prfB
mL0667
Probable peptide chain release factor 2 PrfB (RF-2)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 803527 – 804651
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0667_prfB_dna
TGGAACCTGACCGACAAACCGACATCGCTGCTCTTGACTCCACCTTGACCACGGTGGAGCGGGTGCTCGACGTGGAGGGTCTGCGCACCCGCATCGAGAAACTTGAGCATGAGGCGTCCGATCCGAAACTGTGGGATGACCAAGTCCGCGCGCAACGTGTGACCAGCGAGTTATCTCACGCTCAGGGCGAGCTGCGCCGAATCGAGGAGCTGCGGCGACGTTTAGATGACTTGCCGGTACTCTACGAATTAGCGGCTGAGGAAAGGGCTGCGGCCGCCGCTAGCGGAATGGAGGCCTTCGCTGAGGCTGATGCCGAACTCAAGGCGCTGCGCGTCGATATCGAAGCCACCGAGGTGCGCACGCTGTTGTCAGGCGAATATGACGAGCGCGAAGCGCTGATCACCATACGTTCCGGTGCTGGCGGAGTGGATGCCGCGGACTGGGCCGAAATGCTGATGCGGATGTATATTCGATGGGCAGAGCAGCACAAATACGGCGTCGAGGTGTTAGACACCTCCTATGCCGAAGAAGCCGGTGTCAAAAGTGCCACGTTCGCCGTGCACGCGCCGTTCGCCTATGGCACGTTGGCGAGCGAGCAGGGCACCCACCGGCTGGTCCGGATCAGCCCGTTCGACAACCAGAGTCGGCGGCAGACCTCGTTCGCTGAGGTCGAAGTGTTGCCTGTGGTGGAGATCACCGATCACATCGACATTCCCGAAGGCGATGTGCGCGTCGATGTCTACCGATCCAGCGGTCCTGGCGGCCAGTCGGTCAACACCACCGACTCTGCGGTACGGCTAACTCACGTCCCAACCGGTCTTGTCGTTACCTGCCAGAACGAGAAATCGCAGCTGCAGAACAAGGTATCGGCGATGCGCGTGCTGCAAGCAAAGTTGTTGGAGCGTAAGCGTTTAGAAGAACGCGCTGAGCTAGATGCATTAAAGGGTAGGGGTGGCAGCTCGTGGGGCAATCAGATACGGTCCTATGTACTGCACCCTTATCAGATGGTCAAGGATCTGCGAAACGAGTACGAGGTGGGTAACCCGACAGCTGTACTTGACGGAGACATCGACGGGTTCCTGGAAGCCGGGATTCGTTGGCGCAACAGACGTGATATCAGCTAAC

Protein Sequence 

>ML0667_PrfB_protein
WNLTDKPTSLLLTPP_PRWSGCSTWRVCAPASRNLSMRRPIRNCGMTKSARNV_PASYLTLRASCAESRSCGDV_MTCRYSTN_RLRKGLRPPLAEWRPSLRLMPNSRRCASISKPPRCARCCQANMTSAKR_SPYVPVLAEWMPRTGPKC_CGCIFDGQSSTNTASRC_TPPMPKKPVSKVPRSPCTRRSPMARWRASRAPTGWSGSARSTTRVGGRPRSLRSKCCLWWRSPITSTFPKAMCASMSTDPAVLAASRSTPPTLRYG_LTSQPVLSLPARTRNRSCRTRYRRCACCKQSCWSVSV_KNALS_MH_RVGVAARGAIRYGPMYCTLIRWSRICETSTRWVTRQLYLTETSTGSWKPGFVGATDVISAN

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PrfB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

59 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PrfB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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