trpS
mL0686
Probable tryptophanyl-tRNA synthetase TrpS (TRYPTOPHAN--TRNA LIGASE) (TRPRS) (TRYPTOPHAN TRANSLASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 822127 – 823158
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0686_trpS_dna
TGAGTACCGCTACCGGATTCAGCAGGATTTTCTCCGGCGTGCAGCCCACTTCTGATTCGCTTCACCTCGGTAACGCGTTGGGTGCCATCACCCAGTGGGTTGCGCTGCAGTACGATCATCCGGACGAATACGAAGCGTTCTTTTGTGTGGTTGACCTGCACGCCATAACCATCGCGCAAGATCCCGAGACACTGTGGCGTCGGACCCTGGTCACTGCCGCGCAATACCTGGCCTTGGGCATCGATCCGGGGCGCGCCGTCGTTTTCGTGCAAAGCCATGTACCAGCCCACACGCAGTTGGCGTGGGTGCTGGGCTGCTTTACCGGCTTCGGACAGGCGTCTCGGATGACACAGTTCAAGGACAAGGCGCTGCGTCAGGGTGCCGACTCCACCACCGTCGGCCTGTTCACCTATCCTGTGTTGCAGGCTGCCGACGTGTTGGCCTACGATACTGATCTGGTGCCCGTGGGGGAGGATCAGCGGCAGCACTTGGAGCTTGCGCGTGACTTGGCGCAGCGGTTCAATAGCCGCTTCCCGGACACCTTTGTGGTTCCCGACATGTTCATTCCCAAGATGGCTGCCAAGATCTACGATTTGGCCGACCCAACGTCGAAAATGAGTAAATCGGCGTCCAGTGATGCTGGGTTGATCAACCTGCTCGACGATCCGGCGTTGTCCGTCAAGAAAATTCGAGCAGCGGTGACCGACAGTGAACGGGAGATCCGGTATGATCCGGAGGTCAAGCCGGGTGTGTCGAACTTGTTGAACATCCAGTCCGCGGTCACCGGGGTTGATGTCGATACCCTTGTGCAGCGCTACGTTGGGCACGGTTATGGCGACCTGAAGAAAGACACCGCCGAGGCCGTGGTCGAGTTCGTCAGCCCGATCAAGGACCGGGTCGACGAATTGATGGCCGATCTAACCGAATTGGAGGTTGTTCTTGCGGTCGGAGCGCAGCGTGCTCAAGATGTGGCTGGCAAGACGATGCAGCGGGTTTACGACCGGCTGGGCTTTCTTCCGCAACGGGGGTAAG

Protein Sequence 

>ML0686_TrpS_protein
VPLPDSAGFSPACSPLLIRFTSVTRWVPSPSGLRCSTIIRTNTKRSFVWLTCTP_PSRKIPRHCGVGPWSLPRNTWPWASIRGAPSFSCKAMYQPTRSWRGCWAALPASDRRLG_HSSRTRRCVRVPTPPPSACSPILCCRLPTCWPTILIWCPWGRISGSTWSLRVTWRSGSIAASRTPLWFPTCSFPRWLPRSTIWPTQRRK_VNRRPVMLG_STCSTIRRCPSRKFEQR_PTVNGRSGMIRRSSRVCRTC_TSSPRSPGLMSIPLCSATLGTVMAT_RKTPPRPWSSSSARSRTGSTN_WPI_PNWRLFLRSERSVLKMWLARRCSGFTTGWAFFRNGGK

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding TrpS with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

18 show weak predicted evidence for PPIs

View all pooled AlphaFold results for TrpS

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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