sdhB
mL0696c
Probable succinate dehydrogenase (iron-sulfur protein subunit) SdhB (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 833873 – 834667
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0696c_sdhB_dna
GATGGCCGTTGAACCTGTCGAGGTCAAGTCGCTCGAACCTCCCCGACCGCCGATTTCGGATGACGCGGTGATGGTGACCGTGAAGATCGCACGATTCAACCCAGACAACCCCGATGCATTTGCGGAAACCGGTGGCTGGCAGAGCTTCCGGGTGCCCTGCCTGCCCACCGACCGGCTGCTAAACCTGCTGATCTACATCAAGGGTTACCTGGACGGCACACTCACCTTCCGGAGATCCTGCGCGCACGGGGTGTGCGGCTCTGATGCTATGCGGGTTAACGGCGTCAACCGGCTGGCCTGCAAGGTACTGATGCGCGACCTACTACCAAAAAAAGCGGGCAAGAACCTGACCATCACAGTCGAACCGATCCGCGGGCTGCCGGTGGAAAAGGACCTGGTGGTCGACATGGAACCATTCTTCGACGCCTACCGCGCGGTGAAACCCTACCTGATTACCAGCGGCAACCCGCCGACCCGAGAGCGCATCCAAAGCCCGACCGACCGCGCTCGCTACGACGACACCACCAAATGTATCCTGTGCGCATGCTGCACCACCAGCTGCCCGGTGTTCTGGAGCGAGGGCACCTACTACGGTCCCGCTGCGATCGTCAACGCGCATCGCTTCATTTTCGACAGCCGCGATGAGGGTGCCGGCGAACGCCTGACCCTCCTCAACGAGGTCGACGGAGTATGGCGGTGCCGAACCACGTTCAACTGCACCGAATCCTGCCCACGCAACATAGAGGTGACCAAAGCGATCCAAGAAGTCAAGCGCGCGCTAATGTTCTCGCGCTA

Protein Sequence 

>ML0696c_SdhB_protein
DGR_TCRGQVARTSPTADFG_RGDGDREDRTIQPRQPRCICGNRWLAELPGALPAHRPAAKPADLHQGLPGRHTHLPEILRARGVRL_CYAG_RRQPAGLQGTDARPTTKKSGQEPDHHSRTDPRAAGGKGPGGRHGTILRRLPRGETLPDYQRQPADPRAHPKPDRPRSLRRHHQMYPVRMLHHQLPGVLERGHLLRSRCDRQRASLHFRQPR_GCRRTPDPPQRGRRSMAVPNHVQLHRILPTQHRGDQSDPRSQARANVLAL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding SdhB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

3 proteins show strong predicted evidence for PPIs

12 show intermediate predicted evidence for PPIs

83 show weak predicted evidence for PPIs

View all pooled AlphaFold results for SdhB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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