dacB1
mL0691c
Probable D-alanyl-D-alanine carboxypeptidase DacB1 (PENICILLIN-BINDING PROTEIN) (DD-PEPTIDASE) (DD-CARBOXYPEPTIDASE) (PBP) (DD-TRANSPEPTIDASE) (SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE) (D-AMINO ACID HYDROLASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 827878 – 829113
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0691c_dacB1_dna
GATGTCTTTTTTACGTTCCACCGCATGCCTGGCAGCAGCAGTTTTCGCGATCGTTGGACCAGTCGCGCTGGACCTGCCTACCGCCGTGCCAGTCGGACATGCCGAACCGAATGCCGGACCCAACGCCGGTCCAGCAACATGCCCATACCAGGTGTCCACTCCACCAGCGGTGGACTCGTCGGAAGTCCCCCAAACCGGTAACCCACCGATGCCGCTGGCAGTGCCGCCCAAACCGGTCGGCGGCGCGGCACTGAACAGCTGCGGAATCGTCACCGCTCCAGACACGCCGCCAGTACCAGGTGACCTCTCCGCCGAGGCGTGGCTGGTGGCGGATCTGAACAGCGGCGCCGTCATCGCTGCCCGCGATCCACACGGCCGACACCGCCCGGCCAGCATCATTAAAGTGCTGTTAGCCATGGCGTCCATCAACACGCTCAACCTTAACAAATCGGTCGCCGGAACTGCCGAGGACGCCGCCGCCGAGGGCACCAAGGTCGGCGTCCACGACGGCGGCACATACACTATCAACCAACTACTGCACGGGTTGTTGATGCAGTCGGGCAATGACGCCGCGCACTCGTTGGCCATGCAGCTCGGCGGTATGCAGCAAGCGCTGCAGAAGATCAACGTGCTGGCCGCCAAACTCGGCGGCCAGGATACTCGGGTAGCAACGCCATCGGGGCTGGACGGGCCGGGCATGAGCACGTCGGCCTACGACATCGGCTTGTTCTACCGGTACGCCTGGCAGAACCCCTCGTTCAGCAACATCGTCGCTACCCGGACCTTCAATTTCCCCGGTCCCGGCGACCATCCCGGCTACCAGCTGGAAAACGACAACCAGTTGCTCTACCAATATCCGGGTGCGTTGGGCGGCAAGACCGGCTACACCGACGACGCTGGCCAAACGTTTGTGGGCGCCGCCAACCGTAATGGTCGACGGCTGATGGCGGTGCTGCTACACGGGACCCGGCAGCCGATTGCGCCGTGGGAACAAGCAGCGCACTTGTTGGACTATGGCTTTAGCACCGCAGTCGGAACCCAGATAGGCACACTGATCGAACCCGACCCCACGGTGGCCGGTAACGCAGATCGGCACGGCCATGGCCTACAAGCCGCCGGAATCATGTCATCAAACGACACGCTTCCGGTACGAATAGGCGTAGCGGTCGTCGGTACGTTGATCGTGTTCGGCTTAATCATGATCACGCGTTCGCTAAACCGCCGGCCACAACACTG

Protein Sequence 

>ML0691c_DacB1_protein
DVFFTFHRMPGSSSFRDRWTSRAGPAYRRASRTCRTECRTQRRSSNMPIPGVHSTSGGLVGSPPNR_PTDAAGSAAQTGRRRGTEQLRNRHRSRHAASTR_PLRRGVAGGGSEQRRRHRCPRSTRPTPPGQHH_SAVSHGVHQHAQP_QIGRRNCRGRRRRGHQGRRPRRRHIHYQPTTARVVDAVGQ_RRALVGHAARRYAASAAEDQRAGRQTRRPGYSGSNAIGAGRAGHEHVGLRHRLVLPVRLAEPLVQQHRRYPDLQFPRSRRPSRLPAGKRQPVALPISGCVGRQDRLHRRRWPNVCGRRQP_WSTADGGAATRDPAADCAVGTSSALVGLWL_HRSRNPDRHTDRTRPHGGR_RRSARPWPTSRRNHVIKRHASGTNRRSGRRYVDRVRLNHDHAFAKPPATTL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding DacB1 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

4 proteins show strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

74 show weak predicted evidence for PPIs

View all pooled AlphaFold results for DacB1

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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