fprA
mL0666c
Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 801977 – 803347
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0666c_fprA_dna
ATTGCGTCCACACCACATACATCACATAGCCATAGTTGGCTCGGGGCCATCGGGATTTTTCGCCGCGGCATCCGTGTTGAAGGCCGCTGACGCCTCCGACGAGATCAACGTTGCCGTCGACATGCTGGAGATGCTGCCCACCCCGTGGGGACTGGTCCGCTCTGGTGTCGCACCCGATCACCCCAAGATCAAATCGATCAGCAAGCAGTTCGAGAAGACCGCTGAGGACCCGCGGTTCCGCTTCTTCGGCAATGTGATTGTCGGTAAACACATCGAGCCTGCCGAACTCGCCGAACGCTACGATGCCGTGATATATGCTGTCGGGGCGCAGTCCGACCGCGCTTTGAACATCCCCGGTGAAGACCTGCCAGGCAGTATCGCCGCTGTCGATTTCGTGGGTTGGTATAACGCACACCCCAACTTCCACGAGAGGTCACCCGACCTTTCGGGCAGTCGCGCAGTGGTTATTGGCAACGGCAACGTCGCACTCGACGTCACACGCATCCTAATCACCGATCCCGACGTACTGGCATTCACCGATATCGCCGACCACGCACTAGAGTCACTGCGCCCGCGCGGGATCGAGGAAGTGGTGATCGTTGGCCGCCGCGGGCCATTACAGACAGCGTTCACCACACTGGAGCTGCGTGAGCTAGCAGACATCGAAGGGGTCGACGTGCTTGTCGATCCTGCCCAGCTGGAGGGCATCAGTGACGAGAACGCGGCCGCGGCGGGCAAGACGACCAGGCAGAACATCAAAGTGTTACGCGACTACACTGTGCGCACGCCCAAACCCGGCCATCGTCGGATTGTGTTCCGATTCCTGACTTCCCCAATTGAAATCAAAGGCAAAGGCAAGGTGGAGAGGATCGTTCTCGGTCAAAACGAACTTGTCACCGACGACAACGGGCGGGTGGCAGCCAAAGACACCGGTGTTCGCGAGGAGCTGCCGGCTCAGTTGATTGTGCGGTCGATCGGTTATCGCGGCGTCCCTACGCCGGGGTTACCATTCGACGACAGTAGCGTAACCATCCCCAACACCAACGGCCGGGTGAACGGCAGCCGAAACGAGTACGTCGTCGGGTGGATCAAACGCGGGCCGACCGGGGTGATCGGCACCAACAAGAAGGACTCCCAAGACACTGTCGACACCTTGATGGAGAATCTGGCTGGCGCCAATGATACCGAAAAGTTCGGCGCAGACCACGCCGACCGGCTGGCCGAGTGGCTGGCCGAACGGCAACCGAAGCTGGTCACGTCGGCGCACTGGCAGGCCATCGACCGCTTTGAGCGAGCGGCCGGCGAACCGCACGGCCGCCCCCGCGTTAAGCTGCCGAACCTCGCCGAGCTGCTGCGGATCGGGCACGGCTG

Protein Sequence 

>ML0666c_FprA_protein
IASTPHTSHSHSWLGAIGIFRRGIRVEGR_RLRRDQRCRRHAGDAAHPVGTGPLWCRTRSPQDQIDQQAVREDR_GPAVPLLRQCDCR_THRACRTRRTLRCRDICCRGAVRPRFEHPR_RPARQYRRCRFRGLV_RTPQLPREVTRPFGQSRSGYWQRQRRTRRHTHPNHRSRRTGIHRYRRPRTRVTAPARDRGSGDRWPPRAITDSVHHTGAA_ASRHRRGRRACRSCPAGGHQ_RERGRGGQDDQAEHQSVTRLHCAHAQTRPSSDCVPIPDFPN_NQRQRQGGEDRSRSKRTCHRRQRAGGSQRHRCSRGAAGSVDCAVDRLSRRPYAGVTIRRQ_RNHPQHQRPGERQPKRVRRRVDQTRADRGDRHQQEGLPRHCRHLDGESGWRQ_YRKVRRRPRRPAGRVAGRTATEAGHVGALAGHRPL_ASGRRTARPPPR_AAEPRRAAADRARL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FprA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

31 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FprA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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