSR_VGHHHDQHSRVF_RHRRTPFQCDQCVGGRGAGIWRHGIDAADSGPRRCGGYTNLLGQRRSTGHLPERVHRRKCPPGLCGHRRTPAVVRPHPAEDHRRAHPVRIPARRGEVIGSGRGQRRTVHHRCPAEWQASIVHRRVLD_RPDCQGRP_HGDSRCSLGPS_TLRSVGALGRPAG_RRRDG__LL_SDRIGPARMGGAGGRHLACSAGLCHAVRKRTRSLW_ANRASPGCRVHVRQHRYRVRRAAADHVAWRVPRRTRPLIRPGSSTGQATRLRQSHANRPGRRATAGRSRLHQRAPGRTLVSRSAGDRCRRGRRSYL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FadE24 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

29 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FadE24

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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